| Project/Area Number |
11480192
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biophysics
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| Research Institution | Yokohama City University (2001)
Kyoto University (1999-2000) |
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Principal Investigator |
KIDERA Akinori okohama City University, Graduate School of Intergrated Science, Professor, 大学院・総合理学研究科, 教授 (00186280)
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| Co-Investigator(Kenkyū-buntansha) |
KINOSHITA Kengo Yokohama City University, Graduate School of Integrated Science, Instructor, 大学院・総合理学研究科, 助手 (60332293)
KITAO Akio Kyoto University, Graduate School of Science, Research Assistant, 大学院・理学研究科, 助手 (30252422)
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| Project Period (FY) |
1999 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥13,500,000 (Direct Cost: ¥13,500,000)
Fiscal Year 2001: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 2000: ¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 1999: ¥8,400,000 (Direct Cost: ¥8,400,000)
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| Keywords | proteins / anharmonic vibration / vibrational reluxation / mode coupling / Fermi resonance / myoglobin / 非線型振動 / フレルミ共鳴 / ミオグロビンL |
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| Research Abstract |
Anharmonic dynamics of a protein molecule was studied by molecular dynamics simulations of the vibrational energy transferred of myoglobin. It was found that there are two distinct schemes of the energy transfer, depending on temperature. At near zero temperature, the vibrational energy is transferred as a process of the Fermi resonance, from one mode exclusively to a limited number of modes having resonance frequencies. On the other hand, as temperature increases, the resonance type transfer is dominated by the off-resonance energy transfer through the various mode-coupling terms. Near room temperature, the energy transfers involves the higher order coupling terms together with the indirect transfers through intermediate modes. At about 170 K, we have observed a glass transition-line phenomenon in the vibrational energy transfer.
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