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Development of a System Recording Neural Activity from Moving Animals

Research Project

Project/Area Number 11558095
Research Category

Grant-in-Aid for Scientific Research (B).

Allocation TypeSingle-year Grants
Section展開研究
Research Field 神経・脳内生理学
Research InstitutionTokyo Metropolitan Institute for Neuroscience

Principal Investigator

SASAKI Shigeto  Tokyo Metropolitan Institute for Neuroscience, Staff Scientist, 東京都神経科学総合研究所, 参事研究員 (50110490)

Co-Investigator(Kenkyū-buntansha) MOGI Nobuaki  MicroOpt Co. Ltd, President, 代表取締役
OKA Mieko  Tokyo Metropolitan Institute for Neuroscience, Staff Scientist, 東京都神経科学総合研究所, 研究員 (80270669)
Project Period (FY) 1999 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥10,900,000 (Direct Cost: ¥10,900,000)
Fiscal Year 2000: ¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 1999: ¥7,500,000 (Direct Cost: ¥7,500,000)
KeywordsPetarode / Multiple Unit / Spike sorting / Unit Recording / Moving animal / Spinal cord / Electrode array / スパイクソーター
Research Abstract

A major aim of this study is to develop a system that allow simultaneous recording of unit activities from multiple sites in the brain or spinal cord of moving animals.
1. Development of pentarode We developed a tungusten electrode (500 mum in diameter) in which five thin cupper or silver wires of 20-50 mum thick are aranged along its long axis upto the tip of the electrode. Simultaneous Recoding from 5 diffent foci of the electrode can be made by removing the insulation of thin wires locally (pentarode).
2. Development of a method recording from spinal cord We developed a method recording unit activities from the spinal cord in moving animals. We placed teflon-coated thin silber wires, embeded in a glass microelectrode of 2-3 mm length into the spinal cord and glued to the spinal cord.
3. Development of a small maniplator We developed a small micro-maniplater (20 x 6 x 11 mm) which allows movements up to 15 mm in one direction. An array of 12 electorodes could be monted on it and could be implanted on the head of animals chronically.
4. Development of a system analysing correlation between neural activitiesand behavior We developed a system correlating unit activities with various parameters of movements using PC-Unix (Linux), after sorting spikes by a template matching technique.

Report

(3 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • Research Products

    (29 results)

All Other

All Publications (29 results)

  • [Publications] Sasaki S: "Direct connection of nucleus reticularis gigantocellularis neurons with neck motoneurons."Exp Brain Res. 128. 527-530 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S,Iwamoto Y: "Axonal trajectories of the nucleus reticularis gigantocellularis neurons in C3-C4 segments"Neurosci Lett. 264. 137-140 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S,Isa T and Naito K: "Effects of lesion of pontomedullary reticular formation on visually triggerd vertical and oblique orienting movements in alert cats."Neurosci Lett. 265. 13-16 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Yoshimura K,Sasaki S and Takeuchi H: "Postural adjustment in cats during orienting"J J Physiol. 49 Suppl. S164 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S,Yoshimura K,Naito K And Takeuchi H: "Velocity and position guided orienting in unrestrained cats"Neurosci Res. Suppl24. S33 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Isa T and Sasaki S: "Neural mechanisms for the control of visually guided orienting movements of the Head. In Motor Control Today and Tomorrow"Academic Publishing House G.N.Gantchov, S.Mori, J Massion. (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S,Yoshimura K and Naito K: "Control of orienting and posture in cats. In : "From Basic Motor Control to Functional Recovery""Academic Publishing House G.N.Gantchov,S.Mori,J Massion. (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Isa T., Sasaki S.: "Brainstem control of head movements during orienting ; organization of the premotor circuits"Prog Neurobiol. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S.: "Direct connection of the nucleus reticularis gigantocellularis neurons with neck motoneurons in cats."Exp. Brain Res.. 128. 527-530 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S., Isa T.and Naito K.: "Effects of lesion of pontomedullary reticular formation on visually triggered vertical and oblique head orienting movements in alert cats."Neurosci. Lett.. 265. 13-16 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S.and Iwamoto Y.: "Axonal trajectories of the nucleus reticularis gigantocellularis neurons in the C3-C4 segments in cats."Neurosci. Lett.. 264. 137-140 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Isa T.and Sasaki S.: "Neural mechanisms for the control of visually guided orienting movements of the head."Motor Control Today and Tomorrow, Eds, G.N.Gantchev, S.Mori and J.Massion, Bulgaria Academic Publishing House, Sofia. 57-69 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Hoshino Y., Kurokawa T., Hongo H.and Sasaki S.: "Abnormal large potentials arising from dorsal column fibers in the region of chronically compressed spinal cord."EGG J.. 110. 305-316 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S., Yoshimura K.and Naitio K.: "Subtypes of orienting"Neurosci. Res. Suppl 23. S6 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S., Yoshimura K.and Naito K.: "Pathways controlling head orienting and thei functions in the cat and monkey."Neurosci. Res.. Suppl 22. S57 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S.Yoshimura K.and Natio K.: "Control of orienting and posture in cats."Bulgaria Academic Publishing House, Sofia. 40-46 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sasaki S: "Direct connection of nucleus reticularis gigantocellularis neurons with neck motoneurons."Exp Brain Res. 128. 527-530 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Sasaki S,Iwamoto Y: "Axonal trajectories of the nucleus reticularis gigantocellularis neurons in C3-C4 segments"Neurosci Lett. 264. 137-140 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Sasaki S,Isa T and Naito K: "Effects of lesion of pontomedullary reticular formation on visually triggerd vertical and oblique orienting movements in alert cats."Neurosci Lett. 265. 13-16 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Yoshimura K,Sasaki S and Takeuchi H: "Postural adjustment in cats during orienting"J J Physiol. 49 Suppl. S164 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Sasaki S,Yoshimura K,Naito K And Takeuchi H: "Velocity and position guided orienting in unrestrained cats"Neurosci Res. Suppl 24. S33 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Isa T and Sasaki S: "Neural mechanisms for the control of visually guided orienting movements of the Head.In Motor Control Today and Tomorrow"Academic Publishing House G.N. Gantchov, S.Mori, J Massion. (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Sasaki S,Yoshimura K and Naito K: "Control of orienting and posture in cats. In : "From Basic Motor Control to Functional Recovery""Academic Publishing House G.N. Gantchov, S.Mori, J Massion. (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Sassaki S: "Direct connection of nucleus reticularis gigantocellularis neurons with neck motoneurons"Exp Brain Res.. 128. 527-530 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Sassaki S, Iwamoto Y: "Axonal trajectories of the nucleus reticularis gigantocellularis neurons in C3-C4 segments in cats"Neurosci. Lett.. 264. 137-140 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Sasaki S, Isa T, Naito K: "Effects of lesion of pontomedullary reticular formation on visually triggered vertical and oblique head orienting movements in alert cats"Neurosci. Lett.. 265. 13-16 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Hoshino Y., Kurokawa T., Hongo T., Sasaki S.: "Abnormal large potentials arising from dorsal column fibers in the region of chronically compressed spinal cord"EEG J.. 110. 305-316 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Isa T., Sasaki S.: "Neural mechanisms for the control of visually guided orienting movements of the head. In : "Motor Control Today and Tomorrow""Academic Publishing House, G. N. Gantchev, S. Mori, J. Massion. (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Sasaki S., Yoshimura K., Naito K.: "Control of orienting and posture in cats. In : "From Basic Motor Control to Functional Recovery""Academic Publishing House, N. Gantchev & G. N. Gantchev. (1999)

    • Related Report
      1999 Annual Research Report

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Published: 1999-04-01   Modified: 2016-04-21  

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