Neuronal mechanisms of bilateral hearing in hearing impaired human subjects
| Project/Area Number |
11671678
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Osaka University |
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Principal Investigator |
TAKAHASHI Yoshifumi Osaka University, Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 (80283779)
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| Co-Investigator(Kenkyū-buntansha) |
KUBO Takeshi Osaka University, Graduate School of Medicine, Professor, 医学系研究科, 教授 (30107031)
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| Project Period (FY) |
1999 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2001: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2000: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1999: ¥2,800,000 (Direct Cost: ¥2,800,000)
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| Keywords | binaural hearing / hearing impaired subjects / cochlear implant / hearing aids / HINT Japanese / quiet and noisy circumstances / 言語聴取能 / 雑音負荷 / 両耳装用効果 / 音源定位 / 上立 / ITD / 細胞外記録 / 層状核 / ヤキセイインコ / セキセイインコ / Laminaris / 聴覚 / 細胞内記録 |
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| Research Abstract |
Single unit recording in the cochlear nucleus of owl have been done by Saberi and Takahashi (2002). We found that an appropriate time difference of input sound caused the excitation of cochlear neurons, but less excitation was resulted by different time sequences. Information of sound arrival difference was conducted into the superior colliculus and direction of sound source was detected.
The benefit of binaural hearing has been extensively investigated in human subjects. However, little is known for such mechanisms in hearing impaired subjects. In the preliminary study, we examined the binaural hearing mechanisms in subjects who weared cochlear implant (CI) in one ear and the hearing aid (HA) on the other side (Iwaki and Kubo, 2000).
Hearing in Noise Test (HINT), which was developed by Nilsson and Soli (1994), has been widely used in USA to examine the speech detection ability under quiet and noisy circumstances. We made this test using Japanese language with the cooperation of Soli (HINT-J: Shiroma et al., 2002). Using HINT-J the speech perception ability was examined under the quiet and noisy conditions. There was no significant difference in speech perception under quiet condition when CI alone and HA+CI conditions were compared. But a significant difference was found under noisy condition between these two conditions. Although characteristics of input sound should be different between two ears (CI vs HA), the additional effects was detected in our hearing impaired subjects.
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Report
(4 results)
Research Products
(8 results)
