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Structural Connectivity In White Matter Using the MR Diffusion Tensor Imaging

Research Project

Project/Area Number 11680842
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionNARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Principal Investigator

MINATO Kataro  NARA INSTITUTE OF SCIENCE AND TECHNOLOGY, Information Technology Center, Professor, 情報科学センター, 教授 (00127143)

Co-Investigator(Kenkyū-buntansha) YUNEKURA Yushiharu  FUKUI MED.UNIV., High Energy Medical Research Center, Professor, 高エネルギー医学研究センター, 教授 (60135572)
SUGA Nara  INSTITUTE OF SCIENCE AND TECHNOLOGY, Information Technology Center, Instructor, 情報科学センター, 助手 (00294281)
Project Period (FY) 1999 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2000: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1999: ¥2,200,000 (Direct Cost: ¥2,200,000)
KeywordsMRI / MR diffusion Imaging / diffusion tensor / connectivity of white matter / symmetry
Research Abstract

MR diffusion tensor Imaging (DTI) has become a powerful tool for analyzing the structure of brain white matter.
The purpose of this study is to obtain a quantitative map of white matter connectivity in vivo using diffusion tensor properties.We have proposed a method for detecting nerve fiber bundles in white matter using MR diffusion tensor images and have applied the method to in vivo brain measurements.
Although there are many methods to investigate the connectivity of white matter that are based on principal eigenvector or full tensorpropagation. In the proposed method, we use directional diffusion measurements to infer regional white matter connectivity.To assess the connectivity, we compose the map based on the projected tensor distance, then we put a label on the constructed map and segmentregionally connected white matter using labels.
Then we proposed a new method in order to measure a degree of symmetry on the brain structure and showed a prel iminary result of structural un-symmetry between right and left Temporal lobes.

Report

(3 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] 佐藤哲大,湊小太郎,定藤規弘,米倉義晴: "MR拡散テンソル画像を用いた脳内白質神経束の抽出"電子情報通信学会論文誌. J83-D-II. 191-198 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 佐藤哲大,湊小太郎,定籐規弘,岡田知久,米倉義晴,椛沢宏之: "脳内白質神経繊維束の結合度解析"電子情報通信学会技術研究報告、MBE99-154. 99-687. 55-60 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 大友敦,佐藤哲大,菅幹生,湊小太郎,岡田知久,定藤規弘,米倉義晴: "MR拡散テンソル画像を用いた対称性による神経束の定量的評価の試み"電子情報通信学会技術研究報告、MI2000-39. 100-464. 7-10 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] T.Sato,K.Minato,N.Sadato,Y.Yonekura,H.Kabasawa: "Enhancement of Nerve Bundles in White Matter Using MR Diffusion Tensor Maps"IEEE MIC'99. M3-115 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] T.Sato,K.Minato,N.Sadato,T.Okada,Y.Yonekura and H.Kabasawa: "Quantitative Analysis for the Connectivity of Nerve Bundles Using MR DTI"World Congress on Medical Physics and Biomedical Engineering Chicago2000. TH-Aa301-7 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] T.Sato,K.Hasan,A.L.Alexander,K.Minato: "Structural Connectivity in White Matter Using the Projected Diffusion-Tensor Distance"MEDINFO 2001. (発表予定). (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] T.Sato, K.Minato, N.Sadato, Y.Yonekura, H.Kabasawa: "Detection of Human White Matter Fiber Bundles Using MR Diffusion Tensor Images (in Japanese)"IEICE D-II. Vol.183. 191-198 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] T.Sato, K.Minato, N.Sadato, T.Okada, Y.Yonekura, H.Kabasawa: "Analysis for the Connectivity of Nerve Bundles in With Matter (in Japanese)"IEICE MBE99-154. 55-60 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] A.Otomo, T.Sato, M.Suga, M.Minato, T.Okada, N.Sadato, Y.Yonekura: "Symmetry Axis Detection of MR Diffusion Tensor Images (in Japanese)"IEICE MI2000-39. 7-10 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] T.Sato, K.Minato, N.Sadato, Y.Yonekura, H.Kabasawa: "Enhancement of Nerve Bundles in White Matter Using MR Diffusion Tensor Maps."IEEE MIC'99. M3-115 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] T.Sato, K.Minato, N.Sadato, T.Oakda, Y.Yonekura, H.Kabasawa: "Quantitative Analysis for the Connectivity of Nerve Bundles Using MR DTI."World Congress on Medical Physics and Biomedical Engineering Chicago 2000. TH-Aa301-7. (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] T.Sato, K.Hasan, A.L.Alexander, K.Minato: "Structural Connectivity in White Matter Using the Projected Diffusion-Tensor Distance."MEDINFO 2001. (in printing).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 佐藤哲大,湊小太郎,定籐則弘,米倉義晴 他: "MR拡散テンソル画像を用いた脳内白質神経束の抽出"電子情報通信学会 論文誌 D-II. J83・1. 191-198 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 大友敦,佐藤哲大,菅幹生,湊小太郎,岡田知久,定籐則弘,米倉義晴: "MR拡散テンソル画像を用いた対称性による神経束の定量的評価の試み"電子情報通信学会技術研究報告書 MI(医用画像)2000-39. 100・464. 7-10 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] T.Sato,K.Minato and others: "Structual Conectivity in White Matter Using the Projected Diffusion-Tensor Distance"Proc.of MEDINFO 2001. (発表予定).

    • Related Report
      2000 Annual Research Report
  • [Publications] 佐藤哲大、湊小太郎、定藤規弘、米倉義晴、椛沢宏之: "MRI拡散テンソル画像を用いた脳内白質神経束の抽出"電子情報通信学会 論文誌D-II. J83,No.1. 191-198 (2000)

    • Related Report
      1999 Annual Research Report

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Published: 1999-04-01   Modified: 2025-11-20  

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