| Budget Amount *help |
¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 2001: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2000: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1999: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Research Abstract |
There is different physical chemistry-character between crystalline and amorphous substance. This study aimed at developing a high amorphous calcium phosphate-collagen complex material of living body affinity using this character. It was suggested that the collagen type I which has calcification ability from a precedence experiment differs from the collagen type I which is not calcified in points, such as bridge construction. Therefore, development of the bridge construction analyzing method of collagen was also united and tried. A part of the result was released as "heat analytic research of softening dentine", "examination about the influence which demineralization processing does to the quality of dentine organic, especially collagen", and "research of a collagen type I heat decomposition process." Moreover, we pursued about the crystalline high enamel apatite most as part [ the characteristic of a living body apatite ] of research, and decided to aim at evaluation of living body co
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nformity, such as apatite joint ability, based on the knowledge. Therefore, "method by the size of an enamel crystal and the integration width of the presumed-X-rays diffraction peak [ lattice ] of disorder -", "presumption of the carbonic acid ion distribution ratio under apatite crystal by a man's enamel specific gravity part drawing and a content water ratio", "examination of disorder of the size of an enamel crystal and a *attice by the integration width of an X ray diffraction peak", etc. were studied. In order to measure the influence of an in plant to a living body, the cell culture experiment and the animal experiment were conducted. Those results "Potential application of micro-CT for study of bone-Ti implant interface", "Application of high resolution micro focus X-ray CT for the observation of human tooth", It announced as "Histo-pathological study of bone formation using porous hydroxyapatite-BMP composite in dog jaw bone defect." The amorphous usefulness as a biomechanical material was suggested from these results. In the future, establishment and the applied research of the manufacturing technique of this composite material are pointed out as a subject. Less
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