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Cell Cycle Control

Research Project

Project/Area Number 12060101
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionThe University of Tokyo

Principal Investigator

OKAYAMA Hiroto  東京大学, 大学院医学系研究科, 教授 (40111950)

Co-Investigator(Kenkyū-buntansha) KISHIMOTO Takeo  東京工業大学, 大学院生命理工学研究科, 教授 (00124222)
TSUBATA Takeshi  東京医科歯科大学, 難治疾患研究所, 教授 (80197756)
NISHIDA Yasuyoshi  名古屋大学, 大学院理学研究科, 教授 (50107059)
OHYA Yoshikazu  東京大学, 大学院新領域創成科学研究科, 教授 (20183767)
TOH-E Akio  The University of Tokyo, Department of Biological Sciences, Professor, 大学院理学系研究科, 教授 (90029249)
Project Period (FY) 2000 – 2005
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥346,100,000 (Direct Cost: ¥346,100,000)
Fiscal Year 2006: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2005: ¥30,800,000 (Direct Cost: ¥30,800,000)
Fiscal Year 2004: ¥30,100,000 (Direct Cost: ¥30,100,000)
Fiscal Year 2003: ¥33,100,000 (Direct Cost: ¥33,100,000)
Fiscal Year 2002: ¥77,300,000 (Direct Cost: ¥77,300,000)
Fiscal Year 2001: ¥171,800,000 (Direct Cost: ¥171,800,000)
Keywordscell cycle control / checkpoint control / Sphase onset control / cell death control / cell differentiation control / サイクリン依存性キナーゼ / ユビキチン依存性タンパク分解 / 細胞死と不死化 / 細胞周期と発生・分化 / G1 / G2 / 分化 / アポトーシス / 癌 / アポト-シス / 分裂酵母 / 姉妹染色分体結合 / NRK / 足場非依存性増殖 / Cdc6 / Cdk6
Research Abstract

当特定領域研究は、平成12年度に発足し、「細胞周期制御の分子機構を明らかにすることによって生命科学研究の最重要課題である増殖と分化の制御の分子メカニズムの解明を推進し、21世紀の医学・生物学の諸問題の解決のための知的基盤の形成に資すること」を目的とし研究を推進し、平成18年3月に終了した。
参加者は、計画班員延べ37名、公募班員延べ92名であった。
今年度は、その研究期間の成果の取りまとめを行った。
成果報告書は、1)領域の概要、2)研究領域における研究組織と各研究項目の連携状況、3)交付決定額、4)研究領域の設定目的及びその達成度、5)研究領域内の主な研究成果、6)研究成果の取りまとめ状況、7)班員の意見交換の場である全体進捗会議、8)当該研究分野及び関連研究分野への貢献度、9)研究成果公表状況、10)発表論文リスト、11)主な論文、12)参考資料I(毎年開催し国外から5-12名の招待講演及びほぼ同数の国内招待講演による国際ワークショップー覧)、13)参考資料II(研究課題一覧)からなり、1700頁を超える。
なお、研究成果に関しては、単なる論文発表された成果のみならず、未発表や現在も研究が進行中であるが、細胞周期制御機構の包括的解明のために極めて重要な突破口となりうる新知見をできるだけ記載するように努めた。また主な論文に関しては、トップクラスの国際誌掲載論文のみならず、先進性並びに波及効果の期待される成果の論文も載せるようにした。

Report

(8 results)
  • 2006 Annual Research Report
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • Research Products

    (324 results)

All 2006 2005 2004 2003 2002 2001 2000 Other

All Journal Article (219 results) Book (3 results) Publications (102 results)

  • [Journal Article] Nonviral gene delivery by tetraamino fullerene.2006

    • Author(s)
      Isobe, H., Nakanishi, W., Tomita, N., Jinno, S., Okayama, H., Nakamura, E.
    • Journal Title

      Mol. Pham. 3

      Pages: 124-134

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase.2006

    • Author(s)
      Nishiyama A, Muraki K, Saito M, Ohsumi K, Kishimoto T, Ishikawa F.
    • Journal Title

      EMBO J. 25

      Pages: 575-584

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p90Rsk is required for G1 phase arrest unfertilized starfish eggs.2006

    • Author(s)
      Mori, M., Hara, M., Tachibana, K., Kishimoto, T.
    • Journal Title

      Development 133

      Pages: 1823-1830

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identifying novel subustrates for mouse CDK5 using the yeast Saccharomyces cerevisiae.2006

    • Author(s)
      Horiuchi, Y., Asada, A., Hisanaga, S., Toh-e, Nishizawa, M.
    • Journal Title

      Genes Cells 11

      Pages: 1393-1404

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The tumor suppressor p53 is not required for antigen receptor-mediated apoptosis of B lymphocytes.2006

    • Author(s)
      Devi, S.S., Hagiyama, H., Adachi, T., Miyasaka, N., Tsubata, T.
    • Journal Title

      Signal Transduction 6

      Pages: 54-61

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Bispecific antibodies against modified protein and DNA with oxidized lipids.2006

    • Author(s)
      Akagawa M, Ito S, Toyoda K, Ishi Y, Tatsuda E, Shibata T, Kawai, Y., Ishino K, Kishi Y, Adachi T, Tsubata T, Takasaki Y, Hattori N, Matsuda T, Uchida K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 103

      Pages: 6160-6165

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mi-2 chromatin remodeling factor functions in sensory organ development through proneural gene repression in Drosophila.2006

    • Author(s)
      Yamasaki, Y., Nishida, Y.
    • Journal Title

      Develop. Growth Differ. 48

      Pages: 411-418

    • NAID

      10020141408

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Evaluation of image processing programs for accurate measurement of budding and fission yeast morphology.2006

    • Author(s)
      Suzuki, G., et al.
    • Journal Title

      Curr. Genet. 49

      Pages: 237-247

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nonviral gene delivery by tetraamino fullerene.2006

    • Author(s)
      Isobe, H., Nakanishi, W., Tomita, N., Jinno, S., Okayama, H., Nakamura, E.
    • Journal Title

      Mol. Pharm. 3

      Pages: 124-134

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase.2006

    • Author(s)
      Nishiyama, A., Muraki, K., Saito, M., Ohsumi, K., Kishimoto, T., Ishikawa, F.
    • Journal Title

      EMBO J. 25

      Pages: 575-584

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] p90Rsk is required for Gl phase arrest in unfertilized starfish eggs.2006

    • Author(s)
      Mori, M., Hara, M., Tachibana, K., Kishimoto, T.
    • Journal Title

      Development 133

      Pages: 1823-1830

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identifying novel substrates for mouse CDK5 using the yeast Saccharomyces cerevisiae.2006

    • Author(s)
      Horiuchi, Y., Asada, A., Hisanaga, S., Toh-e, A., Nishizawa, M.
    • Journal Title

      Genes Cells 11

      Pages: 1393-1404

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Bispecific antibodies against modified protein and DNA with oxidized lipids.2006

    • Author(s)
      Akagawa M, Ito S, Toyoda K, Ishii Y, Tatsuda E, Shibata T, Kawai, Y., Ishino K, Kishi Y, Adachi T, Tsubata T, Takasaki Y, Hattori N, Matsuda T, Uchida K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 103

      Pages: 6160-6165

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Evaluation of image processing programs for accurate measurement of budding and fission yeast morphology.2006

    • Author(s)
      Suzuki, G. et al.
    • Journal Title

      Curr Genet. 49

      Pages: 237-247

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The tumor suppressor p53 is not required for antigen receptor-mediated apoptosis of B lymphocytes.2006

    • Author(s)
      Devi, S.S., Hagiyama, H., Adachi, T., Miyasaka, N., Tsubata, T.
    • Journal Title

      Signal Transduction (印刷中)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Bispecific antibodies against modified protein and DNA with oxidized lipids.2006

    • Author(s)
      Akagawa, M., Ito, S., Toyoda, K., Ishii, Y., Tatsuda, E., Shibata, T., Kawai, Y., Ishino, K., Kishi, Y., Adachi, T., Tsubata, T., Takasaki, Y., Hattori, N., Matsuda, T., Uchida, K.
    • Journal Title

      Proc.Natl.Acad.Sci.USA (印刷中)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Gene delivery by aminofullerene : structural requirements for efficient transfection.2006

    • Author(s)
      Isobe, H., Nakanishi, W., Tomita, N., Jinno S., Okayama, H., Nakamura, E.
    • Journal Title

      Chemistry-An Asian J. (印刷中)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Inhibition of Cdk6 expression through p38 MAP kinase is involved in differentiation of mouse prechondrocyte ATDC5.2005

    • Author(s)
      Moro T, Ogasawara T, Chikuda H, Ikeda T, Ogata N, Maruyama Z, Komori T, Hoshi K, Chung UI, Nakamura K, Okayama H, Kawaguchi H.
    • Journal Title

      J. Cell Physiol. 204

      Pages: 927-933

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] APC/C-Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs.2005

    • Author(s)
      Yamamoto, T.M., Iwabuchi, M., Ohsumi, K., Kishimoto, T.
    • Journal Title

      Dev. Biol. 279

      Pages: 345-355

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs.2005

    • Author(s)
      Shintomi K, Iwabuchi M, Saeki H, Ura K, Kishimoto T, Ohsumi, K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102

      Pages: 8210-8215

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] In memory of Andre Picard : 1950-2004(Obituary).2005

    • Author(s)
      Kishimoto, T.
    • Journal Title

      Biol. Cell 97

      Pages: 349-350

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell cycle unleashed (News and Views).2005

    • Author(s)
      Kishimoto, T.
    • Journal Title

      Nature 437

      Pages: 963-965

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Functional analysis of Rpn6p, a lid component of the 26 S proteasome, using temperature-sensitive rpn6 mutants of the yeast Saccharomyces cerevisiae.2005

    • Author(s)
      Isono, E., Saito, N., Kamata, N., Saeki, Y., Toh-e, A.
    • Journal Title

      J Biol Chem. 280

      Pages: 6537-6547

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] In vivo time-resolved Raman imaging of a spontaneous death process of a single budding yeast cell.2005

    • Author(s)
      Yasuaki Nito, Akio Tho-e, Hiro-o Hamaguchi
    • Journal Title

      J Raman Spectroscopy 36

      Pages: 837-839

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] LAS24/KOG1, a component of the TOR complex 1 (TORC1) is needed for resistance to local anesthetic and normal distribution of actin cytoskeleton in yeast.2005

    • Author(s)
      Tomoyuki Araki, Yukifumi Uesono, Tomoko Oguchi, Akiko Toh-e
    • Journal Title

      Genes Genet Syst. 80

      Pages: 325-343

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity.2005

    • Author(s)
      Saeki, Y., Isonom, E., Toh-e, A.
    • Journal Title

      Method. Enzymol. 399

      Pages: 215-227

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Knocking out ubiquitin proteasome system function in vivo and in vitro with genetically encodable tandem ubiquitin.2005

    • Author(s)
      Saeki, Y., Isonom, E., Shimada, M., Kawahara, H., Yokosawa, H., Toh-e, A.
    • Journal Title

      Method. Enzymol. 399

      Pages: 64-74

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] B cell abnormality and autoimmune disorders.2005

    • Author(s)
      Tsubata, T.
    • Journal Title

      Autoimmunity 38

      Pages: 331-337

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] High-dimensional and large-scale phenotyping of yeast mutants.2005

    • Author(s)
      Ohya, Y., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102

      Pages: 19015-19020

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Piperazine propanol derivative as a novel antifungal targeting 1,3-beta-D-glucan synthase.2005

    • Author(s)
      Kondoh, O., et al.
    • Journal Title

      Biol Pharm Bull. 28

      Pages: 2138-2141

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Data Mining Tools for Saccharomyces Cerevisiae Morphological Database.2005

    • Author(s)
      Saito, T., et al.
    • Journal Title

      Nuc. Acid Res. 33

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular dissection of ARP1 regions required for nuclear migration and cell wall integrity checkpoint functions in Saccharomyces cerevisiae.2005

    • Author(s)
      Igarashi, R., et al.
    • Journal Title

      Cell Struct Funct. 30

      Pages: 57-67

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of actin and polarisome in morphological change during spore germination of Saccharomyces cerevisiae.2005

    • Author(s)
      Kono, K., et al.
    • Journal Title

      Yeast 22

      Pages: 129-139

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs : Implications for the molecular pathogenesis of human mitochondrial diseases.2005

    • Author(s)
      Umeda, N., et al.
    • Journal Title

      J Biol Chem. 280

      Pages: 1613-1624

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs.2005

    • Author(s)
      Shintomi, K., Iwabuchi, M., Saeki, H., Ura, K., Kishimoto, T., Ohsumi, K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102

      Pages: 8210-8215

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] In memory of Andre Picard : 1950-2004 (Obituary).2005

    • Author(s)
      Kishimoto, T.
    • Journal Title

      Biol. Cell 97

      Pages: 349-350

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] In vivo time-resolved Raman imaging of a spontaneous death process of a single budding yeast cell.2005

    • Author(s)
      Yasuaki Naito, Akio Toh-e, Hiro-o Hamaguchi
    • Journal Title

      J Raman Spectroscopy 36

      Pages: 837-839

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] LAS24/KOG1, a component of the TOR complex 1 (TORC1) is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast.2005

    • Author(s)
      Tomoyuki Araki, Yukifumi Uesono, Tomoko Oguchi, Akio Toh-e
    • Journal Title

      Genes Genet Syst. 80

      Pages: 325-343

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity.2005

    • Author(s)
      Saeki, Y., Isono, E., Toh-e, A.
    • Journal Title

      Method. Enzymol. 399

      Pages: 215-227

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Knocking out ubiquitin proteasome system function in vivo and in vitro with genetically encodable tandem ubiquitin.2005

    • Author(s)
      Saeki, Y., Isono, E., Shimada, M., Kawahara, H., Yokosawa, H., Toh-e, A.
    • Journal Title

      Method. Enzymol. 399

      Pages: 64-74

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] High-dimensional and large-scale phenotyping of yeast mutants.2005

    • Author(s)
      Ohya, Y. et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102

      Pages: 19015-19020

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Piperazine propanol derivative as a novel antifungal targeting 1,3-beta-D-glucan synthase.2005

    • Author(s)
      Kondoh, O. et al.
    • Journal Title

      Biol Pharm Bull. 28

      Pages: 2138-2141

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Data Mining Tools for Saccharomyces Cerevisiae Morphological Database.2005

    • Author(s)
      Saito, T. et al.
    • Journal Title

      Nuc.Acid Res. 33

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular dissection of ARP1 regions required for nuclear migration and cell wall integrity checkpoint functions in Saccharomyces cerevisiae.2005

    • Author(s)
      Igarashi, R. et al.
    • Journal Title

      Cell Struct Funct. 30

      Pages: 57-67

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of actin and polarisome in morphological change during spore germination of Saccharomyces cerevisiae.2005

    • Author(s)
      Kono, K. et al.
    • Journal Title

      Yeast 22

      Pages: 129-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs: Implications for the molecular pathogenesis of human mitochondrial diseases.2005

    • Author(s)
      Umeda, N. et al.
    • Journal Title

      J Biol Chem. 280

      Pages: 1613-1624

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibition of Cdk6 expression through p38 MAP kinase is involved in differentiation of mouse prechondrocyte ATDC5.2005

    • Author(s)
      Moro, T., Ogasawara, T., Chikuda, H., Ikeda, T., Ogata, N., Maruyama, Z., Komori, T., Hoshi, K., Chung, U.I., Nakamura, K., Okayama.H., Kawaguchi H.
    • Journal Title

      J.Cell Physiol. 204

      Pages: 927-933

    • Related Report
      2005 Annual Research Report
  • [Journal Article] APC/C-Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs.2005

    • Author(s)
      Yamamoto, T.M., Iwabuchi, M., Ohsumi, K., Kishimoto, T.
    • Journal Title

      Dev.Biol. 279

      Pages: 345-355

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs.2005

    • Author(s)
      Shintomi, K., Iwabuchi, M., Saeki, H., Ura, K., Kishimoto, T., Ohsumi, K.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102

      Pages: 8210-8215

    • Related Report
      2005 Annual Research Report
  • [Journal Article] in vivo time-resolved Raman imaging of a spontaneous death process of a single budding yeast cell.2005

    • Author(s)
      Yasuaki Naito, Akio Toh-e, Hiro-o Hamaguchi
    • Journal Title

      J Raman Spectroscopy 36

      Pages: 837-839

    • Related Report
      2005 Annual Research Report
  • [Journal Article] LAS24/KOG1, a component of the TOR complex 1 (TORC1) is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast.2005

    • Author(s)
      Tomoyuki Araki, Yukifumi Uesono, Tomoko Oguchi, Akio Toh-e
    • Journal Title

      Genes Genet Syst. 80・5

      Pages: 325-343

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6(Cdk6).2004

    • Author(s)
      Ogasawara, T., Katagiri, M., Yamamoto, A., Hoshi, K., Takato, T., Nakamura, K., Tanaka, S., Okayama, H., Kawaguchi, H.
    • Journal Title

      J. Bone Miner. Res. 19

      Pages: 1128-1136

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Bone morphogenetic protein-2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6.2004

    • Author(s)
      Ogasawara, T., Kawaguchi, H., Jinno, S., Hoshi, K., Itaka, K., Takato, T., Nakamura, K., Okayama, H.
    • Journal Title

      Mol. Cell. Biol. 24

      Pages: 6560-6568

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Emil-mediated M-phase arrest in Xenopus eggs is distinct from cytostatic factor arrest.2004

    • Author(s)
      Ohsumi, K., Koyanagi, A., Yamamoto, T.M., Gotoh, T., Kishimoto, T.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 101

      Pages: 12531-12536

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] PDK1 is required for the hormonal signalling pathway leading to meiotic resumption in starfish oocytes.2004

    • Author(s)
      Hiraoka, D., Hori-Oshima, S., Fukuhara, T., Tachibana, K, Okumura, E., Kishimoto, T.
    • Journal Title

      Dev. Biol. 276

      Pages: 330-336

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Morphological and biochemical changes of neurofilaments in aged rat sciatic nerve axons.2004

    • Author(s)
      Uchida A, Tashiro T, Komiya Y, Yorifuji H, Kishimoto T, Hisanaga S.
    • Journal Title

      J. Neurochem. 88

      Pages: 735-745

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] More than G1 or G2 arrest : Useful starfish oocyte system for investigating skillful MAP kinase.2004

    • Author(s)
      Kishimoto, T.
    • Journal Title

      Biol. Cell 96

      Pages: 241-244

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Simultaneous yet independent regulation of actin cytoskeleton organization and translation initiation by glucose in Saccharomyces cerevisiae.2004

    • Author(s)
      Uesono, Y, Ashe, P., Toh-e, A.
    • Journal Title

      Mol. Biol. Cell 15

      Pages: 1544-1556

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ybr267W is new cytoplasmic protein belonging to the mitotic signaling network of Saccharomyces cerevisiae.2004

    • Author(s)
      Iwase, M., Toh-e, A.
    • Journal Title

      Cell Struc. Funct. 29

      Pages: 1-15

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Yeast Pho85 kinase is required for proper gene expression during the diauxoc shift.2004

    • Author(s)
      Nishizawa, M., Katou, H., Shirahige, K, Toh-e, A.
    • Journal Title

      Yeast 21

      Pages: 903-918

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rpn7 is required for the structural integrity of the 26S proteasome of Saccharomyces Cerevisiae2004

    • Author(s)
      Isono, E., et al.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 27168-27176

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sem1p is a novel subunit of the 26S proteasome from Saccharomyces cerevisiae.2004

    • Author(s)
      Sone, T., et al.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 28807-28816

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Intracellularly inducible, ubiquintin hydrolase-insensitive tandem ubiquitins inhibit 26S proteasome activity and cell division.2004

    • Author(s)
      Saeki, Y., et al.
    • Journal Title

      Genes Genet. Syst. 79

      Pages: 77-86

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage2004

    • Author(s)
      Saeki, Y., et al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 320

      Pages: 840-845

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in budding yeast.2004

    • Author(s)
      Itoh, T., Toh-e, A., Matsui, Y.
    • Journal Title

      EMBO J. 23

      Pages: 2520-2530

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Forchlorfenuron, a phenylurea cytokinin, disturbs septin organization in Saccharomyces cerevisiae.2004

    • Author(s)
      Iwase, M., Okada, S., Oguchi, T., Toh-e, A.
    • Journal Title

      Genes Genet Syst. 79

      Pages: 199-206

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ectopic CD40 ligand expression on B cells trigger intestinal inflammation.2004

    • Author(s)
      Kawamura T, Knanai T, Dohi T, Uraushihara K, Totsuka T, Iiyama R, Taneda C, Yamazaki M, Nakamura T, Higuchi T, Aiba Y, Tsubata T, Watanabe M.
    • Journal Title

      J. Immunol. 172

      Pages: 6388-6397

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular interactions regulate BCR signal inhibition by CD22 and CD72.2004

    • Author(s)
      Nitschke, L., Tsubata, T.
    • Journal Title

      Trends Immunol. 25

      Pages: 543-550

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Armadillo/Pangolin regulates PCNA and DREF promoter activities.2004

    • Author(s)
      Kwon, E., et al.
    • Journal Title

      Biochim. Biophys. Acta. 1679

      Pages: 256-262

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dynactin complex is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae.2004

    • Author(s)
      Suzuki, M., et al.
    • Journal Title

      Nat. Cell Biol. 6

      Pages: 861-871

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel mechanism of intragenic complementation between Phe to Ala calmodulin mutations.2004

    • Author(s)
      Okano, H., Ohya, Y.
    • Journal Title

      J. Biochem. 135

      Pages: 289-295

    • NAID

      10016198578

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell shape and growth of budding yeast cells in restrictive microenvironments.2004

    • Author(s)
      Suzuki, M., et al.
    • Journal Title

      Yeast 21

      Pages: 983-989

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular mechanism of vde-initiated intein homing in yeast nuclear genome.2004

    • Author(s)
      Fukuda, T., et al.
    • Journal Title

      Adv Biophys. 38

      Pages: 215-232

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] SCMD : Saccaromyces cerevisiae morphological database.2004

    • Author(s)
      Saito, T.L., et al.
    • Journal Title

      Nuc. Acid Res. 32

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Analysis of the molecular interaction of the farnesyl moiety of transducin through use of a photoreactive farnesyl analog.2004

    • Author(s)
      Hagiwara, K., et al.
    • Journal Title

      Biochemstry 43

      Pages: 300-309

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Development of Image Processing program for Yeast Cell Morphology.2004

    • Author(s)
      Ohtani, M., et al.
    • Journal Title

      J. Bioinfo. Comput. Biol. 1

      Pages: 695-709

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).2004

    • Author(s)
      Ogasawara, T., Katagiri, M., Yamamoto, A., Hoshi, K., Takato, T., Nakamura, K., Tanaka, S., Okayama, H., Kawaguchi, H.
    • Journal Title

      J. Bone Miner. Res. 19

      Pages: 1128-1136

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] More than Gl or G2 arrest : Useful starfish oocyte system for investigating skillful MAP kinase.2004

    • Author(s)
      Kishimoto, T.
    • Journal Title

      Biol. Cell 96

      Pages: 241-244

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Simultaneous yet independent regulation of actin cytoskeleton organization and translation initiation by glucose in Saccharomyces cerevisiae.2004

    • Author(s)
      Uesono, Y., Ashe, P., Toh-e, A.
    • Journal Title

      Mol. Biol. Cell 15

      Pages: 1544-1556

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Yeast Pho85 kinase is required for proper gene expression during the diauxic shift.2004

    • Author(s)
      Nishizawa, M., Katou, H., Shirahige, K., Toh-e, A.
    • Journal Title

      Yeast 21

      Pages: 903-918

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rpn7 is required for the structural integrity of the 26S proteasome of Saccharomyces cerevisiae.2004

    • Author(s)
      Isono, E., et al.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 27168-27176

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Semlp is a novel subunit of the 26S proteasome from Saccharomyces cerevisiae.2004

    • Author(s)
      Sone, T., et al.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 28807-28816

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Intracellularly inducible, ubiquitin hydrolase-insensitive tandem ubiquitins inhibit the 26S proteasome activity and cell division.2004

    • Author(s)
      Saeki, Y., et al.
    • Journal Title

      Genes Genet. Syst. 79

      Pages: 77-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage.2004

    • Author(s)
      Saeki, Y., et al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 320

      Pages: 840-845

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mmrlp is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast.2004

    • Author(s)
      Itoh, T., Toh-e, A., Matsui, Y.
    • Journal Title

      EMBO J. 23

      Pages: 2520-2530

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ectopic CD40 ligand expression on B cells trigger intestinal inflammation.2004

    • Author(s)
      Kawamura T, Kanai T, Dohi T, Uraushihara K, Totsuka T, Iiyama R, Taneda C, Yamazaki M, Nakamura T, Higuchi T, Aiba Y, Tsubata T, Watanabe M.
    • Journal Title

      J. Immunol. 172

      Pages: 6388-6397

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dynactin complex is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae.2004

    • Author(s)
      Suzuki, M. et al.
    • Journal Title

      Nat. Cell Biol. 6

      Pages: 861-871

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell shape and growth of budding yeast cells in restrictive microenvironments.2004

    • Author(s)
      Suzuki, M. et al.
    • Journal Title

      Yeast 21

      Pages: 983-989

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular mechanism of vde-initiated intein homing in yeast nuclear genome.2004

    • Author(s)
      Fukuda T, et al.
    • Journal Title

      Adv Biophys. 38

      Pages: 215-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] SCMD:Saccaromyces cerevisiae morphological database.2004

    • Author(s)
      Saito, T.L.et al.
    • Journal Title

      Nuc. Acid Res. 32

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Analysis of the molecular interaction of the farnesyl moiety of transducin through use of a photoreactive farnesyl analog.2004

    • Author(s)
      Hagiwara, K. et al.
    • Journal Title

      Biochemstry 43

      Pages: 300-309

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Development of Image Processing Program for Yeast Cell Morphology.2004

    • Author(s)
      Ohtani, M. et al.
    • Journal Title

      J. Bioinfo. Comput. Biol. 1

      Pages: 695-709

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Bone morphogenetic protein-2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk62004

    • Author(s)
      Ogasawara, T., Kawaguchi, H., Jinno, S., Hoshi, K., Itaka, K., Takato, T., Nakamura, K., Okayama, H.
    • Journal Title

      Mol.Cell.Biol. 24

      Pages: 6560-6568

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Emil-mediated M-phase arrest in Xenopus eggs is distinct from cytostatic factor arrest.2004

    • Author(s)
      Ohsumi, K., Koyanagi, A., Yamamoto, T.M., Gotoh, T., Kishimoto, T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 12531-12536

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Involvement of cell cycle progression in survival signaling through CD40 in B lymphocyte2004

    • Author(s)
      Hirai, H., Adachi, T., Tsubata, T.
    • Journal Title

      Cell Death Differ. 11

      Pages: 261-269

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Rpn7 is required for the structural integrity of the 26S proteasome of Saccharomyces2004

    • Author(s)
      Isono, E., Saeki, Y., Yokosawa, H., Toh-e, A.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 27168-27176

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Armadillo/Panglion regulates PCNA and DREF promoter activities.2004

    • Author(s)
      Kwon, E., Hayashi, Y., Otsuki, K., Hirose, F., Nishida, Y., Yoo, M.-A., Yamaguchi, M.
    • Journal Title

      Biochem.Biophys.Acta 1679

      Pages: 256-262

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Dynactin complex is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae2004

    • Author(s)
      Suzuki, M., Igarashi, R., Sekiya, M., Utsugi, T., Morishita, S., Yukawa, M., Ohya, Y.
    • Journal Title

      Nat.Cell Biol. 6

      Pages: 861-871

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Overexpression of Cdk6-cyclin D3 highly sensitizes cells to physical and chemical transformation.2003

    • Author(s)
      Chen, Q., Lin, J., Jinno, S., Okayama, H.
    • Journal Title

      Oncogene 22

      Pages: 992-1001

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Distinct regulators for Plk1 activation in starfish meiotic and early embryonic cycles.2003

    • Author(s)
      Okano-Uchida, T., Okumura, E., Iwashita, M, Yoshida, H., Tachibana, K., Kishimoto, T.
    • Journal Title

      EMBO J. 22

      Pages: 5633-5642

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Localization and dynamics of Cdc2-cyclin B during meiotic reinitiation in starfish oocytes.2003

    • Author(s)
      Terasaki, M., Okumura, E., Hinkel, B., Kishimoto, T.
    • Journal Title

      Mol. Biol. Cell 14

      Pages: 4685-4694

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation.2003

    • Author(s)
      Saito T, Onuki R, Fujita Y, Kusakawa G, Ishiguro K, Bibb JA, Kishimoto T, Hisanaga S.
    • Journal Title

      J. Neurosci. 23

      Pages: 1189-1197

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein.2003

    • Author(s)
      Honma N, Asada A, Takeshita S, Enomoto M, Yamakawa E, Tsutsumi K, Saito T, Satoh T, Itoh H, Kaziro Y, Kishimoto T, Hisanaga S.
    • Journal Title

      Biochem. Biophys. Res. Comm. 310

      Pages: 398-404

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell cycle control during meiotic maturation.2003

    • Author(s)
      Kishimoto, T.
    • Journal Title

      Curr. Opin. Cell Biol. 15

      Pages: 654-663

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ras recruits mitotic exit regulator Lte1 to the bud cortex in budding yeast.2003

    • Author(s)
      Yoshida, S., Ichihashi, R., Toh-e, A.
    • Journal Title

      J. Cell. Biol. 161

      Pages: 889-897

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Comparative analysis of yeast PIAS-type SUMO ligases in vitro and in vivo.2003

    • Author(s)
      Takahashi, Y., Toh-e, A., Kikuchi, Y.
    • Journal Title

      J. Biochem. 133

      Pages: 415-422

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rsp5-Bul1/2 complex is necessary for the HSE-mediated gene expression in budding yeast.2003

    • Author(s)
      Kaida, D., Toh-e, A., Kikuchi, Y.
    • Journal Title

      Biochem. Biophys. Res. Commun. 306

      Pages: 1037-1041

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Phosphorelay-regulated degradation of the yeast Ssklp response regulator by the ubiquitin-proteasome system.2003

    • Author(s)
      Sato, N., Kawahara, H., Toh-e, A., Maeda, T.
    • Journal Title

      Mol. Cell. Biol. 23

      Pages: 6662-6671

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.2003

    • Author(s)
      Suzuki, A., Kaisyo, T., Ohishi, M., Tsukio-Yamaguschi, M., Tsubata, T., Koni, P.A., Sasaki, T., Mak, T.W., Nakano, T.
    • Journal Title

      J. Exp. Med 197

      Pages: 657-667

    • NAID

      120004837363

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibitory co-receptors activated by antigens but not by aniti immunoglobulinheavy chain antibodies install requirement of co-stimulation through CD40 for survival and proliferation of B cells.2003

    • Author(s)
      Hokazono, Y., Adachi, T., Wabl, M., Tada, N., Amagasa, T., Tsubata T.
    • Journal Title

      J. Immunol. 171

      Pages: 261-269

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of cell cycle progression in survaival signaling through CD40 inB lymphocyte line Wehi-231.2003

    • Author(s)
      Hirai H, Adachi T, Tsubata T.
    • Journal Title

      Cell. Death. Differ 11

      Pages: 261-269

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster and virilis.2003

    • Author(s)
      Kwon, E., et al.
    • Journal Title

      Gene 309

      Pages: 101-116

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila.2003

    • Author(s)
      Furukawa, K., et al.
    • Journal Title

      J. Cell Sci. 116

      Pages: 3811-3823

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Distinct regulators for Plkl activation in starfish meiotic and early embryonic cycles.2003

    • Author(s)
      Okano-Uchida, T., Okumura, E., Iwashita, M., Yoshida, H., Tachibana, K., Kishimoto, T.
    • Journal Title

      EMBOJ. 22

      Pages: 5633-5642

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ras recruits mitotic exit regulator Ltel to the bud cortex in budding yeast.2003

    • Author(s)
      Yoshida, S., Ichihashi, R., Toh-e, A.
    • Journal Title

      J. Cell Biol. 161

      Pages: 889-897

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rsp5-Bull/2 complex is necessary for the HSE-mediated gene expression in budding yeast.2003

    • Author(s)
      Kaida, D., Toh-e, A., Kikuchi, Y.
    • Journal Title

      Biochem. Biophys. Res. Commun. 306

      Pages: 1037-1041

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.2003

    • Author(s)
      Suzuki, A., Kaisho, T., Ohishi, M., Tsukio-Yamaguchi, M., Tsubata, T., Koni, P.A., Sasaki, T., Mak, T.W., Nakano, T.
    • Journal Title

      J. Exp. Med 197

      Pages: 657-667

    • NAID

      120004837363

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibitory co-receptors activated by antigens but not by antigen immunoglobulinheavy chain antibodies install requirement of co-stimulation through CD40 for survival and proliferation of B cells.2003

    • Author(s)
      Hokazono, Y., Adachi, T., Wabl, M., Tada, N., Amagasa, T., Tsubata, T.
    • Journal Title

      J. Immunol. 171

      Pages: 1835-1843

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of cell cycle progression in survaival signaling through CD40 inB lymphocyte line WEHI-231.2003

    • Author(s)
      Hirai, H., Adachi, T., Tsubata, T.
    • Journal Title

      Cell. Death. Differ. 11

      Pages: 261-269

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster and virilis.2003

    • Author(s)
      Kwon, E. et al.
    • Journal Title

      Gene 309

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila.2003

    • Author(s)
      Furukawa, K. et al.
    • Journal Title

      J. Cell Sci. 116

      Pages: 3811-3823

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cdc6 requires anchorage for its expression.2002

    • Author(s)
      Jinno, S., Yageta, M., Nagata, A., Okayama, H.
    • Journal Title

      Oncogene 21

      Pages: 1777-1784

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation.2002

    • Author(s)
      Hiroi, N., Ito, T., Yamamoto, H., Ochiya, T., Jinno, S., Okayama, H.
    • Journal Title

      EMBO J. 21

      Pages: 5235-5244

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Akt inhibits Mytl in the signalling pathway that leads to meiotic G2/M-phase transition.2002

    • Author(s)
      Okumura, E., Fukuhara, T., Yoshida, H., Hanada, S., Kozutsumi, R, Mori, M., Tachibana, K., Kishimotom, T.
    • Journal Title

      Nature Cell Biol. 4

      Pages: 111-116

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Coordinated regulation of M phase exit and S phase entry by the Cdc2 activity level in the early embryonic cell cycle.2002

    • Author(s)
      Iwabuchi, M., Ohsumi, K., Yamamoto, T.M., Kishimoto, T.
    • Journal Title

      Dev. Biol. 243

      Pages: 34-43

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Transient inhibition of translation initiation by osmotic stress.2002

    • Author(s)
      Uesono, Y., Toh-e, A.
    • Journal Title

      J. Biol. Chem. 277

      Pages: 13848-13855

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Normal assembly of 60S ribosomal subunits is required for the signaling in response to a secretory defect in Saccharomyces cerevisaie.2002

    • Author(s)
      Miyoshi, K., Tsujii, R., Yoshida, H., Maki, Y., Wada, A., Matsui, Y., Toh-e, A., Mizuta, K.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 18334-18339

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression.2002

    • Author(s)
      Kaida, D., Yashiroda, H., Toh-e, A., Kikuchi, Y.
    • Journal Title

      Genes Cells 7

      Pages: 543-552

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rpf2p, and evolutionally conserved protein, interacts with ribosomal protein L11 and is essential for processing of 27SB pre-rRNA to 25SrRNA and 60S ribosomal subunit assembly in Saccharomyces cerevisiae.2002

    • Author(s)
      Morita, D., Miyshi, K., Matsui, Y., Tho-e, A., Shinkawa, H., Miyakawa, T., Mizuta, K.
    • Journal Title

      J. Biol. Chem. 277

      Pages: 28780-28786

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiae.2002

    • Author(s)
      Yoshida, S., Asakawa, K., Toh-e, A.
    • Journal Title

      Curr Biol. 12

      Pages: 944-950

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Budding yeast Cdc5 phosphorylates Net1 and assists Cdc14 release from the nucleolus.2002

    • Author(s)
      Yoshida, S., Toh-e, A.
    • Journal Title

      Biochem. Biophys. Res. Commun. 294

      Pages: 687-691

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A defect in KLAP104 alleviates the requirement of the MEN (mitotic exit network) gene function in Saccharomyces cerevisiae.2002

    • Author(s)
      Asakawa, K., Toh-e, A.
    • Journal Title

      Genetics 162

      Pages: 1545-1556

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of ubiquitin-like proteins binding subunits of the 26S proteasome.2002

    • Author(s)
      Saeki, Y., Sone, T., Toh-e, A., Yokosawa, H.
    • Journal Title

      Biochem. Biophys. Res. Commun. 296

      Pages: 813-819

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae.2002

    • Author(s)
      Tone, Y., Toh-e, A.
    • Journal Title

      Genes Dev. 16

      Pages: 3142-3157

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Complex formation with the class V myosin is essential for Ypt11p, a rab type small GTPase, to facilitate the Myo2p function for mitochondrial distribution in the budding yeast.2002

    • Author(s)
      Itoh, T., Watabe, A., Toh-e, A., Matsui, Y.
    • Journal Title

      Mol. Cell. Biol. 22

      Pages: 7744-7757

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic characterization of genes encoding enzymes catalyzing addition of phosphoethanolamine to the glycosylphosphatidylinositol anchor in Saccharomyces cerevisiae.2002

    • Author(s)
      Toh-e, A., Oguchi, T.
    • Journal Title

      Gene. Genet. Syst. 77

      Pages: 309-322

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The small GTPase Rho3 and diaphanous/forming For3 function in polarized cell growth in fission yeast.2002

    • Author(s)
      Nakano, K, Imai, J., Arai, R., Toh-e, A., Matsui, Y., Mabuchi, I.
    • Journal Title

      J. Cell. Sci. 115

      Pages: 4629-4639

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cutting Edge : Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease.2002

    • Author(s)
      Higuchi T, Aiba Y, Nomura T, Matsuda J, Mocida K, Suzuki M, kikutani H, Honjo T, Nisioka K, Tsubata T.
    • Journal Title

      J. Immunol. 168

      Pages: 9-12

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A distinct signaling pathway used by the IgG-containing B cell an tigen receptor.2002

    • Author(s)
      Wakabayashi, C., Adachi, T., Wienands, J., Tsubata, T.
    • Journal Title

      Science. 298

      Pages: 2392-2395

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Drosophila myosin phosphatase and its role in dorsal closure.2002

    • Author(s)
      Mizuno, T., Tsutsui, K., Nishida, Y
    • Journal Title

      Development 129

      Pages: 1215-1223

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of the dCaMKII-GAL4 driver line Whose expression is controlled by the Drosophila Ca2+/calmodulin- Dependent protein kinase II promoter.2002

    • Author(s)
      Takamatsu, Y., et al.
    • Journal Title

      Cell Tissue Res. 310

      Pages: 237-252

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mammalian Rcdl is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation.2002

    • Author(s)
      Hiroi, N., Ito, T., Yamamoto, H., Ochiya, T., Jinno, S., Okayama, H.
    • Journal Title

      EMBO J. 21

      Pages: 5235-5244

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Akt inhibits Mytl in the signalling pathway that leads to meiotic G2/M-phase transition.2002

    • Author(s)
      Okumura, E., Fukuhara, T., Yoshida, H., Hanada, S., Kozutsumi, R., Mori, M., Tachibana, K., Kishimoto, T.
    • Journal Title

      Nature Cell Biol. 4

      Pages: 111-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Normal assembly of 60S ribosomal subunits is required for the signaling in response to a secretory defect in Saccharomyces cerevisiae.2002

    • Author(s)
      Miyoshi, K., Tsujii, R., Yoshida, H., Maki, Y., Wada, A., Matsui, Y., Toh-e, A., Mizuta, K.
    • Journal Title

      J. Biol.Chem. 277

      Pages: 18334-18339

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Yeast Whi2 and Psrl-phosphatase form a complex and regulate STRE-mediated gene expression.2002

    • Author(s)
      Kaida, D., Yashiroda, H., Toh-e, A., Kikuchi, Y.
    • Journal Title

      Genes Cells 7

      Pages: 543-552

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rpf2p, and evolutionally conserved protein, interacts with ribosomal protein L11 and is essential for processing of 27SB pre-rRNA to 25S rRNA and 60S ribosomal subunit assembly in Saccharomyces cerevisiae.2002

    • Author(s)
      Morita, D., Miyshi, K., Matsui, Y., Toh-e, A., Shinkawa, H., Miyakawa, T., Mizuta, K.
    • Journal Title

      J. Biol. Chem. 277

      Pages: 28780-28786

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Budding yeast Cdc5 phosphorylates Netl and assists Cdc14 release from the nucleolus.2002

    • Author(s)
      Yoshida, S., Toh-e, A.
    • Journal Title

      Biochem. Biophys. Res. Commun 294

      Pages: 687-691

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of ubiquitin-like proteins binding subunits of the 26S proteasome.2002

    • Author(s)
      Saeki, Y., Sone, T., Toh-e, A., Yokosawa, H.
    • Journal Title

      Biochem. Biophys. Res. Commun. 286

      Pages: 813-819

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Complex formation with the class V myosin is essential for Yptllp, a rab type small GTPase, to facilitate the Myo2p function for mitochondrial distribution in the budding yeast.2002

    • Author(s)
      Itoh, T., Watabe, A., Toh-e, A., Matsui, Y.
    • Journal Title

      Mol. Cell. Biol. 22

      Pages: 7744-7757

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The small GTPase Rho3 and diaphanous/forming For3 function in polarized cell growth in fission yeast.2002

    • Author(s)
      Nakano, K., Imai, J., Arai, R., Toh-e, A., Matsui, Y, Mabuchi, I.
    • Journal Title

      J. Cell Sci. 115

      Pages: 4629-4639

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cutting Edge : Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease.2002

    • Author(s)
      Higuchi T, Aiba Y, Nomura T, Matsuda J, Mochida K, Suzuki M, Kikutani H, Honjo T, Nishioka K, Tsubata T.
    • Journal Title

      J. Immunol. 168

      Pages: 9-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A distinct signaling pathway used by the IgG-containing B cell antigen receptor.2002

    • Author(s)
      Wakabayashi, C., Adachi, T., Wienands, J., Tsubata, T.
    • Journal Title

      Science 298

      Pages: 2392-2395

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Drosophila myosin phosphatase and its role in dorsal closure.2002

    • Author(s)
      Mizuno, T., Tsutsui, K, Nishida, Y
    • Journal Title

      Development 129

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of the dCaMKII-GAL4 driver line Whose expression is controlled by the Drosophila Ca2+/calmodulin-Dependent protein kinase II promoter.2002

    • Author(s)
      Takamatsu, Y., et al.
    • Journal Title

      Cell Tissue Res. 310

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Oncogenic cell cycle start control.2001

    • Author(s)
      Jinno, S., Lin, J., Yageta, M., Okayama, H.
    • Journal Title

      Mutatin Reseach. 477

      Pages: 23-29

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence.2001

    • Author(s)
      Lin, J., Jinnno, S., Okayama, H.
    • Journal Title

      Oncogene 20

      Pages: 2000-2009

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.2001

    • Author(s)
      Tanaka, K., Hao, Z., Kai, M., Okayama, H.
    • Journal Title

      EMBO J. 20

      Pages: 5779-5790

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Anticancer agent E7070 inhibits amino acid and uracil transport in fission yeast.2001

    • Author(s)
      Tsukahara K, Watanabe T, Hata-Sugi N, Yoshimatsu K, Okayama H, Nagasu T.
    • Journal Title

      Mol Pharmacol. 60

      Pages: 1254-1259

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synthesis and Transfection Capability of Multi-Functionalized Fullerene Polyamine.2001

    • Author(s)
      Isobe H, Tomita N, Jinno S, Okayama H, Nakamura E.
    • Journal Title

      Chemistry Letters. 30

      Pages: 1214-1215

    • NAID

      10007540696

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] PKN delays mitotic timing by inhibition of Cdc25C : Possible involvement of PKN in the regulation of cell division.2001

    • Author(s)
      Misaki, K., Mukai, H., Yoshinaga, C., Oishi, K., Isagawa, T., Takahashi, M., Ohsumi, K., Kishimoto, T., Ono, Y.
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A. 98

      Pages: 125-129

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Neurofilaments of Klotho, the mutant mouse prematurely displaying symptoms resembling human aging.2001

    • Author(s)
      Uchida, A., Komiya, Y., Tashiro, T., Yorifuji, H., Kishimoto, T., Nabeshima, Y., Hisanaga, S.
    • Journal Title

      J. Neurosci. Res. 64

      Pages: 364-370

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inactivation of the checkpoint kinase Cds1 is dependent on cyclin B-Cdc2 kinase activation at the meiotic G2/M-phase transition in Xenopus oocytes.2001

    • Author(s)
      Gotoh, T., Ohsumi, K., Matsui, T., Takisawa, H., Kishimoto, T.
    • Journal Title

      J. Cell Sci. 114

      Pages: 3397-3406

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification and analyses of the Xenopus TERT gene that encodes the catalytic subunit of telomerase.2001

    • Author(s)
      Kuramoto, M., Ohsumi, K., Kishimoto, T., Ishikawa, F.
    • Journal Title

      Gene 277

      Pages: 101-110

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel functional domain of Cdc15 kinase is required for its interaction with Tem1 GTPase in Saccharomyces cerevisiae.2001

    • Author(s)
      Asakawa, K., Yoshida, S., Otake, F., Toh-e, A.
    • Journal Title

      Genetics 157

      Pages: 1437-1450

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Spindle chekpoin in budding yeast.2001

    • Author(s)
      Toh-e, A., Asakawa, K., Yoshida, S.
    • Journal Title

      J. Microbiol. 39

      Pages: 1-10

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Regulation of the localization of Dbf2 and Mob1 during cell division of Saccharomyces cerevisiae.2001

    • Author(s)
      Yoshida, S., Toh-e, A.
    • Journal Title

      Gene Genet Sys. 76

      Pages: 141-147

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel factor required for the SUMO1/Smt3 conjugation of yeast septins.2001

    • Author(s)
      Takahashi, Y., Toh-e, A., Kikkuchi, Y.
    • Journal Title

      Gene 275

      Pages: 223-231

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Yeast Ull1/Siz1 is a novel SUMO-1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates.2001

    • Author(s)
      Takahashi, Y., Kahyo, T., Toh-e, A., Yasuda, H., Kikuchi, Y.
    • Journal Title

      J. Biol. Chem. 276

      Pages: 48973-48977

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Structure and function of cyclin-dependent Pho85 kinase of Saccharomyce cerevisiae.2001

    • Author(s)
      Toh-e, A., Nishizawa, M.
    • Journal Title

      J. Gen. Appl. Microbiol. 47

      Pages: 107-117

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nis1 encoded by YNL078W : a new neck protein of Saccharomyces cerevisiae.2001

    • Author(s)
      Iwase, M., Toh-e, A.
    • Journal Title

      Gene. Genet. Syst. 76

      Pages: 141-147

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Defects in glycosylphosphatidyl inositol(GPI) anchor synthesis activate Hog1 kinase and confer copper-resistance on Saccharomyces cerevisiae.2001

    • Author(s)
      Toh-e, A, Oguchi, T.
    • Journal Title

      Gene. Genet. Syst. 76

      Pages: 393-410

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] T cell-specific loss of Pten leads to defects in central and peripheral tolerance.2001

    • Author(s)
      Suzuki A, Tsukio-Yamaguchi M, Ohteki T, Sasaki T, Kaisho T, Kimura Y, Yoshida R, Wakeham A, Higuchi T, Fukumoto M, Tsubata T, Ohashi P, Koyasu S, Penninger JM, Nakano T, Mak TW.
    • Journal Title

      Immunity 14

      Pages: 523-534

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] SHP-1 requires inhibitory co-receptors to down-modulate B cell an tigen receptor-mediated phosphorylation of cellular substrates.2001

    • Author(s)
      Adachi T, Wienands J, Wakabayashi C, Yakura H, Reth M, Tsubata T.
    • Journal Title

      J. Biol. Chem. 276

      Pages: 26648-26655

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular mechanisms for apoptosis induced by signaling through the B cell antigen receptor.2001

    • Author(s)
      Tsubata, T.
    • Journal Title

      Int. Rev. Immunol. 20

      Pages: 791-803

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A Drosophila MAPKKK, DMEKK1, mediates stress responses through activation of p38 MAPK.2001

    • Author(s)
      Inoue, H. et al.
    • Journal Title

      EMBO J. 20

      Pages: 5421-5430

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] E2F-dependent transcription of the raf proto-oncogene During Drosophila development.2001

    • Author(s)
      Kwon, E-J., et al.
    • Journal Title

      Nucleic Acid. Res. 29

      Pages: 1808-1814

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence.2001

    • Author(s)
      Lin, J., Jinno, S., Okayama, H.
    • Journal Title

      Oncogene 20

      Pages: 2000-2009

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.2001

    • Author(s)
      Tanaka, K., Hao, Z., Kai, M., Okayama, H.
    • Journal Title

      EMBOJ. 20

      Pages: 5779-5790

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inactivation of the checkpoint kinase Cdsl is dependent on cyclin B-Cdc2 kinase activation at the meiotic G2/M-phase transition in Xenopus oocytes.2001

    • Author(s)
      Gotoh, T., Ohsumi, K., Matsui, T., Takisawa, H., Kishimoto, T.
    • Journal Title

      J. Cell Sci. 114

      Pages: 3397-3406

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel functional domain of Cdc15 kinase is required for its interaction with Teml GTPase in Saccharomyces cerevisiae.2001

    • Author(s)
      Asakawa, K., Yoshida, S., Otake, F., Toh-e, A.
    • Journal Title

      Genetics 157

      Pages: 1437-1450

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Spindle Checkpoint Control in Budding Yeast.2001

    • Author(s)
      Toh-e, A., Asakawa, K., Yoshida, S.
    • Journal Title

      J. Microbiol. 39

      Pages: 1-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Regulation of the localization of Dbf2 and Mobl during cell division of Saccharomyces cerevisiae.2001

    • Author(s)
      Yoshida, S., Toh-e, A.
    • Journal Title

      Gene Genet Syst. 76

      Pages: 141-147

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel factor required for the SUMO1/Smt3 conjugation of yeast septins.2001

    • Author(s)
      Takahashi, Y., Toh-e, A., Kikuchi, Y.
    • Journal Title

      Gene 275

      Pages: 223-231

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Yeast U111/Sizl is a novel SUMO-1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates.2001

    • Author(s)
      Takahashi, Y., Kahyo, T., Toh-e, A., Yasuda, H., Kikuchi, Y.
    • Journal Title

      J. Biol. Chem. 276

      Pages: 48973-48977

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Structure and function of cyclin-dependent Pho85 kinase of Saccharomyces cerevisiae.2001

    • Author(s)
      Toh-e, A., Nishizawa, M.
    • Journal Title

      J. Gen. Appl. Microbiol. 47

      Pages: 107-117

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nisi encoded by YNL078W : a new neck protein of Saccharomyces cerevisiae.2001

    • Author(s)
      Iwase, M., Toh-e, A.
    • Journal Title

      Gene. Genet. Syst. 76

      Pages: 335-343

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Defects in glycosylphosphatidylinositol(GPI) anchor synthesis activate Hogl kinase and confer copper-resistance on Saccharomyces cerevisiae.2001

    • Author(s)
      Toh-e, A., Oguchi, T.
    • Journal Title

      Gene. Genet. Syst. 76

      Pages: 393-410

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates.2001

    • Author(s)
      Adachi, T., Wienands, J., Wakabayashi, C, Yakura, H., Reth, M., Tsubata, T.
    • Journal Title

      J. Biol. Chem. 276

      Pages: 26648-26655

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The polyubiquitin gene is essential for meiosis fission yeast.2000

    • Author(s)
      Okazaki K, Okayama H, Niwa O.
    • Journal Title

      Exp Cell Res. 254

      Pages: 143-152

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Role of TGF-beta in EGF-induced transformation of NRK cells is sustaining high-level EGF-signaling.2000

    • Author(s)
      Kizaka-Kondoh S, Akiyama N, Okayama H.
    • Journal Title

      FEBS Lett. 466

      Pages: 160-164

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic Studies with the Fission Yeast Schizosaccharomyces pombe Suggest Involvement of Wee1, Ppa2, and Rad24 in Induction of Cell Cycle Arrest by Human Immunodeficiency Virus Type 1 Vpr.2000

    • Author(s)
      Masuda M, Nagai Y, Oshima N, Tanaka K, Murakami H, Igarashi H, Okayama H.
    • Journal Title

      J Virol. 74

      Pages: 2636-2646

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Fission Yeast Esolp Is Required for Establishing Sister Chromatid Cohesion during S Phase.2000

    • Author(s)
      Tanaka, K., Yonekawa, T., Kawasaki, Y., Kai, M., Furuya, K., Iwasaki, M., Murakami, H., Yanagida, M., Okayama, H.
    • Journal Title

      Molecular And Cellular Biology 20

      Pages: 3459-3469

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A Pcl-like Cyclin Activates the Res2p-Cdc10p Cell Cycle "Start" Transcriptional Factor Complex in Fission Yeast.2000

    • Author(s)
      Tanaka, K., Okayama, H.
    • Journal Title

      Molecular Biology of the Cell 11

      Pages: 2845-2862

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Loop-mediated isothermal amplification of DNA.2000

    • Author(s)
      Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, Hase T.
    • Journal Title

      Nucleic Acids Res. 28

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification and characterization of human Wee1B, a new member of the Wee1 family of Cdk-inhibitory kinases.2000

    • Author(s)
      Nakanishi, M., Ando, H., Watanabe, N., Kitamura, K., Ito, K., Okayama, H., Miyamoto, T., Agui, T., Sasaki, M.
    • Journal Title

      Genes to Cells. 5

      Pages: 839-847

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Fission Yeast Fizzy-related protein srw1p is a G_1-specific promoter of mitotic cyclin B degradation.2000

    • Author(s)
      Yamaguchi, S., Okayama, H., Nurse, P.
    • Journal Title

      The EMBO Journal 19

      Pages: 3968-3977

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Functionalized Fullerene as an Artificial Vector for Transfection.2000

    • Author(s)
      Nakamura, E., Isobe, H., Tomita, N., Sawamura, M., Jinno, S., Okayama, H.
    • Journal Title

      Angew. Chem. Int. Ed. 39

      Pages: 4254-4257

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Residual Cdc2 activity remaining at meiosis I exit is essential for meiotic M-M transition in Xenopus oocyte extracts.2000

    • Author(s)
      Iwabuchi M, Ohsumi K, Yamamoto TM, Sawada W, Kishimoto T.
    • Journal Title

      EMBO J. 19

      Pages: 4513-4523

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A non-proteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M-phase.2000

    • Author(s)
      Nisiyama, A., Tachibana, K., Igarashi, Y, Yasuda, H., Tanahashi, N., Tanaka, K., Ohsumi, K., Kishimoto, T.
    • Journal Title

      Genes Dev. 14

      Pages: 2344-2357

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] c-Mos forces the mitotic cell cycle to undergo meiosis II to produce haploid gametes.2000

    • Author(s)
      Tachibana, K., Tanaka, D., Isobe, T., Kishimoto, T.
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A. 97

      Pages: 14301-14306

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization.2000

    • Author(s)
      Kitazawa H, Iida J, Uchida A, Haino-Fukushima K, Itoh TJ, Hotani H, Ookata K, Murofushi H, Bulinski JC, Kishimoto T, Hisanaga S.
    • Journal Title

      Cell Struc. Funct. 25

      Pages: 33-39

    • NAID

      10006678784

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Brain-derived neurotrophic factor-induced phosphorylation of neurofilament-H subunit in primary culture of embryo rat cortical neurons.2000

    • Author(s)
      Tokuoka H, Saito T, Yorifuji H, Wei F-Y, Kishimoto T, Hisanaga S.
    • Journal Title

      J. Cell Sci. 113

      Pages: 1059-1068

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25.2000

    • Author(s)
      Kusakawa G, Saito T, Onuki R, Ishiguro K, Kishimoto T, Hisanaga S.
    • Journal Title

      J. Biol. Chem. 275

      Pages: 17166-17172

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes.2000

    • Author(s)
      Kawahara H, Kasahara M, Nishiyama A, Ohsumi K, Goto T, Kishimoto T, Saeki Y, Yokosawa H, Shimbara N, Murata S, Chiba T, Suzuki K, Tanaka T.
    • Journal Title

      EMBO J. 19

      Pages: 4144-4153

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Regulation of JNK by Src during Drosophila development.2000

    • Author(s)
      Tateno, M., Nishida, Y., Adachi-Yamada, T.
    • Journal Title

      Science 287

      Pages: 324-327

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A Drosophila Winged-helix nude (Whn)-like transcription factor with essential functions throughout development.2000

    • Author(s)
      Sugimura, I., Adachi-Yamada, T., Nishi, Y., Nishida, Y.
    • Journal Title

      Develp. Growth Differ. 42

      Pages: 237-248

    • NAID

      10016988399

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Transcriptional regulation of the Drosophila raf proto-oncogene by Drosophila STAT during development and in immune response.2000

    • Author(s)
      Kwon E-J, Park H-S, Kim Y-S, Oh E-J, Nishida Y, Matsukage A, Yoo M-A, Yamaguchi M.
    • Journal Title

      J. Biol. Chem. 275

      Pages: 19824-19830

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of a Drosophila homologue of the human myelodysplasia/myeloid leukemia factor (MLF).2000

    • Author(s)
      Ohno K, Takahashi Y, Hirose F, Inoue YH, Taguchi O, Nishida Y, Matsukage A, Yamaguchi M.
    • Journal Title

      Gene 260

      Pages: 133-143

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The polyubiquitin gene is essential for meiosis in fission yeast.2000

    • Author(s)
      Okazaki K, Okayama H, Niwa O.
    • Journal Title

      Exp Cell Res. 254

      Pages: 143-152

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic Studies with the Fission Yeast Schizosaccharomyces pombe Suggest Involvement of Weel, Ppa2, and Rad24 in Induction of Cell Cycle Arrest by Human Immunodeficiency Virus Type 1 Vpr.2000

    • Author(s)
      Masuda M, Nagai Y, Oshima N, Tanaka K, Murakami H, Igarashi H, Okayama H.
    • Journal Title

      J Virol. 74

      Pages: 2636-2646

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A Pcl-like Cyclin Activates the Res2p-CdclOp Cell Cycle "Start" Transcriptional Factor Complex in Fission Yeast.2000

    • Author(s)
      Tanaka, K., Okayama, H.
    • Journal Title

      Molecular Biology of the Cell 11

      Pages: 2845-2862

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification and characterization of human Wee1B, a new member of the Weel family of Cdk-inhibitory kinases.2000

    • Author(s)
      Nakanishi, M., Ando, H., Watanabe, N., Kitamura, K., Ito, K., Okayama, H., Miyamoto, T., Agui, T., Sasaki, M.
    • Journal Title

      Genes to Cells. 5

      Pages: 839-847

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Fission Yeast Fizzy-related protein srwlp is a Gl-specific promoter of mitotic cyclin B degradation.2000

    • Author(s)
      Yamaguchi, S., Okayama, H., Nurse, P.
    • Journal Title

      The EMBO Journal 19

      Pages: 3968-3977

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Residual Cdc2 activity remaining at meiosis I exit is essential for meiotic M-M transition in Xenopus oocyte extracts.2000

    • Author(s)
      Iwabuchi, M., Ohsumi, K., Yamamoto, T.M., Sawada, W., Kishimoto, T.
    • Journal Title

      EMBOJ. 19

      Pages: 4513-4523

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A non-proteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M-phase.2000

    • Author(s)
      Nishiyama, A., Tachibana, K., Igarashi, Y., Yasuda, H., Tanahashi, N., Tanaka, K., Ohsumi, K., Kishimoto, T.
    • Journal Title

      Genes Dev. 14

      Pages: 2344-2357

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization.2000

    • Author(s)
      Kitazawa H, Iida J, Uchida A, Haino-Fukushima K, Itoh TJ, Hotani H, Ookata K, Murofushi H, Bulinski J.C., Kishimoto T, Hisanaga S.
    • Journal Title

      Cell Struc. Funct. 25

      Pages: 33-39

    • NAID

      10006678784

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Brain-derived neurotrophic factor-induced phosphorylation of neurofilament-H subunit in primary culture of embryo rat cortical neurons.2000

    • Author(s)
      Tokuoka, H., Saito, T., Yorifuji, H., Wei, F-Y., Kishimoto, T., Hisanaga, S.
    • Journal Title

      J. Cell Sci. 113

      Pages: 1059-1068

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25.2000

    • Author(s)
      Kusakawa, G., Saito, T., Onuki, R., Ishiguro, K., Kishimoto, T., Hisanaga, S.
    • Journal Title

      J. Biol. Chem. 275

      Pages: 17166-17172

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes.2000

    • Author(s)
      Kawahara, H., Kasahara, M., Nishiyama, A., Ohsumi, K., Goto, T., Kishimoto, T., Saeki, Y., Yokosawa, H., Shimbara, N., Murata, S., Chiba, T., Suzuki, K., Tanaka, T.
    • Journal Title

      EMBO J. 19

      Pages: 4144-4153

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] 細胞周期集中マスター(北川雅敏編)2006

    • Author(s)
      岸本健雄(分担)
    • Total Pages
      154
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] 発生における細胞増殖制御2004

    • Author(s)
      竹内隆, 岸本健雄(編集)
    • Total Pages
      198
    • Publisher
      シュプリンガーフェアラーク東京
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] 日本生化学会・バイオサイエンスの新世紀 第6巻 「細胞の誕生と死」(長田重一, 山本雅編)2001

    • Author(s)
      岸本健雄(分担)
    • Total Pages
      198
    • Publisher
      共立出版
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Publications] Iwai H, Kohsaka H, et al.: "Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis"J Immunol. 171(9). 2848-2854 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Nonomura Y, Kohsaka H. et al.: "Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis"J Immunol. 171(9). 4913-4919 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Nishio J, Kohsaka H, et al.: "Development of TCRB CDR3 length repertoire of human lymphocytes"Int Immunol. 16(3). 423-431 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Terada Y, Tanaka H, et al.: "Wnt4 Expression and function of the developmental gene Wnt-4 during experimental acute renal failure in rats"J Amer Soc Nephrol. 14(5). 1223-1233 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Shimamura H, Terada Y, et al.: "The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibited apoptosis in vitro via NF-kB and Bad"J Amer Soc Nephrol. 14(6). 1427-1434 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Asai T, Terada Y, et al.: "Pathogenesis of nephrogenic diabetes insipidus by aquaporin-2 C-terminus mutations"Kidney Int.. 64(1). 2-10 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Tanaka, T., et al.: "In vivo analysis of the cyclin D1 promoter during early embryogenesis in Xenopus."Cell Structure and Function. 28. 165-177 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Okano-Uchida, T., et al.: "Distinct regulators for P1kl activation in starfish meiotic and early embryonic cycles"EMBO J.. 22. 5633-5642 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Terasaki, M., et al.: "Localization and dynamics of Cdc2-cyclin B during meiotic reinitiation in starfish oocytes."Mol.Biol.Cell. 14. 4685-4694 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kishimoto, T.: "Cell cycle control during meiotic maturation."Curr.Opin.Cell Biol.. 15. 654-663 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Uchida, A., et al.: "Morphological and biochemical changes of neurofilaments in aged rat sciatic nerve axons."J.Neurochem.. 88. 735-745 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kishimoto, T.: "More than G1 or G2 arrest : Useful starfish oocyte system for investigating skillful MAP kinase."Biol.Cell. 96(in press). (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Miura, Y., et al.: "Susceptibility to killer T cells of gastric cancer cells enhanced by Mitomycin-C involves induction of ATBF1 and activation of p21 (Waf1/Cip1) promoter."Microbiol.Immunol. 48. 137-145 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Fujita, F., et al.: "Identification of NAP1, a regulatory subunit of I_B kinase-related kinases that potentiates NF-_B signaling."Mol.Cell.Biol.. 23. 7780-7793 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Ishimi, Y., et al.: "Identification of MCM4 as a target of the DNA replication checkpoint system."J.Biol.Chem.. 278. 24644-24650 (2003)

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      2003 Annual Research Report
  • [Publications] Kobayashi, S., et al.: "Stretch-induced IL-6 secretion from endothelial cells requires NF-_B activation"Biochem.Biophys.Res.Commun.. 308. 306-312 (2003)

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      2003 Annual Research Report
  • [Publications] Li, S.F., et al.: "Genomic structure and characterization of the promoter region of the human NAK gene."Gene. 304. 57-64 (2003)

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      2003 Annual Research Report
  • [Publications] Kwon, E., et al.: "Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster and virilis."Gene. 309. 101-116 (2003)

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      2003 Annual Research Report
  • [Publications] Suzuki, A., et al.: "Critical roles of Pten in B cell homeostasis and immunoglobulin class awitch recombination"J.Exp.Med.. 197. 657-667 (2003)

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      2003 Annual Research Report
  • [Publications] Hokazono, Y., et al.: "Inhibitory co-receptors activated by antigens but not by anti-immunoglobulin heavy chain antibodies install requirement of co-stimulation through CD40 for surviva and proliferation of B cells."J.Immunol. 171. 1835-1843 (2003)

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      2003 Annual Research Report
  • [Publications] Hirai, H., et al.: "Involvement of cell cycle progression in survaival signaling through CD40 inB lymphocyte line WEHI-231."Cell.Death.Differ.. 11. 261-269 (2004)

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      2003 Annual Research Report
  • [Publications] Matsuzaka, T., et al.: "Insulin-independent induction of sterol regulatory element-binding protein-lc expression in the livers of streptozotocin-treated mice."Diabetes.. 53(3). 560-569 (2004)

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      2003 Annual Research Report
  • [Publications] Yokoo, T., et al.: "p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus."J Biol Chem.. 278(52). 52919-52923 (2003)

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  • [Publications] Fukumoto A.: "Prognostic significance of localized p27Kipl and potential role of Jabl/CSNS in pancreatic cancer"Oncol Rep.. 11. 277-284 (2004)

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      2003 Annual Research Report
  • [Publications] Furukawa, K., et al.: "Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila."J.Cell Sci.. 116. 3811-3823 (2003)

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      2003 Annual Research Report
  • [Publications] Toh-e A., et al.: "Ras recruits mitotic exit regulator Ltel to the bud cortex in budding yeast."J.Cell Biol.. 161. 889-897 (2003)

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      2003 Annual Research Report
  • [Publications] Takahashi Y., et al.: "Comparative analysis of yeast PIAS- type SUMO ligases in vitro and in vivo."J.Biochem.. 133. 425-422 (2003)

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      2003 Annual Research Report
  • [Publications] Kaida D., et al.: "Rsp5-Bul 1/2 complex is necessary for the HSE-mediated gene expression in budding yeast."Biochem.Biophys.Res.Commun.. 306. 1037-1041 (2003)

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      2003 Annual Research Report
  • [Publications] Sato, N., et al.: "Phosphorylation-regulated degradation of the yeast Ssklp response regulator by the ubiquitin-proteasome system."Mol.Cell.Boil.. 23. 6662-6671 (2003)

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  • [Publications] Tanaka, H. et al.: "The fission Yeast pfh1^+ gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phase"Nucleic Acids Research. 30・22. 4728-4739 (2002)

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  • [Publications] Hiroi, N. et al.: "Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation"The EMBO Journal. 21・19. 5235-5244 (2002)

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      2002 Annual Research Report
  • [Publications] Jinno, S. et al.: "Cdc6 requires anchorage for its expression"Oncogene. 21. 1777-1784 (2002)

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      2002 Annual Research Report
  • [Publications] Chen, Q. et al.: "Overexpression of Cdk6-cyclin D3 highly sensitizes cells to physical and chemical transformation"Oncogene. 22. 992-1001 (2003)

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  • [Publications] Uesono, Y. et al.: "Transient inhibition of translation initiation by osmotic stress"J. Biol. Chem.. 277. 13848-13855 (2002)

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  • [Publications] Yoshida, S. et al.: "Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiae"Curr. Biol.. 12. 944-950 (2002)

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  • [Publications] Saeki, Y. et al.: "Ubiquitin-like proteins and Rpn10 play cooperative roles in ubiquitindependent proteolysis"Biochem. Biophys. Res. Commun.. 293. 986-992 (2002)

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      2002 Annual Research Report
  • [Publications] Kaida, D., et al.: "Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression"Genes Cells. 7. 543-552 (2002)

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  • [Publications] Yoshida, S. et al.: "Budding yeast Cdc5 phosphorylates Net1 and assists Cdc14 release from the nucleolus"Biochem. Biophys. Res. Commun.. 294. 687-691 (2002)

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      2002 Annual Research Report
  • [Publications] Asakawa, K. et al.: "A defect in KAP104 alleviates the requirement of the MEN (Mitotic Exit Network) gene function in Saccharomyces cerevisiae"Genetics. 162. 1545-1556 (2002)

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      2002 Annual Research Report
  • [Publications] Itoh, K. et al.: "Complex formation with the class IV myosin Myo2p is essential for Ypt11p, a rab-type small GTPase, to facilitate the Myo2p function for mitochondrial distribution in the budding yeast"Mol. Cell. Biol.. 22. 7744-7757 (2002)

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      2002 Annual Research Report
  • [Publications] Toh-e, A. et al.: "Genetic charactenization of genes encoding enzymes catalyzing addition of phosphoethanolamine to the glucosylphosphatidylinositol anchor in Saccharomyces cerevisiae"Genes Genet Sys.. 77. 309-322 (2002)

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      2002 Annual Research Report
  • [Publications] Saeki, Y. et al.: "Identification of ubiquitin-like protein-binding subunits of the 26S proteasome"Biochem. Biophys. Res. Commun. 296. 813-819 (2002)

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      2002 Annual Research Report
  • [Publications] Tone, Y. et al.: "Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae"Genes Dev.. 16. 3142-3157 (2002)

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      2002 Annual Research Report
  • [Publications] Mizuno, T. et al.: "Drosophila myosin phosphatase and its role in dorsal closure"Development. 129. 1215-1223 (2002)

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      2002 Annual Research Report
  • [Publications] Kwon, E.-J.et al.: "Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster"Gene. (in press). (2003)

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      2002 Annual Research Report
  • [Publications] Sekiya, -K.M. et al.: "Dissection of Upstream Regulatory Components of the Rho1p Effector, 1,3-β-Glucan Synthase, in Saccharomyces cerevisiae"Genetics. 162. 663-761 (2002)

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      2002 Annual Research Report
  • [Publications] Utsugi, T. et al.: "Movement of yeast 1,3-β-glucan synthase on the surface of the plasma membrane"Gene to Cells. 7. 1-9 (2002)

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      2002 Annual Research Report
  • [Publications] Mizutani, R., et al.: "Protein-splicing reaction via a thiazolidine intermediate : crystal structure of the VMA1-derived endonuclease bearing the N-and C-terminal propeptides"J. Mol. Biol.. 316. 919-929 (2002)

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      2002 Annual Research Report
  • [Publications] Dijkgraaf, G.J.P. et al.: "Involvement of Saccharomyces cerevisiae Fks1p in β-1,6-glucan biosynthesis"Yeast. 19. 671-690 (2002)

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      2002 Annual Research Report
  • [Publications] Nogami, S. et al.: "Karyopherin-mediated Nuclear Import of the Homing Endonuclease, VDE, Is Required for Self-propagation of the Coding Region"Mol. Cell Biol.. 23. 1726-1736 (2002)

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      2002 Annual Research Report
  • [Publications] Okuda Y. et al.: "Occurrence, horizonatal transfer and degeneration of VDE intein family in saccharomycete yeasts"Yeast. (in press). (2003)

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      2002 Annual Research Report
  • [Publications] Abe, M.et al.: "Lack of GTP-bound Rho1p in Secretory Vesicles of Saccharomyces cerevisiae"J. Cell Biol.. (in press). (2003)

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      2002 Annual Research Report
  • [Publications] Ohtani, Sano, F. et al.: "Development of image processing program for yeast cell morphology"J. Bioinfo Comp. Biol.. (in press). (2003)

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  • [Publications] Tachibana, M. et al.: "G9a histone methyltransferase plays a dominant role for euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis"Genes and Development. 16. 1779-1791 (2002)

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  • [Publications] Xin, Z.et al.: "Role of histone methyltransferase G9a in CpG methylation of the Prader-Willi syndrome imprinting center"J. Biol. Chem.. (in press). (2003)

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  • [Publications] Higuchi, T. et al.: "Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease"J. Immunol.. 168. 9-12 (2002)

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  • [Publications] Wakabayashi, C. et al.: "A distinct signaling pathway used by the IgG-containing B cell antigen receptor"Science. 298. 2392-2395 (2002)

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  • [Publications] Okumura, E. et al.: "Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition"Nature Cell Biol.. 4. 111-116 (2002)

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  • [Publications] Iwabuchi, M. et al.: "Coordinated regulation of M phase exit and S phase entry by the Cdc2 activity level in the early embryonic cell cycle"Dev. Biol.. 243. 34-43 (2002)

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  • [Publications] Saito, T. et al.: "Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation"J. Neurosci.. 23. 1189-1194 (2003)

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  • [Publications] Okano-Uchida, T. et al.: "Distinct regulators for Plk activation in meiotic and early embryonic cycles"EMBO J.. (in press). (2003)

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  • [Publications] Higashiyama, H. et al.: "Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced eye degeneration"Cell Death Differ.. 9. 264-273 (2002)

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  • [Publications] Hirose, F. et al.: "Drosophila Mi-2 negatively regulates dDREF by inhibiting its DNA binding activity"Mol. Cell. Biol.. 22. 5182-5193 (2002)

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      2002 Annual Research Report
  • [Publications] Hwang M.-S.et al.: "The Caudal homeodomain protein activates Drosophila E2F gene expression"Nucleic Acids Res.. 23. 5029-5035 (2002)

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  • [Publications] Kwon, E. et al.: "Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster and virilis"Gene. (in press). (2003)

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      2002 Annual Research Report
  • [Publications] Jinno, S. et al.: "Oncogenic cell cycle start control"Mut. Res.. 477. 23-29 (2001)

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      2001 Annual Research Report
  • [Publications] Lin, J.et al.: "Cyclin D3-Cdk6 complex evades inhibition by inhibitor proteins and uniquely controls cell's growth competence"Oncogene. 20. 2000-2009 (2001)

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      2001 Annual Research Report
  • [Publications] Tanaka, K. et al.: "Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism"EMBO J.. 20. 5779-5790 (2001)

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  • [Publications] Tsukahara, K. et al.: "Anticancer agent e7O7O inhibits amino acid and uracil transport in fission yeast"Mol. Pharmacol. 60. 1254-1259 (2001)

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  • [Publications] Isobe, H. et al.: "Synthesis and transfection capability of multi-functionalized fullerene polyamine"Chem. Lett.. 12. 1214-1215 (2001)

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      2001 Annual Research Report
  • [Publications] Jinno, S. et al.: "Cdc6 requires anchorage for its expression"Oncogene. (in press).

    • Related Report
      2001 Annual Research Report
  • [Publications] Gotoh, T. et al.: "Inactivation of the checkpoint kinase Cds 1 is dependent on cyclin B-Cdc2 kinases activation at the meiotic・・・"J. Cell Sci. 114. 3397-3406 (2001)

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  • [Publications] Okumura, E. et al.: "Akt inhibits Myt1 in the signal ling pathway that leads to meiotic G2/M-phase transition"Nature Cell Biol.. 4. 111-116 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Iwabuchi, M. et al.: "Coordinated regulation of M phase exit and S phase entry by the Cdc2 activity level in the early embryonic cell cycle"Dev. Biol.. (in press).

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      2001 Annual Research Report
  • [Publications] Iwase, M., Toh-e, A.: "Nis1 encoded by YNLO78W : a new neck protein of Saccharomyces cerevisiae"Genes Genet Syst. 76. 335-343 (2001)

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      2001 Annual Research Report
  • [Publications] Uesono, Y.Toh-e, A.: "Transient inhibition of translation initiation by osmotic stress"J Biol. Chem.. (in press).

    • Related Report
      2001 Annual Research Report
  • [Publications] Takahashi, Y. et al.: "A novel factor required for the SUMO1/Smt3conjugation of yeast septins"Gene. 275. 223-231 (2001)

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      2001 Annual Research Report
  • [Publications] Takahashi, Y. et al.: "Veast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme・・・"J Biol Chem.. 276. 48973-48977 (2001)

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  • [Publications] Yoshida, S., Toh-e, A.: "Regulation of the localization of Dbf2 and Mob1 during cell division fo Saccharomyces cerevisiae"Genes Genet Syst. 76. 141-147 (2001)

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  • [Publications] Takeuchi, J., Toh-e, A.: "Genetic dissection of th yeast 26S proteasome : cell cycle defects caused by the Deltarpn9 mutation"Biochimie. 83. 333-340 (2001)

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  • [Publications] Asakawa, K. et al.: "A novel functional domain of Cdc15 kinase is required for its interaction with Tem1 GTPase in Saccharomyces cerevisiae"Genetics. 157. 1437-1450 (2001)

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  • [Publications] Tsubata, T. et al.: "Regulation of B cell antigen receptor signaling by CD72"Sprnger-Verlag. 123-128 (2001)

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      2001 Annual Research Report
  • [Publications] Suzuki, A, etal.: "Tcell-specific loss of Pten leads to defects in central and peripheral tolerance"Immunity. 14. 523-534 (2001)

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      2001 Annual Research Report
  • [Publications] Adachi, T. et al.: "SHP-1 requires inhibitory co-receptors to downmodulate B cell antigen receptor-mediated phossphorylation of cellular ・・・"J Biol. Chem.. 276. 26648-26655 (2001)

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  • [Publications] Tsubata, T.: "Molecular mechanisms for apoptosis induced by signaling through the B cell antigen recptor"Int. Rev. Immunol. 20. 791-803 (2001)

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      2001 Annual Research Report
  • [Publications] Higuchi, T. et al.: "Cutting Edge : Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmunedisease"J. Immunol. 168. 9-12 (2002)

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      2001 Annual Research Report
  • [Publications] kwon, Y.-J.et al.: "E2F-dependent transcription of the raf proto-oncogene during Drosophila development"Nucleic Acid. Res.. 29. 1808-1814 (2001)

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      2001 Annual Research Report
  • [Publications] lnoue, H. et al.: "A Drosopila MAPKKK, D-MEKK1, mediates stress responses through activation of p38 MAPK"EMBO. J.. 19. 5421-5430 (2001)

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      2001 Annual Research Report
  • [Publications] Mizuno, T. et al.: "Drosophila myosin phosphatase and its role in dorsal closure"Development. (in press).

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      2001 Annual Research Report
  • [Publications] Wada, S. et al.: "DNA polymerasee is required for coordinated and efficient chromosomal DNA replication in Xenpous egg extracts"Proc. Natl. Acad. Sci. USA. 98. 4978-4983 (2001)

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      2001 Annual Research Report
  • [Publications] Gotoh, T. et al.: "Inactivation of the checkpoint kinase Cds1 is dependent on cyclin B-Cdc2 kinase activation at the meiotic G2/M/phase"J. Cell Sci.. 114. 3397-3406 (2001)

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      2001 Annual Research Report
  • [Publications] yasui, Y. et al.: "Protein kinases required for segregation of vimentin filaments in mitotic process"Oncogene. 20. 2868-2876 (2001)

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      2001 Annual Research Report
  • [Publications] Inada, H. et al.: "Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD"M. J. Cell Biol.. 155. 415-425 (2001)

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      2001 Annual Research Report
  • [Publications] Goto, H. et al.: "Aurora-B phosphorylates histone H3 at serine 28 with regard to the mitosic chromosome condensation"Genes Cells. 7. 11-17 (2002)

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      2001 Annual Research Report
  • [Publications] Masuda,M. et al.: "Genetic Studies with the Fission Yeast Schizosaccharomyces pombe Suggert Involvement of Wee1, Ppa2, and Rad24 in Induction of Cell Cycle Arrest by Human Immunodeficiency Virus Type 1 Vpr"J.Virol. 74. 2636-2646 (2000)

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      2000 Annual Research Report
  • [Publications] Tanaka,K. et al.: "Fission yeast Eso1p is required for establishing chromatid cohesion during S phase"Mol.Cell.Biol.. 20. 3459-3469 (2000)

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      2000 Annual Research Report
  • [Publications] Notomi,T. et al.: "Loop-mediated isothermal amplification of DNA"Nuc.Acids Res.. 28. e63 (2000)

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      2000 Annual Research Report
  • [Publications] Yamaguchi,S. et al.: "Fission yeast Fizzy-related protein Srw1p is a G(1)-specific promoter of mitotic cyclin B degradation"EMBO J.. 19. 3968-3977 (2000)

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      2000 Annual Research Report
  • [Publications] Tanaka,K. et al.: "A Pcl-like cyclin activates the Res2p-Cdc10p cell cyc 'start' transcriptional factor in fission yeast"Mol Biol.Cell. 11. 2845-2862 (2000)

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      2000 Annual Research Report
  • [Publications] Nakamura,E. et al.: "Funtionalized fullerene as an artificial vector for transfection"Angew.Chem.. 112. 4424-4427 (2000)

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      2000 Annual Research Report
  • [Publications] Jinno,S. et al.: "Oncogenic cell cycle start control"Mut.Res.. (in press).

    • Related Report
      2000 Annual Research Report
  • [Publications] Lin,J. et al.: "Cyclin D3-Cdk6 complex evades inhibition by inhibitior proteins and uniquely controls cell's growth competence"Oncogene. (in press).

    • Related Report
      2000 Annual Research Report

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Published: 2001-04-01   Modified: 2018-03-28  

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