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Application of the collision technique and development of fast-recovery preamplifier for detecting conduction delicits in lumbar spinal stenosis.

Research Project

Project/Area Number 11671442
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionKochi Medical School

Principal Investigator

TANI Toshikazu  Kochi Medical School, Dept.of Orthopaedic Surgery, Associate Professor., 医学部, 助教授 (90136250)

Co-Investigator(Kenkyū-buntansha) TAMESADA Tateomi  Tokushima University, Dept.of Technology, Professor., 工学部, 教授 (60035615)
TANIGUCHI Shinichirou  Kochi Medical School, Dept.of Orthopaedic Surgery, Assistant Professor., 医学部, 助手 (00304676)
Project Period (FY) 1999 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2000: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1999: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsLumbar spinal stenosis / Radiculopathy / Electrodiagnosis / Cauda equina action potential / Collision technique / fast-recovery preamplifier
Research Abstract

Clinically recorded lumbosacral evoked potentials after peripheral nerve stimulation are less sensitive than might be expected for a single radicular lesion. Direct nerve root stimulation, despite its potential advantage, is not practical because of an overloading stimulus artifact. A collision technique should circumvent these problems. For a single L-5 radicular lesion produced in rats by constant, localized compression, sequential changes of epidurally recorded potentials after sciatic nerve stimulation (Group 1) or direct L-5 root stimulation (Group 2) were compared to those after a combination of L-6 root and sciatic nerve stimulation (Group 3). At every step of recording, the N1 peak amplitude was significantly smaller in group 2 and 3 than in group 1, whereas there was no significant difference between group 2 and 3. Thus, the collision technique in gourp 3 achieved nearly the same diagnostic yield as the direct L5 root stimulation in group 2 by blocking the unwanted impulses transmitted via the L6 root.
In clinical practice, unlike animal experiments, it is difficult to control the stimulus artifact by shielding the stimulator from the surrounding tissues and thereby reducing spread of stimulus current. To circumvent this problem, we developed a fast-recovery preamplifier. This preamplifier interposed between the recording electrodes and the amplifier allows opening the conduction path at the moment of large stimulus input and closing the path with the wane of its magnitude. The printed circuit plate of the preamplifier was made of glass epoxy because of an excellent high frequency specificity of the material. It was shielded from the outside electric noise by being doubly encased in two aluminum boxes. In addition, the electric noise occurring when the switch closes and opens was minimized by using the MCD-5221 switch.

Report

(3 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • Research Products

    (9 results)

All Other

All Publications (9 results)

  • [Publications] Taniguchi S: "Mini-symposium ; Lumbar spinal canal slenosis, (iii) Decompression surgery for lumbar spinal stenosis."Current Orthop. 13. 184-190 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Tani T: "Sequential changes of orthodromie sensory nerve action potentials induced by experimental compression of the median nerve at the wrist."Clin Neurophysiol. 112. 136-144 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 谷口愼一郎: "NEW MOOK整形外科 NO.9"金原出版. 347 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Taniguchi S.: "Mini-symposium ; Lumbar spinal canal stenosis, (iii) Decompression surgery for lumbar spinal stenosis"Current Orthop. 13. 184-190 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Tani T.: "Sequential changes of orthodromic sensory nerve action potentials induced by experimental compression of the median nerve at the wrist."Clin Neurophysiol. 112. 136-144 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Tani T: "Sequential changes of orthodromic sensory nerve action potentials induced by experimental compression of the median nerve at the wrist."Clin Neurophysiol. 112. 136-144 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Tani T: "Intraoperative electroneurography in the assessment of the level of operation for cervical spondylotic myclopathy in the elderly."J Bone Joint Surg. 82-B. 269-274 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Tani T: "Advances in Clinical Neurosciences 2000"Eastern zone CME Ranchi. 467 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Tani T: "Electrophysiology and Kinesiology"Monduzzi Editore. 689 (2000)

    • Related Report
      2000 Annual Research Report

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Published: 1999-04-01   Modified: 2016-04-21  

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