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Study on advanced optical coherence tomography

Research Project

Project/Area Number 11792004
Research Category

Grant-in-Aid for University and Society Collaboration

Allocation TypeSingle-year Grants
Research Field Applied optics/Quantum optical engineering
Research InstitutionYamagata University

Principal Investigator

TANNO Naohiro  Yamagata University, Graduate school of science and engineering, Professor, 大学院・理工学研究科, 教授 (00006248)

Co-Investigator(Kenkyū-buntansha) SATO Manabu  Yamagata University, Graduate school of science and engineering, Associate Professor, 大学院・理工学研究科, 助教授 (50226007)
船場 忠幸  山形大学, 大学院・理工学研究科, 助手 (30238654)
Project Period (FY) 1999 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥6,100,000 (Direct Cost: ¥6,100,000)
Fiscal Year 2001: ¥6,100,000 (Direct Cost: ¥6,100,000)
Keywordsoptical coherence tomography / high spatial resolution / synthesized light source / stability of heterodyne beat signal / Compact interferometer / simultaneous measurements of velocity vector and image / 生体断層画像 / 光学干渉系 / インコヒーレント光源 / コヒーレンス / 空間分解能 / スペクトル幅 / コヒーレンス光源 / コヒーレント / 共焦点光学系 / コヒーレント光源
Research Abstract

The objects of this study are a)The research and developments for the enhancement of a spatial resolution of OCT b) The research and developments of new imaging techniques for wide clinical applications.
1) Synthesized light source for high spatial resolution of OCT
We proposed the optimization method of the synthesized light source that consists of multi-light sources and showed the decrease of coherence length suppressing the side-lobes.
2) Enhancement of stabilization of heterodyne beat signal
We enhanced the stabilization of heterodyne beat signal using its harmonics. The actual conditions of modulation index were shown by the experiments and simulations for expansions of light sources (laser, superluminescent diode, halogenlamp), phase modulation signals (sinusoidal wave and triangle wave) and harmonics to 8^<th>.
3) The coaxial Mirau interferometer as the compact OCT for wide application
The coaxial Mirau interferometer has been proposed as the compact interferometer. That interferometer consists of can type SLD, collimator lens, half mirror with PZT and objective lens. The axial and lateral spatial resolutions are 21μm, 10μm, respectively. The surface of Japanese coin were measured as the sample of rough surfaces.
4) The imaging method of simultaneous measurements of velocity vector and sectional image
The simultaneous measurements of velocity vector and sectional image have been studied using the Doppler effect by three-beam and the confocal optics. The measured values from -2mm/s to 2mm/s corresponded to calculated ones. The axial and lateral profiles were measured at about 10μm.

Report

(4 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (41 results)

All Other

All Publications (41 results)

  • [Publications] Adrian Dobroiu: "Coaxial Mirau interferometer"Optics Letters. 27. 1153-1155 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Manabu Sato: "Stabilization by harmonic intensities for output signal in heterodyne detection"Applied Optics. 41. 2461-2469 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yan Zhang: "Numerical investigations or optimal synthesis of several low coherence sources for resolution improvement"Optics Communications. 192. 183-192 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 佐藤学: "オプティカル・コヒーレンス・トモグフフィ(OCT)の最新技術"精密工学会・精密工学会誌. 67. 546-549 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yan Zhang: "Resolution improvement in optical coherence tomography by optimally synthesizing light emitting diodes"Optics Letters. 26. 205-207 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 佐藤学: "光コヒーレンストモグフフィによる生体組織の断層画像計測"計測自動制御学会・計測と制御. 39. 259-266 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Adrian Dobroiu: "Coaxial Mirau interferometer"Opt. Lett.. vol.27 no.13. 1153-1155 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Manabu Sato: "Stabilization by harmonic intensities for output signal in heterodyne detection"Appl. Opt.. vol.41, no.13. 2461-2469 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yan Zhang: "Numerical investigations of optimal synthesis of several low coherence sources for resolution improvement"Opt. Commun.. vol.192. 183-192 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yan Zhang: "Resolution improvement in optical coherence tomography by optimally synthesizing light emitting diodes"Opt. Lett.. vol.26, no.4. 205-207 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yan Zhang: "Resolution improvement in optical coherence tomography based on destructive interference"Opt. Commun.. vol.187. 65-70 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yan Zhang: "Characters of the semiconductor laser with strong feedback"Optik. vol.112, no.2. 91-96 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Manabu Sato: "Phase-drift-suppression in heterodyne detection using coherent light source"Opt. Rev.. vol.8, no.1. 37-42 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Adrian Dobroiu: "Coaxial Mirau interferometer for shap measurement of rough surfaces"Proceeding of The 4th International Workshop on Automatic Processing of FringePattern. 391-393 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tomofumi Ikari: "Partially delayed Fizeau interferometer for optical coherence tomography"CLEO/Pacific Rim. TuD1-TuD3 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tomofumi Ikari: "Compact optical coherence tomography system using partially delayed Fizeau interferometer"CLEO' 2001. CTuY, Baltimore. (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kin Pui Chan: "Detection schemes for optical - coherence - domain imaging of biological tissues"Opt. Rev.. vol. 7, no.5. 389-395 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Manabu Sato: "Phase-drift-suppression method using higher order harmonics in heterodyne detection"Opt. Rev.. vol. 7, no.5. 462-467 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Manabu Sato: "Phase-drift-suppression using harmonics in heterodyne detection and its application to optical coherence tomography"Opt. Commun.. vol.184. 95-104 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yan Zhang: "Synthesis of low coherence sources for optical"Optics and optoelectronic inspection and control, SPIE. 4221. (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yan Zhang: "Multiple reference lights low coherence interferometer"Optics and optoelectronic inspection and control, SPIE. 4221. (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Manabu Sato: "Phase-drift-suppression in heterodyne detection and its application to optical coherent tomography"CLEO/Europe-IQEC 2000,. CTuK22, Nice, France. (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Manabu Sato: "Coaxial Michelson interferometer for optical biotomography"Interdisciplinary international conference on polarisation effects in lasers, spe-ctroscopy and optoelectronics (PELS-2000),. 79 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 佐藤学, 丹野直弘: "オプティカル・コヒーレンス・トモグラフィー(OCT)の最新技術"精密工学会誌. Vol.67,no.4. 546-549 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Yan Zhang, Manabu Sato, Naohiro Tanno: "Numerical investigations of optimal synthesis of several low coherence sources or resolution improvement"Opt, Commun.. Vol.192. 183-192 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Manabu Sato, Naohiro Tanno: "Stabilization by harmonic intensities for output signal in heterodyne detection"Appl.Opt.. (Accepted). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Tomofumi Ikari, Manabu Sato, Naohiro Tanno: "Compact optical coherence tomography system using partially delayed Fizeau interferometer"Technical digest of CLEO 2001,(Baltimore, USA). CtuY. 6-11 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Manabu Sato, Masahiro Akiba, Kin Pui Chan, Naohiro Tanno: "New Feasibility of Optical Coherence tomography to Medicine"Technical digest of Joint Symposium on Bio-Sensing and Bio-Imaging, (Yamagata, Japan). 1B-14. 2-4 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Adrian Dobroiu, Hiroshi Sakai, Manabu Sato, Naohiro Tanno: "Coaxial Mirau interferometer for shape measurement of rough surfaces"Proceeding of The 4th International Workshop on Automatic Processing of Fringe Patterns (Fringe2001), (Germany, Sept.). 391-393 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 佐藤学,丹野直弘: "光コヒーレンストモグラフィーによる生体組織の断層画像計測"計測自動制御学会・計測と制御. Vol.39 No.4. 259-266 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 佐藤学,清野勝宏,小野寺一貴,丹野直弘: "ヘテロダインビート信号の高次高調波による位相揺らぎ抑制法と生体断層画像計測への応用"電子情報通信学会論文誌. Vol.J83-C No.6. 533-541 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Manabu Sato,Katsuhiko Seino,Kazutaka Onodera,Naohiro Tanno: "Phase-drift-suppression using harmonics in heterodyne detection and its application to optical coherence tomography"Opt.Commun.. Vol.184. 95-104 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Manabu Sato,Masakazu Endo,Naohiro Tanno: "Phase-drift-suppression method using higher order harmonics in heterodyne detection"Opt.Rev.. Vol.7 No.5. 462-467 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] M.Sato,Y Ikeda,M.Endo,S.fukuda N.Tanno: "Phase-drift-suppression in heterodyne detection using coherent light source"Opt.Rev.. Vol.8 No.1. 37-42 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Yan Zhang,Manabu Sato Naohiro Tanno: "Resolution improvement in optical coherence tomography by optimally synthesizing light emitting diodes"Optics Letters. Vol.26 No.4. 205-207 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] 佐藤学 他: "ヘテロダインビート信号の高次高調波による位相揺らぎ抑制法と生体断層画像計測への応用"電子情報通信学会論文誌. J83-C. (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 佐藤学 他: "光コヒーレンストモグラフィーによる生体組織の断層画像計測"計測自動制御学会・計測と制御. Vol.39,No.4. (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 佐藤学 他: "高次高調波検出による光ヘテロダイン信号処理法と生体断層像計測"電子情報通信学会技術研究報告. Vol.MI99-23 No.191. 19-24 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 遠藤雅和 他: "オプティカルコンフォーカルスキャニングトモグラフィーの基礎特性II"Optics Japan '99 講演予稿集. 23pC2. (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 堀之内光 他: "光ファイバー型マッハツェンダー干渉計におけるハロゲンランプの光学基礎特性"1999年応用物理学会東北支部第54回学術講演会講演予稿集. 9aA10. (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 江畑達也: "ハロゲンランプを用いたフィゾー・マイケルソン干渉系の基礎特性"2000年春季第47回応用物理学関係連合講演会. (2000)

    • Related Report
      1999 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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