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Examination of Exercise Program for Improvement of Age-Related Decreases in Muscle Strength

Research Project

Project/Area Number 11680025
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 体育学
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

ISHIHARA Akihiko  Kyoto Univ., Fac.Integr.Human Stud., Assoc.Prof., 総合人間学部, 助教授 (90184548)

Project Period (FY) 1999 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥3,800,000 (Direct Cost: ¥3,800,000)
Fiscal Year 2000: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1999: ¥2,900,000 (Direct Cost: ¥2,900,000)
Keywordsold age / exercise program / muscle strength / exercise intensity / muscle atrophy
Research Abstract

The purpose of this study was to examine exercise program for improvement of an age-related decrease in muscle strength. Eighty-week-old male rats(n=10)were exercised for 10 weeks with vluntary running wheefs attached to the cage. Load for the wheel were increased according to the daily running distance of each animal. After the exercise period, the soleus and plantaris muscles were removed and frozen in liquid nitrogen. Serial transverse sections, 10 μm thick, were cut and stained for ATPase and SDH activities for muscle fiber type classification and measurement of fiber SDH activity. All types of fibers in the soleus muscle showed hypertrophy after the exercise. Fast type of fibers at the superficial region in the plantaris muscle showed hypertrophy after the exercise. The results indicate that selective recruitment of fast type of fibers causes during the maximum muscle contraction at old ages, and that such an exercise inhibits an age-related muscle fiber atrophy.

Report

(3 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report

URL: 

Published: 1999-04-01   Modified: 2016-04-21  

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