| Project/Area Number |
11670406
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Hirosaki University |
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Principal Investigator |
KURODA Naohito Professor, Department of Forensic Medicine, Hirosaki University School of Medicine, 医学部, 教授 (40161799)
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| Co-Investigator(Kenkyū-buntansha) |
SHINOZUKA Tatsuo Assistant Professor, Department of Legal Medicine, Keio University, School of Medicine, 医学部, 講師 (70095610)
MURAI Tatsuya Professor, Department of Legal Medicine, Keio University, School of Medicine, 医学部, 教授 (80129692)
YOSHIOKA Naofumi Professor, Department of Legal Medicine, Akita University, Faculty of Medicine, 医学部, 教授 (80108935)
TANNO Kozo Assistant, Department of Forensic Medicine, Hirosaki University School of Medicine, 医学部, 助手 (20327026)
SANNOHE Seiya Assistant, Department of Forensic Medicine, Hirosaki University School of Medicine, 医学部, 助手 (30312490)
齋藤 一之 埼玉医科大学, 医学部, 教授 (10215535)
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| Project Period (FY) |
1999 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 2002: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2001: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2000: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1999: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | alcohol / interval between alcohol intoxication and death / postmortem examination / vitreous humor / cerebrospinal fluid |
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| Research Abstract |
The possibility of prediction of the interval between the commencing or finishing time and death was surveyed by measuring alcohol concentrations of several body fluids obtained from the autopsy cases examined during the period starting April, 1999 up to and including March, 2003, based upon the principle that absorption, distribution and discharge of ethanol are unequal in the body fluids. The correlation coefficients of ethanol concentrations amongst the cadaveric body fluids of 85 intoxicated fatal cases were as follows; heart blood / femoral venous blood: 0.923, heart blood / urine: 0.848, heart blood / cerebrospinal fluid: 0.926, heart blood / vitreous humor: 0.796, femoral venous blood / urine: 0.860, femoral venous blood / cerebrospinal fluid: 0.905, femoral blood / vitreous humor: 0.905, urine / cerebrospinal fluid: 0.772, urine / vitreous humor: 0.902, cerebrospinal fluid / vitreous humor: 0.872. The tendency that the ratios of blood alcohol concentration(BAC)/vitreous humor alcohol concentration(VHAC) were lower in the cases with shorter intervals between alcohol intoxication and death, whereas they were higher in the cases with the longer intervals, as it was expected. The estimation of the period between alcohol intoxication and death depends on the hypothesis that comparison of two parameters, 1)clear difference of alcohol concentration in several body fluid and 2)clear information about the time of starting or ending alcohol intake, enables the prediction of the interval. Though it was not successful to create nomograms for predicting the interval within a limited period in this study for unexpectedly small number of cases with necessary information, it is expected that a more accurate conclusion will be obtained by a further survey with much more proper cases in the same method.
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