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Development on evaluation method of thought and personality disorders based on quantitative individuality of language behavior and brain functional information

Research Project

Project/Area Number 11680836
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionUniversity of Tokyo

Principal Investigator

ITOH Kenji  University of Tokyo, Graduate School of Medicine, Assist Prof, 大学院・医学系研究科, 助手 (80010106)

Co-Investigator(Kenkyū-buntansha) HIRAMATSU Kenichi  University of Ryukyu, Faculty of Medicine Hospital, Assoc Prof, 医学部・附属病院, 助教授 (50218814)
YUMOTO Masato  University of Tokyo, Faculty of Medicine Hospital, Assist Prof, 医学部・附属病院, 助手 (30240170)
IWANAMI Akira  University of Tokyo, Faculty of Medicine Hospital, Assoc Prof, 医学部・附属病院, 助教授 (80276518)
NAKAGOME Kazuyuki  Showa University, Faculty of Medicine Hospital, Assoc Prof, 医学部・附属病院, 助教授 (30198056)
KOSHIDA Ichiro  Tokyo University of Technology, Faculty of Engng, Assoc Prof, 工学部, 助教授 (00192055)
福田 正人  群馬大学, 医学部・附属病院, 助教授 (20221533)
Project Period (FY) 1999 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2000: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 1999: ¥2,200,000 (Direct Cost: ¥2,200,000)
KeywordsIndividuality / Electroencephalography / Magnetoencephalography / Speech / Face expression / Dialogue / Personality disorders / Social skill Training / 生活技能訓錬 / トポグラフィー
Research Abstract

We investigated and got following results on the development of objective evaluation method for thought and personality disorders as well as for treatments including SST(social skill training)based on four types of personality-related data, i.e., brain activity data, results from mental test, behavioral pattern in dialogue, cognitive impression on mental states emerged from subjects.
extraction method of individuality in spoken language and thought process.
1. We analyzed brain metabolic data from blood metabolities of neuromodulators as candidates of individuality.
2. We extracted individuality in multi-channel EEG and MEG topographies which are related to linguistic and thought process.
3. We measured diagnostic behaviors of thought and personality disordered patients in treatments.
4. We found individuality and abnormality in MR images of cortico-subcortical system.
5. We improved mental and psychological tests to be a computer-controlled testing system with simultaneous measuring of brain functional images.
6. We developed a method for extracting individualities from multi-channel EEG and MEG data as well as from speech and body expression.
7. We presented a model on individuality on the basis of contributions of neurotransmitters and modulators projected to cerebro-celebellar system.
8. We applied cross-correlation analysis on speech and body movements to quantify diagnostic characteristics and disordered patterns.
9. We constructed a integrated database of brain functional and behavioral data in tests and treatments to apply subjective and quantified evaluation of thought and personality disorders.

Report

(3 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • Research Products

    (30 results)

All Other

All Publications (30 results)

  • [Publications] Itoh K, Yumoto M, Uno A, Kurauchi T, Kaga K: "Temporal stream of cortical representation for auditory spatial localization in human hemispheres"Neuroscience Letter. 292. 215-219 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Itoh K, Yumoto M, Uno A, Kurauchi T, Kaga K: "Topographic differences of auditory middle -latency responses to binaural images"Clinical Neurophysiology. 111. S137-S137 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Koshida I, Itoh K, Kasai K, Iwanami A, Niwa S, et al: "Coherence analysis of functional modules in cognitive and linguistic process"Clinical Neurophysiology. 111. S18-S18 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 越田一郎,伊藤憲治,畑哲信,岩波明,丹羽真一,他: "脳機能情報を用いたパーソナリティおよび思考とその障害の計算機支援評価法の開発"電気学会医用・生体工学研究会資料. MBE-01. 13-18 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 越田一郎,馬塚れい子,伊藤憲治,笠井清登,岩波明,他: "思考・言語過程における機能モジュールと相関解析(2)"電子情報通信学会技術研究報告. TL00. 1-8 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 越田一郎,伊藤憲治,笠井清登,岩波明,畑哲信,丹羽真一: "動画による対話分析・精神分裂病診断・治療に向けて"電子情報通信学会2001年総合大会講演論文集. ESS1. 276-276 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Nakayama M, Mazuka R, Itoh K, Kondo M, et al: "East Asian Language Processing"CSLI, Stanford University ; Stanford (to appear). (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Itoh K, Yumoto M, Uno A, Kurauchi T, Kaga K: "Temporal stream of cortical representation for auditory spatial localization in human hemispheres"Neuroscience Letter. 292. 215-219 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Itoh K, Yumoto M, Uno A, Kurauchi T, Kaga K: "Topographic differences of auditory middle-latency responses to bunaural images"Clinical Neurophysiology. 111. S137-S137 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Koshida I, Itoh K, Kasai K, Iwanami A, Niwa S, et al: "Coherence analysis of functional modules in cognitive and linguistic process"Clinical Neurophysiology. 111. S18-S18 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Koshida I, Itoh K, Kasai K, Iwanami A, Niwa S, et al: "Brain functional information for computer-assisted evaluation of personality, thought and their disorders"Research Report of IE. MBE-01. 13-18 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Koshida I, Mazuka R, Itoh K, Iwanami A, Niwa S, et al: "Networking and correlation analysis for brain functional data(2)"Technical Report of IEICE. TL00. 1-8 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Koshida I, Itoh K, Kasai K, Iwanami A, Niwa S, et al: "Brain functional information for computer-assisted evaluation of personality, thought and their disorders"Research Report of IE. MBE-01. 13-18 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Koshida I, Mazuka R, Itoh K, Iwanami A, Niwa S, et al: "Networking and correlation analysis for brain functional data(2)"Technical Report of IEICE. 100. 1-8 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Koshida I, Itoh K, Kasai K, Iwanami A, Niwa S, et al: "Analysis of video captured dialog-towards diagnosis and care of schizophrenia"Proc 2001 General Conf IEICE ESS1. 276-276 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Nakayama M, Mazuka R, Itoh K, Kondo M, et al: "East Asian Language Processing"CSLI, Stanford University, Stanford, (to appear). (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Itoh K,Yumoto M,Uno A,Kurauchi T,Kaga K: "Temporal stream of cortical representation for auditory spatial localization in human hemispheres"Neuroscience Letter. 292. 215-219 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Itoh K,Yumoto M,Uno A,Kurauchi T,Kaga K: "Topographic differences of auditory middle-latency responses to binaural images"Clinical Neurophysiology. 111. S137-S137 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Koshida I,Itoh K,Kasai K,Iwanami A,Niwa S, et al: "Coherence analysis of functional modules in cognitive and linguistic process"Clinical Neurophysiology. 111. S18-S18 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 笠井清登,畑哲信,岩波明,中込和幸,伊藤憲治,越田一郎 他: "高解像度脳波計を用いた精神分裂病における純音性・言語性MMNmの検討"臨床神経生理学. 28. 174-174 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 越田一郎,伊藤憲治,笠井清登,畑哲信,岩波明,丹羽真一 他: "脳機能情報を用いたパーソナリティおよび思考とその障害の計算機支援評価法の開発"電気学会医用・生体工学研究会資料. MBE-01. 13-18 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] 越田一郎,馬塚れい子,伊藤憲治,笠井清登,岩波明,中込和幸 他: "思考・言語過程における機能モジュールと相関解析(2)"電気情報通信学会技術研究報告. TL00(發表予定). (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] 越田一郎,伊藤憲治,笠井清登,岩波明,畑哲信,丹羽真一: "動画による対話分析-精神分裂病診断・治療に向けて-"電子情報通信学会2001年総合大会講演論文集. ESS1. 276-276 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Nakayama M,Mazuka R,Itoh K,Kondo M, et al: "East Asian Language Processing"CSLI,Stanford University ; Stanford (to appear). (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kasai K,Nakagome K,Itoh K,Koshida I et al.: "Electrophysiological evidence for sequential activation of multiple brain regions during the auditory selective attention process in humans"Neuro Report. 10. 3837-3842 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Kasai K,Nakagome K,Itoh K,Koshida I,et al.: "Multiple generators in the auditory automatic discrimination process in humans"NeuroReport. 10. 2267-2272 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 笠井清澄、畑哲信、福田正人、中込和幸、平松謙一、伊藤憲治、他: "多チャンネル(128ch)脳波計による Nd の頭皮上分布の検討(第2報)"脳波と筋電図. 27. 158-158 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 笠井清澄、畑哲信、福田正人、中込和幸、平松謙一、伊藤憲治、他: "多チャンネル(128ch)脳波計による MMN の頭皮上分布の検討(第2報)"脳波と筋電図. 27. 158-158 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 越田一郎、伊藤憲治、笠井清澄、畑哲信、福田正人、他: "多成分相関情報解析表示システム"脳波と筋電図. 27. 134-134 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 中込和幸、高沢悟、菅野道、伊藤憲治、越田一郎: "多チャンネル(64ch)脳波計を用いた言語処理に伴う ERP 成分の検討"脳波と筋電図. 27. 139-140 (1999)

    • Related Report
      1999 Annual Research Report

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Published: 1999-04-01   Modified: 2016-04-21  

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