| Budget Amount *help |
¥13,200,000 (Direct Cost: ¥13,200,000)
Fiscal Year 2002: ¥2,600,000 (Direct Cost: ¥2,600,000)
Fiscal Year 2001: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 2000: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 1999: ¥5,100,000 (Direct Cost: ¥5,100,000)
|
|---|
| Research Abstract |
The pathogenesis of periodontitis is generally accepted to be initiated by specific bacteria, however, the occurrence rate of specific periodontal bacteria in children and adolescents remains unknown. In the present study, 10 putative periodontopathic bacteria were longitudinally examined in plaque and saliva samples from 119 periodontally healthy children (2 - 15 years old) using a polymerase chain reaction method. Capnocytophaga ochracea, Capnocytophaga sputigena, and Acrinobacillus actinomycetemcomitans were frequently found in saliva, and tended to be detected in saliva for the rest of the study, whereas Porphyromonas gingivalis, Treponema denticola, and Prevotella intermedia were rarely detected. Prevotella nigrescens was more frequently detected in plaque and its prevalence increased with age. Campylobacter rectus and Eikenella corrodens were sometimes detected from both plaque and saliva, while Bacteroides forsythus was less occasionally detected in saliva. Our findings suggest that A. actinomycetemcomitans, C. ochracea, C. sputigena, P. nigrescens, C. rectus, and E. corrodens are common members of the oral microbial flora of healthy children, whereas P. gingivalis, P. intermedia, and T. denticola appear to be transient organisms.
|
