• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of oral and maxillofacial distraction osteogenesis using the floating bone method

Research Project

Project/Area Number 12470375
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Plastic surgery
Research InstitutionThe University of Tokyo

Principal Investigator

TAKATO Tsuyoshi  Tokyo University, Dep of Oral and Maxillofacial Surgery, Professor, 医学部・附属病院, 教授 (90171454)

Co-Investigator(Kenkyū-buntansha) EGUCHI Tomoaki  Tokyo University, Dep of Oral and Maxillofacial Surgery, Assistant Professor, 医学部・附属病院, 講師 (00302688)
SUSAMI Takafumi  Tokyo University, Dep of Oral and Maxillofacial Surgery, Associate Professor, 医学部・附属病院, 助教授 (80179184)
NAKATSUKA Takashi  Saitama Medical University, Dep pf Plastic Surgery, Professor, 附属病院, 教授 (80198134)
MIYATA Teruo  Koken Co. Ltd., Manage, Researcher, 研究開発本部, 部長(研究職)
Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥13,300,000 (Direct Cost: ¥13,300,000)
Fiscal Year 2001: ¥4,300,000 (Direct Cost: ¥4,300,000)
Fiscal Year 2000: ¥9,000,000 (Direct Cost: ¥9,000,000)
Keywordsfloating bone / distraction osteogenesis / elastic rubber / external fixation device / three-dimensional construction / 三次元構築 / 骨延長 / 顎顔面骨
Research Abstract

The aim of this investigation is to gain the stable occlusion and the good temporomandibular function using the floating bone methods. It leads to the three-dimensional construction of the mandibular bone in the target direction. The feature of this floating bone method is to use the elastic rubber instead of the conventional compulsory bone extension equipment. The stress is released and the direction of bone lengthening is easily controlled using elastic rubber. Positive occlusal movement was done to utilize the conformity of the bone. Therefore, the oral and maxillofacial distraction osteogenesis using the floating bone method developed the new three-dimensional mandibular reconstruction.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (27 results)

All Other

All Publications (27 results)

  • [Publications] 江口智明, 森良之, 高戸毅: "ハイドロキシアパタイト/ポリ乳酸複合体骨接合プレートシステムの口腔顎顔面外科領域での臨床経験"日本頭蓋顎顔面外科学会誌. 16巻3号. 41-49 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 井畑秀久, 米原啓之, 中塚貴志, 津山泰彦, 高戸毅: "幼若家兎を用いたCostochondral Graftの成長に関する実験的研究"日本形成外科学会会誌. 20巻11号. 648-659 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Y.Yonehara, T.Takato, T.Susami, Y.Mori: "Correction of Micrognathia Attributable to Ankylosis of the Temporomandibular Joint Using a Gradual Distraction Technique : Case Report"J. Oral Maxillofac Surg. 58巻. 1415-1418 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 高戸毅: "交通事故による顎顔面骨折の顎矯正力による治療"医研センタージャーナル研究助成特集号. 2月号. 8 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H.Hikiji, T.Takato, S.Matsumoto, Y.Mori: "Experimental Study of Reconstruction of the Temporomandibular Joint Using a Bone Transport Technique"J. Oral Maxillofac. Surg. 58巻. 1270-1276 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Y.Yonehara, T.Takato, S.Matsumoto, Y.Mori, T.Nakatsuka, H.Hikiji: "Correction of cleft lip nasal deformity in Orientals with a cantilevered iliac bone graft"Scand. J. Plast. Reconstr. Surg. Hand Surg. 34巻. 137-143 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 高戸毅: "頭頚部再建外科最近の進歩 第2版"骨延長による腫瘍切除後の下顎再建. 188-193 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Y. Yonehara, T. Takato, T. Susami and Y. Mori: "Correction of Micrognathia Attributable to Ankylosis of the Temporomandibular Joint Using a Gradual Distraction Technique : Case Report"J Oral Maxillofac Surg. 58. 1415-1418 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] D. Chikazu, M. Shindo, T. Iwasaka, M. Katagiri, N. Manabe, T. Takato, K. Nakamura, H. Kawaguchi: "A Novel Synthetic Triazolotriazepine Derivative JTT-606 Inhibits ZBone Resorption by Down-Regulation of Action and Production of Bone Resorptive Factors"J Bone Miner Res 2000. vol. 15(4). 674-682 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hikiji H, Shin WS, Koizumi T, Takato T, Susami T, Koizumi Y, Okai-Matsuo Y, Toyo-Oka T.: "Peroxynitrite production by TNA-alpha and IL-1beta : implication for suppression of osteo-blastic differentiation"Am J Physiol. 278. E1031-1037 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Hikiji, T. Takato, S. Matsumoto, Y. Mori: "Experimental Study of Reconstruction of the Temporomandibular Joint Using a Bone Transport Technique"J. Oral Maxillofac. Surg.. 58. 1270-1276 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yonehara Y, Takato T, Matsumoto S, Mori Y, Natsuka T, Hikiji H: "Correction of cleft lip nasal deformity in Orientals with a cantilevered iliac bone graft"Scand. J. Plast. Reconstr. Surg. Hand Surg. 34. 137-143 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] D. Chikazu, Y. Hakeda, K. Nemoto, A. Itabashi, T. Takato, M. Kumegawa, K. Nakamura and H. Kawaguchi: "Fibroblast growth factor-2 directly stimulates mature osteoclasts activity thought auto-phosphorylation of FGF receptor 1"J. Biol. Chem.. 275. 31444-31450 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M. Katagiri, Y. Hakeda, D. Chikazu, T. Ogasawara, T. Takato, M. Kumegawa, K. Nakamura, H. Kawaguchi: "Mechanism of Stimulation of Osteoclastic Bone Resorption through Gas6/Tyro 3, a Receptor Tyrosine Kinase Signaling, in Mouse Osteoclasts"The Journal of Biological Chemistry. 276 (10). 7376-7382 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 江口智明, 森良之, 高戸毅: "ハイドロキシアパタイト/ポリ乳酸複合体骨接合プレートシステムの口腔顎顔面外科領域での臨床経験"日本頭蓋顎顔面外科学会誌. 16巻3号. 41-49 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 井畑秀久, 米原啓之, 中塚貴志, 津山泰彦, 高戸毅: "幼若家兎を用いたCostochondral Graftの成長に関する実験的研究"日本形成外科学会会誌. 20巻11号. 648-659 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] Y.Yonehara, T.Takato, T.Susami, Y.Mori: "Correction of Micrognathia Attributable to Ankylosis of the Temporomandibular Joint Using a Gradual Distraction Technique : Case Report"J Oral Maxillofac Surg. 58巻. 1415-1418 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 高戸毅: "交通事故による顎顔面骨折の顎矯正力による治療"医研センタージャーナル 研究助成特集号. 2月号. 8 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] H.Hikiji, T.Takato, S.Matsumoto, Y.Mori: "Experimental Study of Reconstruction of the Temporomandibular Joint Using a Bone Transport Technique"J.Oral Maxillofac.Surg. 58巻. 1270-1276 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] Y.Yonehara, T.Takato, S.Matsumoto, Y.Mori, T.Nakatsuka, H.Hikiji: "Correction of cleft lip nasal deformity in Orientals with a cantilevered iliac bone graft"Scand.J.Plast.Reconstr.Surg.Hand Surg. 34巻. 137-143 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 高戸毅: "頭頚部再建外科最近の進歩 第2版(骨延長による腫瘍切除後の下顎再建)"克誠堂. 188-193 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Hikiji H: "Experimental Study of Reconstruction of the Temporomandibular Joint Using a Bone Transport Technique."J.Oral Maxillofac.Surg.. 58. 1270-1276 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Chikazu D.: "Fibroblast growth factor-2 directly stimulates mature osteoclasts activity through auto-phosphorylation of FGF receptor 1."J.Biol.Chem.. 275. 31444-31450 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Katagiri M.: "Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts."J.Biol.Chem.. (In press). (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Yonehara Y.: "Correction of cleft lip nasal deformity in Orientals with a cantilevered iliac bone graft."Scand.J.Plast.Reconstr.Surg.Hand Surg.. 34. 137-143 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hikiji H.: "Peroxynitrite production by TNF-alpha and IL-l beta : implication for suppression of osteoblastic differentiation."Am J Physiol.. 278. E1031-1037 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Chikazu D.: "A Novel Synthetic Triazolotriazepine Derivative JTT-606 Inhibits Bone Resorption by Down-Regulation of Action and Production of Bone Resorptive Factors."J.Bone Miner.Res.. 15(4). 674-682 (2000)

    • Related Report
      2000 Annual Research Report

URL: 

Published: 2000-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi