• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Evolutionary mechanism of vertbrate mitochondrial DNA

Research Project

Project/Area Number 11640624
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 遺伝
Research InstitutionThe Institute of Statistical Mathematics

Principal Investigator

HASEGAWA Masami  Inst. Statist. Math., Professor, 予測制御研究系, 教授 (60011657)

Co-Investigator(Kenkyū-buntansha) HASHIMOTO Tetsuo  Inst. Statist. Math., Associate professor, 調査実験解析研究系, 助教授 (50208451)
Project Period (FY) 1999 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2000: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 1999: ¥1,900,000 (Direct Cost: ¥1,900,000)
Keywordsvertebrate / mitochondria / evolution / mechanism / phylogeny / entheria / maximum likelihood / カメ類 / ミトコンドリアゲノム / ミトコンドリア / カメ / 最尤法 / 翼手類目 / 食虫目
Research Abstract

It is prerequisite to establish the phylogenetic relationships among organisms in the study of evolution and biodiversity. Therefore, molecular phylogenetics is of fundamental importance in evolutionary biology. In this project, we developed methods for inferring molecular phylogeny with the maximum likelihood, which has a sound statistical basis, and applied the methods in analyzing mitochondrial genome data.
Extensive phylogenetic analyses of updated sequence data of mammalian mitochondrial genomes were carried out using the maximum likelihood method in order to resolve deep branchings in eutherian evolution. The divergence times in the mammalian tree were estimated by a relaxed molecular clock of the mitochondrial proteins calibrated with multiple references. A Chiroptera/Eulipotyphla (i.e., bat/mole) clade and a close relationship of this clade to Fereuungulata (Carnivora + Perissodactyla + Cetartiodactyla) were reconfirmed with high statistical significance. However, support for the monophyly of Fereuungulata relative to the Chiroptera/Eulipotyphla clade was fragile, and we suggest that the 3 branchings among Carnivora, Perissodactyla, Cetartiodactyla and Chiroptera/Eulipotyphla occurred successively in a short time period, estimated to be approximately 77 MyrBP.The Chiroptera/Eulipotyphla divergence was estimated to roughly coincide with the Cretaceous-Tertiary boundary (65 MyrBP). The monophyly of Rodentia, the Lagomorpha/Rodentia clade (traditionally called Glires), and the Afrotheria/Xenarthra clade were preferred over alternative relationships, but the supports of these clades were not strong enough to exclude other possibilities.

Report

(3 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • Research Products

    (10 results)

All Other

All Publications (10 results)

  • [Publications] Cao.Y. et.al.: "Phylogenetic position of turtles among amntotes : evidence from mitochondrial and nuclear genes"Gene. 259. 139-148 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Cao Y.et al.: "Interordinal relationship and timescales of entherian evolution as inferred from mitochondrial genome date"Gene. 259. 149-158 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Onuma,M. et al.: "A close relationship of Chiroptera with Eulipotyphla suggested by four mitochondrial genes"Zoological Science. 17. 1327-1332 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Cao, Y.et al.: "Phylogenetic position of turtles among amntotesi evidence from mitochondrial and nuclear genes"Gene. vol. 259. 139-148 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Cao, Y.et al.: "Interordinal relationship and time scales of entherian evolution as inferred from mitochondria genome date"Gene. vol. 259. 149-158 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Onuma, M.et al.: "A close relationship of chiroptera with Enlipotyphla suggested by four mitochondrial genes"Eoological Science. vol. 17. 1327-1332 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Cao,Y. et al.: "Phylogenetic position of turtles among amnrotes : evidence from mitochondrial and nuclear genes"Gene. 259. 139-148 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Cao.Y. et al.: "Interordinal relathionship and timescales of entherian evolution as inferred from mitochondrial genome date"Gene. 259. 149-158 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Onuma,M. et al.: "A close relationship of Chiroptera with Eulipotyphla suggested by four mitochondrial genes"Zoological Science. 17. 1327-1332 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Cao, Y., Hasegawa, M.: "Model dependence of the phylogenetic inference"Genes and Genetic Systems. 74. 211-217 (1999)

    • Related Report
      1999 Annual Research Report

URL: 

Published: 1999-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi