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Analysis of cauda equina compression in lumobar spinal stenosis

Research Project

Project/Area Number 11671451
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionSaitama Medical School

Principal Investigator

TAKAHASHI Keisuke  Saitama Medical School, Professor, 医学部, 助教授 (90179482)

Co-Investigator(Kenkyū-buntansha) WATANABE Yasuyuki  Saitama Medical School, Assistant, 医学部, 助手 (70327055)
HIRASAWA Youichiro  Saitama Medical School, Assistant, 医学部, 助手 (60286086)
宇南山 賢二  埼玉医科大学, 整形外科, 助手 (20296247)
Project Period (FY) 1999 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 2001: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2000: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1999: ¥1,700,000 (Direct Cost: ¥1,700,000)
Keywordslumbar apine / spinal stenosis / intermittent claudication / epidural pressure / the elderly / posture / walking / exercise / 圧迫力 / 腰部脊柱管狭窄症 / 神経圧迫動態 / 圧測定
Research Abstract

The study of epidural pressure measurements clearly demonstrated that the local extradural pressure at the stenotic level was changed by motion in patients with spinal stenosis. The pressure was low in lying and sitting, and high in standing. Especially, the pressure was increased by lumbar extension, but decreased by forward flexion. Changes of the epidural pressure correlated with the occurence of clinical symptoms of nerve roots compression. These pressure changes may explain the postural dependency of symptoms in spinal stenosis
The epidural pressure was also changed at walking in patients with neurogenic intermittent claudication. The epidural pressure change had a pattern of increase and decrease, and this pattern was repeated during walking. The epidural pressure was high at simple walking and low at walking with lumbar flexion. Intermittent compression to the nerve roots during walking might have a important role in the pathogenesis of neurogenic intermittent claudication
The pressure was extremely increased by trunk muscle exercises e. g. back muscle strength exercise. This result imply that back muscle exercise might be dangerous for patients with lumbar spinal stenosis
In conclusion, static compression in lumbar spinal stenosis is low compared to lumbar disc herniation. Dynamic compression by lumbar motion would be important for the pathophysiology of lumbar spinal stenosis

Report

(4 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report

Research Products

(17 results)

All Other

All Publications (17 results)

  • [Publications] 高橋啓介: "腰部脊柱管狭窄症の病態、馬尾の機能的圧迫から"現代医療. 33. 23-27 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 高橋啓介: "腰部脊柱管狭窄症の病態と診断-2"日本整形外科学会雑誌. 74(5). S233 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 高橋啓介ほか: "硬膜外圧からみた馬尾性間欠跛行"骨・関節・靭帯. 12(4). 377-381 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Keisuke Takahashi, et al.: "Nerve root pressure in lumbar disc herniation"Spine. 24(19). 2003-2006 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 高橋啓介: "腰部脊柱管狭窄症(分担:硬膜外圧からみた病態:p53 59)"金原出版. 347 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Keisuke Takahashi, et al: "Pathophysiology of cauda equina compression"Gendaiiryou. 33. 23-27 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Keisuke Takahashi: "Pathology and diagnosis of lumbar spinal stenosis-2"J Jap Orthop Asoc. 74(5). S233 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Keisuke Takahashi, et al: "Dynamics of cauda equina compression in lumber spinal stenosis"Mechanical Loading of Bones and Joints. Springer. 237-243 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Keisuke Takahashi: "Cauda equina intermittent claudication in view of the epidural pressue"Kotu-Kansetu-Jintai. 12(4). 377-381 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Keisuke Takahashi, et al: "Nerve root presure in lumbar disc herniation"Spine. 24(19). 2003-2006 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 高橋啓介ほか: "腰部脊柱管狭窄症の病態、馬尾の機能的圧迫から"現代医療. 33. 23-27 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 高橋 啓介: "腰部脊柱管狭窄症(分担:硬膜外圧からみた病態:p53-59"金原出版. 347 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 高橋啓介: "硬膜外圧からみた馬尾性間欠跛行"骨・関節・靭帯. 12(4). 377-381 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Keisuke Takahashi, et al: "Nerve root pressure in lumbar disc herniation"Spine. 24(19). 2003-2006 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] 高橋啓介: "腰部脊柱管狭窄症の病態と診断-2"日本整形外科学会雑誌. 74(5). S233 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Keisuke Takahashi: "Mechanical Loading of Bones and Joints (chapter)"Springer. 315 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] 高橋啓介: "腰部脊柱管狭窄症(分担執筆)"金原出版. 347 (2001)

    • Related Report
      2000 Annual Research Report

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Published: 1999-03-31   Modified: 2016-04-21  

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