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Neuronal mechanisms of bilateral hearing in hearing impaired human subjects

Research Project

Project/Area Number 11671678
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionOsaka University

Principal Investigator

TAKAHASHI Yoshifumi  Osaka University, Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 (80283779)

Co-Investigator(Kenkyū-buntansha) KUBO Takeshi  Osaka University, Graduate School of Medicine, Professor, 医学系研究科, 教授 (30107031)
Project Period (FY) 1999 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2001: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2000: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1999: ¥2,800,000 (Direct Cost: ¥2,800,000)
Keywordsbinaural hearing / hearing impaired subjects / cochlear implant / hearing aids / HINT Japanese / quiet and noisy circumstances / 言語聴取能 / 雑音負荷 / 両耳装用効果 / 音源定位 / 上立 / ITD / 細胞外記録 / 層状核 / ヤキセイインコ / セキセイインコ / Laminaris / 聴覚 / 細胞内記録
Research Abstract

Single unit recording in the cochlear nucleus of owl have been done by Saberi and Takahashi (2002). We found that an appropriate time difference of input sound caused the excitation of cochlear neurons, but less excitation was resulted by different time sequences. Information of sound arrival difference was conducted into the superior colliculus and direction of sound source was detected.
The benefit of binaural hearing has been extensively investigated in human subjects. However, little is known for such mechanisms in hearing impaired subjects. In the preliminary study, we examined the binaural hearing mechanisms in subjects who weared cochlear implant (CI) in one ear and the hearing aid (HA) on the other side (Iwaki and Kubo, 2000).
Hearing in Noise Test (HINT), which was developed by Nilsson and Soli (1994), has been widely used in USA to examine the speech detection ability under quiet and noisy circumstances. We made this test using Japanese language with the cooperation of Soli (HINT-J: Shiroma et al., 2002). Using HINT-J the speech perception ability was examined under the quiet and noisy conditions. There was no significant difference in speech perception under quiet condition when CI alone and HA+CI conditions were compared. But a significant difference was found under noisy condition between these two conditions. Although characteristics of input sound should be different between two ears (CI vs HA), the additional effects was detected in our hearing impaired subjects.

Report

(4 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] Saberi K, Takahashi Y, Farahbod H, Konishi M.: "Neural basis of and auditory illusion and its elimination in owls."Nature Neuroscience. 2. 656-659 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Saberi K, Takahashi Y, Egnor R, Farahbod H, Mazer J, Konishi M.: "Detection of large interaural delays and its implication for models of binaural interaction"JARO. 3. 80-88 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 松代直樹, 佐藤崇, 井脇貴子, 土井勝美, 久保武: "人工内耳と補聴器の両耳装用における両耳聴効果について"日耳鼻. (印刷中). (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 井脇貴子, 久保武: "大阪府感覚器難病研究会報告書"353 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Shiroma M, Iwaki T, Kubo T.: "In Cochlear implants an update (Eds. T Kubo, Y Takahashi, T Iwaki)"Kugler (Hague). 594 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Saberi K, Takahashi Y, Farahbod H, Konishi M: "Neural basis of and auditory illusion and its elimination in owls"Nature Neuroscience. 2. 656-659 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Saberi K, Takahashi Y, Egnor R, Farahbod H, Mazer J. Konishi M: "Detection of large interaural delays and its implication for models of binaural interaction"JARO. 3. 80-88 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Shiroma M, Iwaki T, Kubo T: "Development of hearing in noise test (HINT) in Japanese"In Cochlear implants an update (Eds. T Kubo, Y Takahashi, T Iwaki)(Kugler (Hague)). 209-211 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary

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Published: 1999-04-01   Modified: 2016-04-21  

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