Study on associations between mortality, life-style and fluctuations of time series laboratory tests

Research Project

Project/Area Number	11670376
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Public health/Health science
Research Institution	Nagasaki University
Principal Investigator	KONDO Hisayoshi Division of Scientific Data registry Nagasaki University School of Medicine, Assistant, 医学部, 助手 (00170431)
Co-Investigator(Kenkyū-buntansha)	TOMONAGA Masao Division of Scientific Data registry Nagasaki University School of Medicine, Professor, 医学部, 教授 (40100854) HONDA Sumihisa Department of Radiation Epidemiology Nagasaki University School of Medicine, Assistant, 医学部, 助手 (90244053) MINE Mariko Division of Scientific Data registry Nagasaki University School of Medicine, Assistant Professor, 医学部, 助教授 (00108292) SHIBATA Yoshisada Department of Radiation Epidemiology Nagaski University School of Medicine, Professor, 医学部, 教授 (40010954)
Project Period (FY)	1999 – 2000
Project Status	Completed (Fiscal Year 2000)
Budget Amount *help	¥2,100,000 (Direct Cost: ¥2,100,000) Fiscal Year 2000: ¥1,200,000 (Direct Cost: ¥1,200,000) Fiscal Year 1999: ¥900,000 (Direct Cost: ¥900,000)
Keywords	time series laboratory test / life-style / coefficient of variation / mortality
Research Abstract	Associations between mortality, life-style and time series laboratory tests were investigated using data of medical examination for atomic bomb survivors. Individual mean values and coefficients of variation of laboratory tests during 10 years were calculated for five items, which were red blood cell, white blood cell, hemoglobin, systolic blood pressure and diastolic blood pressure. Without regard to the laboratory test item and the cause of death, the large coefficient of variation of laboratory test increased mortality as well as each mean value of that. These findings indicate that the coefficient of variation of time series laboratory test includes different information for human health from the mean value. Although the number of life-style which showed significant associations with coefficients of variation of time series laboratory tests was two, that of mean values was 10. These results indicate that the life-style associates more strongly individual mean values of laboratory tests than coefficients of variation.