| Project/Area Number |
12554037
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
系統・分類
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| Research Institution | The Institute of Statistical Mathematics |
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Principal Investigator |
HASEGAWA Masami Institute of Statistical Mathematics, Department of Prediction Theory, Professor, 予測制御研究系, 教授 (60011657)
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| Co-Investigator(Kenkyū-buntansha) |
GOTOH Osamu Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Project leader, 生命情報, 主任研究員 (40142111)
SHIMODAIRA Hidetoshi Tokyo Institute of Technology, Lecturer, 情報理工学研究科, 講師 (00290867)
HASHIMOTO Tetsuo University of Tsukuba, Institute of Biological Sciences, Professor, 生物科学系, 教授 (50208451)
KISHINO Hirohisa University of Tokyo, Graduate School of Agriculture and Life Sciences, Professor, 農学生命科学研究科, 教授 (00141987)
足立 淳 理化学研究所, ゲノム科学総合研究センター, 研究員
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| Project Period (FY) |
2000 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥12,900,000 (Direct Cost: ¥12,900,000)
Fiscal Year 2002: ¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2001: ¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2000: ¥5,600,000 (Direct Cost: ¥5,600,000)
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| Keywords | molecular phylogenetics / model misspecification / phylogenetic inference / tree selection / divergence time / molecular clock / adaptive evolution / eutherian mammal / 多重比較 / 分子進化速度 / 階層モデル / 共進化 / 集団サイズ / 遺伝子構造予測 / SINE法 / SINE-flanking配列 / 分子時計 / 進化速度の変動 / 分岐時間推定 |
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| Research Abstract |
It is prerequisite to establish the phylogenetic relations among organises before studying biological evolution and biodiversity. We developed methods for inferring molecular phylogenies based on the likelihood approach and applied them tb various phylogenetic problems ;
(1) The effect of model misspecification in phylogenetic inference,
(2) Modelling in the phylogenetic inference ofmulti-gene data,
(3) Tests of phylogenetic tree selection,
(4) Methods for estimating divergence times without assuming a molecular clock,
(5) Detecting adaptive molecular evolution,
(6) Phylogenetic evolution of eutherian mammals
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