| Project/Area Number |
11558105
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
INOU Norio Tokyo Institute of Technology, Graduate School of Science and Engineering, Professor, 大学院・理工学研究科, 教授 (70126308)
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| Co-Investigator(Kenkyū-buntansha) |
MURAYAMA Hisashi Kureha Chemical Industry Co., LTD., Biomedical Research Laboratories, Sector Manager, 生物医学研究所, 研究主任
MAKI Koutarou University of Showa, Department of Orthodontics, Lecturer, 歯学部, 講師 (80219295)
UJIHASHI Sadayuki Tokyo Institute of Technology, Graduate School of Information Science and Engineering, Professor, 大学院・情報理工学研究科, 教授 (80016675)
KOSEKI Michihiko Tokyo Institute of Technology, Graduate School of Science and Engineering, Research Associate, 大学院・理工学研究科, 助手 (50334503)
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| Project Period (FY) |
1999 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥12,800,000 (Direct Cost: ¥12,800,000)
Fiscal Year 2001: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 2000: ¥5,800,000 (Direct Cost: ¥5,800,000)
Fiscal Year 1999: ¥4,900,000 (Direct Cost: ¥4,900,000)
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| Keywords | Robustness of bone / Vertebra / Individual modeling / CT data / Stress analysis / 固体別モデリング |
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| Research Abstract |
The purpose of this research is to develop a new system to evaluate mechanical robustness of a vertebral body with intact states. To realize the system, this research project investigated biomechanical properties of vertebral body with a computational method. First, sectional images of a rat's vertebral body were taken using pQCT. Then, a three-dimensional finite element model of the vertebra was generated by an automated modeling method developed by authors. Strength of bone and Young's modulus for the each element were calculated by the X-ray CT number. Second, a compression test using the vertebral body was performed with the same vertebral bone. Stress analysis was executed under the compressive loading conditions. Finally, a stress ratio η=σ/σ_B was calculated to evaluate the mechanical robustness of the bone. The portion of the fracture was well in accord with that of large η in the computational result.
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