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Application of dynamic virtual reality visualization technology for real-time tumor-tracking radiation therapy

Research Project

Project/Area Number 12470182
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionHOKKAIDO UNIVERSITY

Principal Investigator

SHIRATO Hiroki  Hokkaido Univ., School of Med. Hospital, Asso. Prof., 医学部・附属病院, 助教授 (20187537)

Co-Investigator(Kenkyū-buntansha) IFUKUBE Touru  Hokkaid Univ. Research Institute for Electronic Science, Prof., 電子科学研究所, 教授 (70002102)
Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥8,900,000 (Direct Cost: ¥8,900,000)
Fiscal Year 2001: ¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 2000: ¥7,000,000 (Direct Cost: ¥7,000,000)
Keywordsradiotherapy / respiratory movement / set-up error / real-time tracking / pattern recognition / virtual reality / cancer treatment / four-dimensional radiotherapy / ヴァーチャルリアリテイ技術 / セットアッブ誤差 / ヴァーチャルリアリテイ
Research Abstract

To improve the accuracy of radiotherapy for tumors moving in the body, how to use virtual reality technology was investigated. For the registration of real-space and virtual-space, a 2.0 mm gold marker was developed and three of them were inserted near the tumor in human body. Tow fluoroscopic x-ray cameras were installed in the treatment room. The three dimensional position of the markers can be calculated by the two cameras with an accuracy of 0.5 mm. Translation, rotation, and distortion of the tumor can be all calculated at the start of radiotherapy and the position of the tumor can be adjusted before the radiotherapy accordingly. Automatic patter recognition technology with real-time comparison of the three-dimensional co-ordinates of virtual "planned marker" with the three-dimensional co-ordinates of "actual marker" every 0.03 seconds made it possible to irradiate lung and liver tumors only when they are located at the planned position within an accuracy of 2 mm. Tumors very close to the critical normal structure such as spinal cord for spinal schwannoma or rectum for prostate carcinoma, the system was useful to improve dose distribution. Lung and liver tumors were well controlled by the system using higher radiation dose than conventional radiotherapy. Virtual reality technology with the aid of pattern recogtion technology was revealed to be an important tool for the four-dimensional (time and space) treatment planning and real-time tumor tracking radiotherapy.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (22 results)

All Other

All Publications (22 results)

  • [Publications] Shimizu S: "Detection of lung tumor movement in real-time tumor-tracking radiotherapy"Int J Radiat Oncol Biol Phys. 51(2). 304-310 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Aoyama H: "Induction Chemotherapy Followed by Low-Dose Involved-Field Radiotherapy for Intracranial Germ Cell Tumors"J Clin Oncol. 20(3). 857-865 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Sakamoto T: "Annual rate of hearing loss falls after fractionated stereotactic irradiation for vestibular schwannoma"Radiother Oncol. 60(1). 45-48 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Aoyama H: "Magnetic resonance imaging system for three-dimensional conformal radiotherapy and its impact on gross tumor volume delineation of central nervous system tumors"Int J Radiat Oncol Biol Phys. 50(3). 821-827 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto S: "Remote verification in radiotherapy using digitally reconstructed radiography(DRR) and portal images : a pilot study"Int J Radiat Oncol Biol Phys. 50(2). 579-585 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Aoyama H: "Treatment outcome of single or hypofactionated single-isocentric stereotactic irradiation(STI) using a linear accelerator for intracranial arteriovenous malformation"Radiother Oncol.. 59(3). 323-328 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Shimizu S.: "Detection of lung tumor movement in real-time tumor-tracking radiotherapy."Int J Radiat Oncol Biol Phys. 51(2). 304-10 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Aoyama H.: "Induction chemotherapy followed by low-dose involved-field radiotherapy for intracranial germ cell tumors."J Clin Oncol. 20(3). 857-65 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Sakamoto T.: "Annual rate of hearing loss falls after fractionated stereotactic irradiation for vestibular schwannoma."Radiather Oncol. 60(1). 45-8 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto S.: "Remote verification in radiotherapy using digitally reconstructed radiography (DRR) and portal images : a pilot study."Int J Radiat Oncol Biol Phys. 50(2). 579-85 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Shimizu S.: "Detection of lung tumor movement in real-time tumor-tracking radiotherapy"Int J Radiat Oncol Biol Phys. 51(2). 304-340 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Aoyama H.: "Induction Chemotherapy Followed by Low-Dose Involved-Field Radiotherapy for Intracranial Germ Cell Tumors"J Clin Oncol. 20(3). 857-865 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Sakamoto T.: "Annual rate of hearing loss falls after fractionated stereotactic irradiation for vestibular schwannoma"Radiother Oncol. 60(1). 45-48 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Aoyama H.: "Magnetic resonance imaging system for three-dimensional conformal radiotherapy and its impact on gross tumor volume delineation of central nervous system tumors"Int J Radiat Oncol Biol Phys. 50(3). 821-827 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Hashimoto S.: "Remote verification in radiotherapy using digitally reconstructed radiography (DRR) and portal images : a pilot study"Int J Radiat Oncol Biol Phys. 50(2). 579-585 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Aoyama H.: "Treatment outcome of single or hypofractionated single-isocentric stereotactic irradiation (STI) using a linear accelerator for intracranial arteriovenous malformation"Radiother Oncol. 59(3). 323-328 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Shimizu S,: "Use of an implanted marker and real-time tracking of the marker for the positioning of prostate and bladder cancers."Int J Radiat Oncol Biol Phys. 48(5). 1591-7 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Shirato H,: "Physical aspects of a real-time tumor-tracking system for gated radiotherapy."Int J Radiat Oncol Biol Phys. 48(4). 1187-95 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Shirato H,: "Fractionated stereotactic radiotherapy for vestibular schwannoma(VS) : comparison between cystic-type and solid-type VS."Int J Radiat Oncol Biol Phys. 48(5). 1395-401 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Nishioka T,: "Three-dimensional small-volume irradiation for residual or recurrent nasopharyngeal carcinoma."Int J Radiat Oncol Biol Phys. 48(2). 495-500 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Shimizu S,: "High-speed magnetic resonance imaging for four-dimensional treatment planning of conformal radiotherapy of moving body tumors."Int J Radiat Oncol Biol Phys. 48(2). 471-4 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Shirato H,: "Four-dimensional treatment planning and fluoroscopic real-time tumor tracking radiotherapy for moving tumor."Int J Radiat Oncol Biol Phys. 48(2). 435-42 (2000)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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