| Project/Area Number |
11670394
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Osaka Medical College |
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Principal Investigator |
WATANABE Takemasa Faculty of Medicine, Osaka Medical College Associate Professor, 医学部, 助教授 (50182928)
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Misuzu Faculty of Medicine, Osaka Medical College Lecturer, 医学部, 講師 (30084924)
DOTE Tomotaro Faculty of Medicine, Osaka Medical College Lecturer, 医学部, 講師 (10257868)
KONO Koichi Faculty of Medicine, Osaka Medical College Professor, 医学部, 教授 (30111016)
USUDA Kan Faculty of Medicine, Osaka Medical College Lecturer, 医学部, 講師 (80298752)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2000: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1999: ¥2,900,000 (Direct Cost: ¥2,900,000)
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| Keywords | Elderly / Living alone / Ambulatory blood pressure variations / Depressive status / Sleep disturbance |
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| Research Abstract |
The objective of the present study was to investigate the relationship among ambulatory blood pressure variations, depressive status and sleep disturbance in community-dwelling elder persons in a rural area. The questionnaire survey was conducted in 2,756 elderly persons aged over 65 who lived at home to clarify characteristics of elderly living alone on depressive status and sleep disturbance, and then 41 elderly volunteers were examined on the depressive status and ambulatory blood pressure variations with sleep-awake judgments by actigraphs. Taking characteristics of lived-alone elderly on depressive status and sleep disturbance into consideration, we obtained results of this study as follows. (1) Both average values of systolic and diastolic blood pressure in subjects with hypertension were higher during an awake-stage and a sleep-stage than without hypertension. (2) There was no significant effect of self-reported sleep disturbance to ambulatory blood pressure variations. (3) The significant correlation was observed between the duration of awake-time by actigraphs and the coefficient of variation in diastolic blood pressure and pulse rate during night sleep. (4) No significant correlation was observed between self-reported depressive conditions and sleep disturbance indices by actigraphs. (5) Hypertensive subjects had less night decrease rate in a diastolic blood pressure in comparison to normotensives. In conclusion, the depressive status and the sleep disturbance may independently associate with ambulatory blood pressure variations in community-dwelling elder persons, and those associations may be modified by the presence of hypertension.
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