Optical Resolution Membrane from Main-chin Chiral Polymer
| Project/Area Number |
11650906
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
高分子合成
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| Research Institution | Niigata University |
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Principal Investigator |
AOKI Toshiki Faculty of Engineering, Niigata University, Professor, 工学部, 教授 (80212372)
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| Co-Investigator(Kenkyū-buntansha) |
KANEKO Takashi Faculty of Engineering, Niigata University, Assistant, 工学部, 助手 (90272856)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2000: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1999: ¥2,000,000 (Direct Cost: ¥2,000,000)
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| Keywords | Main-chain Chirality / Asymmmetric Polymerization / Separation Membrane / Optical Resolution / Phenylacetylene |
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| Research Abstract |
1. Synthesis of Main-chain Chiral Polymers
We found main-chain chirality was induced when various kind of acetylene having a bulky chiral substituent. The asymmetric induction was effective when the bulky substituent is close to the main-chain.
2. Syntheses of Chiral Polymers that have the chirality only in the main-chain
To clarify the effect on the enantioselective permeation, we examined synthetic methods of chiral polymers having the chirality only in the main-chain. We were able to synthesize such polymers by polymerization of a hydroxyphenylacetylene with rhodium-chiral amine catalytic system. The resulting polymers had a membrane-forming ability.
3. Optical Resolution by Membranes of Main-chain Chiral Polymers
Membranes from the polymers obtained in 1 showed high enantioselectivity in permeation. The content of the chiral substituent was also found to be important.
4. Optical Resolution by Membranes of Chiral Polymers that have the chirality only in the main-chain
Since membranes from the polymers obtained in 2 showed enantioselectivity in permeation, it was confirmed that time main-chain chirality was effective for the separation. We examined the relationship between the strength of CD signal and the selectivity.
5. Effect of the main-chain chirality on enantioselective permeation
From the results of 3 and 4, The main-chain chiralities were very effective for enantioselective permeation.
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Report
(3 results)
Research Products
(6 results)
