| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,600,000)
Fiscal Year 2001: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2000: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1999: ¥800,000 (Direct Cost: ¥800,000)
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| Research Abstract |
We examined how facial expressions of emotion can affect observer's mood, liking, and recognition of the face in Japanese and American students. The results were ; 1)the old faces were judged more attractive (mere exposure effect), 2)exposure to an emotional expression, sad in particular, affected the observer's mood, 3)this effect is more prominent when only 80 percent, not 100 percent, of faces showed the same emotion, and 4)happy faces were liked more than sad faces, yet 5)happy and sad faces were recognized equally well. The findings 4) and 5) together indicate separate mechanisms underlying implicit (attractiveness) and explicit (recognition) memory. No significant cultural difference was obtained.
1. Decidualizing process of endometrial stromal fibroblasts involved in intracellular c-AMP signalling system and this process was inhibited by estrogen receptor inhibitors and aminopeptidase inhibitors.
2. Serum-free culture medium from trophoblasts inhibited prostaglandins production in decidual cells.
3. Production of endotherial growth factors and expression of thymidine phosphorylase in decidual cells were increased by co-culture of monocyte or TNF α and IL6 and IL8 also stimulated as well. Otherwise, co-culture of monocyte or addition of TNF α induced apoptosis in decidual cells.
4. Serum from preeclanptic patients inhibited cell growth of trophoblasts, compared with normal pregnant women. Monocytes from preeclampsia inhibited trophoblast cell growth significantly in co-couture system as well. These inhibition of cell growth was due to apoptosis.
It is suggested that cell-cell interaction at the feto-maternalinterface might play an important role in placental development and maintenance of pregnancy.
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