| Project/Area Number |
11670902
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | OITA MEDICAL UNIVERSITY |
|---|
Principal Investigator |
YAMADA Yasunari (2001) Oita Medical University, Department of Radiology, Assistant, 医学部, 助手 (60244183)
堀 雄三 (1999-2000) 大分医科大学, 医学部, 助手 (70295187)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KIYOSUE Hiro Oita Medical University, Department of Radiology, Assistant, 医学部, 助手 (40264345)
MATSUMOTO Shunro Oita Medical University, Department of Radiology, Assistant Professor, 医学部, 助教授 (80219500)
MORI Hiromu Oita Medical University, Department of Radiology, Professor, 医学部, 教授 (20128226)
MIYAKE Hidetoshi Oita Medical University, Department of Radiology, Professor, 医学部, 教授 (20136675)
山田 康成 大分医科大学, 医学部, 助手 (60244183)
|
|---|
| Project Period (FY) |
1999 – 2001
|
| Project Status |
Completed (Fiscal Year 2001)
|
| Budget Amount *help |
¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2001: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2000: ¥500,000 (Direct Cost: ¥500,000)
|
|---|
| Keywords | bile duct cancer / helical CT |
|---|
| Research Abstract |
OBJECTIVE : The purpose of this study is to evaluate of the local spread of lower bile duct cancer with thin-section helical CT in correlation with the surgical and pathological findings.
MATERIALS AND METHODS : From 1999 to 2001, there were 10 cases including 5 males and 5 females with post-surgical diagnosis of lower bile duct cancer at our institution. Thin-section helical CTs were performed with parameters of 5-mm collimation, 5-mm/s table incrementation, and reconstruction at 2.5mm Intervals in 8 cases, and with parameters of 7-mm collimation, 7-mm/s table incrementation, and reconstruction at 3.5mm intervals in 2 cases. Three-phase contrast-enhanced CT scans were obtained at 40s (arterial phase), 70s (portal venous phase), and 150s (delayed phase) after administration of contrast material (Iopamidol 370 mg/ml).
RESULTS : In all 10 cases, the tumors were identified on CT. On the arterial phase, the tumors were hypodense in comparison with the adjacent pancreatic parenchyma in 9 cases and isodense in one case. On the delayed phase, the tumors were hypodense in 2 cases, isodense in 6 cases, and hyperdense in 2 cases. These finding on CT reflected the histological characteristics of the tumors and adjacent pancreatic parenchyma. Vascular invasions were evaluated with contiguity between tumors and vessels. The sensitivity was 100% and the specificity was 97%. Pancreatic invasions were evaluated with mass-pancreas border. The sensitivity was 87.5% and the specificity was 100%. Tumor invasions into the second portion of the extrapancreatic nerve plexus were evaluated with continuity between tumor and superior mesenteric artery (and/or Inferior pancreaticoduodenal artery). The sensitivity and specificity were 100%.
The thin-sectional helical CT is thought to be useful in the evaluation of the local spread of lower bile duct cancer.
|
