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Effects of food intake during pregnancy and lactation upon the bone metabolism and bone mineral density---intervention study

Research Project

Project/Area Number 11680131
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 食生活
Research InstitutionNara University of Education

Principal Investigator

YONEYAMA Kyoko  Nara University of Education, Education, Professor, 教育学部, 教授 (30079743)

Co-Investigator(Kenkyū-buntansha) IKEDA Junko  Kyoto Bunkyo College, Home Economics, Professor, 家政学部, 教授 (30076880)
Project Period (FY) 1999 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 2001: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2000: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1999: ¥1,200,000 (Direct Cost: ¥1,200,000)
KeywordsBone density / Maternal food intakes / pregnancy / lactation / Protein intakes / Ultrasound bone densitometry / Maternal health / 介入研究 / 授乳 / 母乳栄養 / 超音波骨密度測定法
Research Abstract

To examine the effectiveness of food intake in preventing bone mineral loss in pregnant and lactating women, considering bone metabolism., 45 pregnant women, two groups of lactating women---one with an enhanced calcium intake, Group M) and the other with diet taking no cow's milk and no milk product (Group N)--- and a control group of non-lactating postpartum women were studied. Dietary food intake based on the mean of the three 24-h dietary recalls for each individual. Bone mineral density (BMD) was measured by ultrasonic bone densitometry. BMD and bone metabolic markers in urine and serum were measured from early pregnancy, at six-month intervals for a maximum of two years.
The results were as follows :
1.The extent of bone loss ratio associated with pregnancy were negatively influenced by parity and protein intakes and positively associated by a dietary ratio of calcium to protein.
2.After lactating for one year, N group had significant decrease in BMD in both 1 and 2 of parity, whereas M group had no significant change.
3.In N group compared with M group, urinary Hydroxyproline/Creatinine ratio was significantly higher at the initial measurement and half a year after, while urinary Ca/Creatinine ratio was significantly lower one year after.
Bone loss by lactation can be prevented with adequate dietary Ca intake.

Report

(4 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (5 results)

All 2000 1999 Other

All Journal Article (3 results) Publications (2 results)

  • [Journal Article] 妊娠中の母体の骨密度変化および骨密度と胎児発育との関係2000

    • Author(s)
      米山京子, 池田順子
    • Journal Title

      日本公衆衛生雑誌 47

      Pages: 661-669

    • NAID

      10008643137

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Journal Article] 妊娠、授乳期の骨密度の意義-母子間におけるカルシウム動態の巧妙な仕組み1999

    • Author(s)
      米山京子
    • Journal Title

      家庭科教育 73

      Pages: 41-46

    • NAID

      40000503821

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Journal Article] 授乳婦の骨密度に及ぼす授乳と食生活の影響-前向き研究-1999

    • Author(s)
      米山京子
    • Journal Title

      母性衛生 40(4)

      Pages: 473-481

    • NAID

      10013805009

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 米山京子, 池田順子: "妊娠および授乳後の骨密度の回復-縦断研究"日本公衆衛生雑誌(印刷予定). 49巻 号(未定). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 米山京子,池田順子: "妊娠中の母体の骨密度変化および骨密度と胎児発育との関係"日本公衆衛生雑誌. 47・8. 661-669 (2000)

    • Related Report
      2000 Annual Research Report

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Published: 1999-04-01   Modified: 2016-04-21  

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