| Project/Area Number |
11691164
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Obihiro University of Agriculture and Veterinary Medicine (2000-2001)
Hokkaido University (1999) |
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Principal Investigator |
SUGIMOTO Chihiro Obihiro University of Agriculture and Veterinary Medicine, National research Center for Protozoan Diseases, Professor, 原虫病研究センター, 教授 (90231373)
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| Co-Investigator(Kenkyū-buntansha) |
INOUE Noboru National research Center for Protozoan Diseases, Professor, 原虫病研究センター, 講師 (10271751)
FUISAKI Kozo National research Center for Protozoan Diseases, Professor, 原虫病研究センター, 教授 (00292095)
NAGASAWA Hideyuki National research Center for Protozoan Diseases, Professor, 原虫病研究センター, 教授 (60172524)
FUKISHI Hideto Gifu University , Associate Professor, 農学部, 助教授 (10156763)
TAKAI Shinji Kitasato Universty, Associate Professor, 獣医畜産学部, 助教授 (80137900)
大橋 和彦 北海道大学, 大学院・獣医学研究科, 助手 (90250498)
小沼 操 北海道大学, 大学院・獣医学研究科, 教授 (70109510)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥11,700,000 (Direct Cost: ¥11,700,000)
Fiscal Year 2000: ¥5,300,000 (Direct Cost: ¥5,300,000)
Fiscal Year 1999: ¥6,400,000 (Direct Cost: ¥6,400,000)
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| Keywords | Theileria / Babesia / Protozoan diseases / wildlife / phylogeny / herpesvirus / Rhodococcus / rRNA gene / 原虫 / 馬ヘルペスウイルス / Rhodococcus equi / 住血原虫 |
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| Research Abstract |
Some of pathogens are communicable among humans, domesticated and wild animals and cause various diseases. In this study, we investigated protozoan, bacterial and vial pathogens from wild or domestic animals and their environment in order to determine whether they can acquire new host range by crossing biological and environmental barriers.
Theileria parasite in ruminants are devided into highly pathogenic and apathogenic species. Wildlife harbor parasites of both categories, but they are not closely related to those from domestic animals on the basis of ribosomal RNA gene analysis. Rhodococcus equi with virulent plasmid are isolated from soil in horse farms, but the plasmid types are similar to those isolated in isolate from European horses. Therefore, pathogenic strains of R. equi may have been brought from Europe and colonized in soil in Africa. Herpesviruses were demonstrated in blood samples on 5 species of antelopes and rhinocerous. The isolate from impala is different from those isolated from domestic ruminants.
Taken together, it is concluded that pathogens investigated in this study have been associated and coevolved with their original hosts, and that they are not easily able to acquire new host even under environments where wildlife and domestic animals are in close contact with each other.
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