| Project/Area Number |
11794033
|
|---|
| Research Category |
Grant-in-Aid for University and Society Collaboration
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | HIROSHIMA UNIVERSITY |
|---|
Principal Investigator |
MASUJIMA Tsutomu Hiroshima University, Faculty of Medicine, Professor, 医学部, 教授 (10136054)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
YAMADA Ryo Japan Medical Supply co. Ltd., Research Center Director, 中央研究所, 所長(研究職)
SHINGAKI Tomoteru Hiroshima University, Faculty of Medicine, Research Associater, 医学部, 教務員 (80314748)
尾島 典行 広島大学, 医学部, 助手 (20311805)
|
|---|
| Project Period (FY) |
1999 – 2001
|
| Project Status |
Completed (Fiscal Year 2001)
|
| Budget Amount *help |
¥7,200,000 (Direct Cost: ¥7,200,000)
Fiscal Year 2001: ¥7,200,000 (Direct Cost: ¥7,200,000)
|
|---|
| Keywords | near IR video-scope / Injector / Injector Needle / Medical Devices / Injector for Next Generation / 近赤外 / 画像解析 |
|---|
| Research Abstract |
1. Analyses of the needle injection into the skin by near IRvideo-scope
Current shape of the injection needles was investigated and the process of injection of the needle into the skin was analyzed by image analysis using near IR video-scope. It was found that the needle top of the injector cut off the skin in flat way and then the tube of the needle go into this space which will make pain.
2. Analysis of silicon oil attachment on to the skin by observation of video-mass scope.
Video-mass scope was developed and it was applied to investigate the attachment of silicon oil onto the skin where the needle was injected. The silicon oil which was coated on the needle of the injector, was transferred onto the injection point of the skin and stayed there even after the taking out.
3. The analysis of injection wound recovery using a time lapse video-scope method
The process of the recovery of injection wound was investigated using model cell layer of confluent 3T3 cells. Time lapse video scope showed that the recovery was accelerated by the presence of inside components of mast cell which was destroyed by the injection of the needle through the skin layer.
4. Laser processing of the needle top using Nd : YAG laser
A Nd : YAG laser was found to be used to make the surface of the needle top to be smooth in order to decrease the pain on insertion of the needle and also used to make the hole in the top.
5. Development of the next generation injector and patent authorization
Based on these results, some types of the next generation injectors were proposed and be applied for patents. 1) the processing of the top sharp which will make less-painful injection, 2) the smoothing of the internal face of the needle top to make less pain, 3) oval shape needle to make less pain, 4) the needle with pain scattering ring or adaptor, 5) small needle with separated blood vacuum correction tube, and these idea were applied for patents.
|
