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STUDIES OF HUMAN BRAIN FUNCTIONS I USING MULTI-CHANNEL LARGE MEG DEVICE AND MICRO-SQUID

Research Project

Project/Area Number 12470145
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurology
Research InstitutionOKAZAKI NATIONAL RESEARCH INSTITUTES

Principal Investigator

KAKIGI Ryusuke  OKAZAKI NATIONAL RESEARCH INSTITUTE, DEPARTMENT OF INTEGRATIVE PHYSIOLOGY, PROFESSOR, 生理学研究所, 教授 (10145196)

Co-Investigator(Kenkyū-buntansha) KOYAMA Sachiko  OKAZAKI NATIONAL RESEARCH INSTITUTE, DEPARTMENT OF INTEGRATIVE PHYSIOLOGY, ASSISTANT PROFESSOR, 生理学研究所, 助手 (40270483)
WATANABE Shoko  OKAZAKI NATIONAL RESEARCH INSTITUTE, DEPARTMENT OF INTEGRATIVE PHYSIOLOGY, ASSISTANT PROFESSOR, 生理学研究所, 助手 (00321612)
KANEOKE Yoshiki  OKAZAKI NATIONAL RESEARCH INSTITUTE, DEPARTMENT OF INTEGRATIVE PHYSIOLOGY, ASSOCIATE PROFESSOR, 生理学研究所, 助教授 (20280589)
Project Period (FY) 2000 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥9,200,000 (Direct Cost: ¥9,200,000)
Fiscal Year 2002: ¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2001: ¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2000: ¥4,600,000 (Direct Cost: ¥4,600,000)
KeywordsMAGNETOENCEPHALOGRAPHY / ELECTROENCEPHALOGRAPHY / PAIN / VISION / AUDITORY / FACE / BRAIN / HUMANS / 超小型 / 高分解能 / 磁場 / micro / SQUID / 顔 / 認知 / 臨床応用 / 基礎研究 / 脳磁図、 / 脳神経、 / 顔、 / 言語、 / 視覚、 / 体性感覚、 / 基礎研究、
Research Abstract

This is the report of activities in our department between 200 and 2002.. During this period, we mainly investigated brain functions by magnetoencephalography (MEG) and electroencephalography (EEG), but started to use 3-T functional magnetic resonance imaging (fMRI) in cooperation with the Department of Cerebral Research (Chairperson Prof. Norihiro Sadato).
One of the biggest news items during this period was that we installed a new whole-head MEG machine, VectorView, made by Neuromag in Augus, 2002. After some minor troubles, the new machine is now working well. We hope to discover and report new and important findings using this new tool.
As pioneers of MEG study in Japan, we will do our best to make progress in MEG investigation, though we always face and have to solve many misunderstandings by researchers in other scientific fields. Cooperative studies with researchers in other fields such as functional MRI and PET are, of course, necessary to resolve the complicated but fascinating problems of the human brain.

Report

(4 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • Research Products

    (27 results)

All Other

All Publications (27 results)

  • [Publications] Wang X, Kakigi R, et al.: "Effects of sleep on pain-related somatosensory evoked potentials in humans."Neuroscience Research. 45. 53-57 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Inui K, Kakigi R, et al.: "A comparative magnetoencephalographic study of cortical activations evoked by noxious and innocuous stimulations."Neuroscience. 120. 235-248 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Wang X, Kakigi R, et al.: "Effects of sleep on pain related somatosensory evoked magnetic fields in humans"Brain Research Cognitive Brain Research. 17. 388-399 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Qiu Y, Kakigi R, et al.: "Microneurographic study of C fiber discharges induced by CO_2 laser stimulation in humans."Neuroscience Letters. 353. 25-28 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Inui K, Kakigi R, et al.: "Pain processing within the primary somatosensory cortex in humans."European Journal of Neuroscience. 17. 2859-2866 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 緒方 宣邦, 柿木 隆介: "痛みの基礎と臨床"真興交易出版、東京. 310 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Watanabe S, Kakigi R, Puce A: "The spatiotemporal dynamics of the face inversion effect : a magneto-and electro-encephalographic study."Neuroscience.. 116. 879-895 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koyama S, Kakigi R et al.: "Cortical evidence of the perceptual backward masking effect on /l/ and /r/ sounds from a following vowel in Japanese speakers."Neuroimage,. 18. 962-974 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Inui K, Kakigi R et al.: "A comparative magnetoencephalographic study of cortical activations evoked by noxious and innocuous somatosensory stimulations."Neuroscience. 120. 235-248 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Fujioka T, Kakigi R et al.: "Tonotopic representation of missing fundamental complex sounds in the human auditory cortex"European Journal of Neuroscience. 18. 432-440 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Inui K, Kakigi R et al.: "Pain processing within the primary somatosensory cortex in humans."European Journal of Neuroscience. 17. 2859-2866 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Wasaka T, Kakigi R et al.: "Gating of somatosensory evoked magnetic fields during the preparatory period of self initiated finger movement"Neuroimage.. 20. 1830-1838 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Sofue A, Kaneoke Y, Kakigi R.: "Physiological evidence of interaction of first and second-order motion processes in the human visual system A magnetoencephalographic study."Human Brain Mapping. 20. 158-167 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Tran TD, Kakigi R et al.: "Conduction velocity of the spinothalamic tract following CO_2 laser stimulation of C-fibers in humans"Pain. 95・1. 125-131 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Inui K, Kakigi R et al.: "Preferential stimulation of A delta fibers by intra-epidermal needle electrode in humans"Pain. 96・2. 247-252 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Tran TD, Kakigi R et al.: "Cerebral activation by the signals ascending through unmyelinated C-fibers in humans : a magnetoencephalographic study"Neuroscience. 113・2. 375-386 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Watanabe S, Kakigi R et al.: "Gaze direction affects face perception in humans"Neuroscience Letters. 325・2. 163-166 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Qiu Y, Kakigi R et al.: "Effects of attention, distraction and sleep on CO_2 laser evoked potentials related to C-fibers in humans"Clinical Neurophysiology. 113・9. 1579-1585 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Watanabe S, Kakigi R et al.: "The spatiotemporal dynamics of the face inversion effect : a magneto-and electro-encephalographic study"Neuroscience. 116・3. 879-895 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Nihashi T, Kakigi R et al.: "Representation ofthe ear in human primary somatosensory cortex"Neuroimage. 13・2. 295-304 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Tran TD, Kakigi R et al.: "A new method for measuring conduction velocities of Aβ-, Aδ-and C-fibers in humans following electrical and CO_2 laser stimulation"Neuroscience Letters. 301・3. 187-190 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Watanabe S, Kakigi R et al.: "Occipitotemporal activity elicited by viewing eye movements : a magnetoencephalographic study"Neuroimage. 13・2. 351-363 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Sekiguchi T, Kakigi R et al.: "The effect of stimulus repetition on cortical magnetic responses evoked by words and nonwords"Neuroimage. 14・1. 118-128 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Lam K, Kakigi R et al.: "Attention and visual interference affect somatosensory perception : a magnetoencephalographic study"Neuroscience. 104・3. 689-703 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Hoshiyama M, Kakigi R: "Two evoked responses with different recovery functions in the primary somatosensory cortex in humans"Clinical Neurophysiology. 112・7. 193-191 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kakigi R et al: "The somatosensory evoked magnetic fields."Progress in Neurobiology. 61. 495-523 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kakigi R et al: "Pain-related somatosensory evoked potentials."Journal of Clinical Neurophysiology. 17. 295-308 (2000)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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