| Project/Area Number |
12557139
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Kyushu University |
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Principal Investigator |
NAKANO Hitoo Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Professor, 大学院・医学研究院, 教授 (40038766)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUSHIMA Kotaro Maternity and Perinatal Care Unit, Kyushu University Hospital, Research Associate, 医学部附属病院, 助手 (40304779)
SATOH Shoji Maternity and Perinatal Care Unit, Kyushu University Hospital, Assistant Professor, 医学部附属病院, 講師 (00225947)
FUKUSHIMA Shigehiro Division of Audio and Visual Communication, Graduate School of Design, Kyushu Institute of Design University, Professor, 大学院・芸術工学研究科, 教授 (60027927)
MOCHIZUKI Tsuyoshi ALOKA CO., LTD, Research Laboratory Senior Research Manager, 研究所, 主任研究員
堀本 直幹 九州大学, 大学院・医学研究院, 助手 (40243927)
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| Project Period (FY) |
2000 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥10,800,000 (Direct Cost: ¥10,800,000)
Fiscal Year 2002: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 2001: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2000: ¥6,100,000 (Direct Cost: ¥6,100,000)
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| Keywords | Fetus / Three dimensional Ultrasound / Fetal behavior |
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| Research Abstract |
The Volume-mode is a useful method to model three-dimensional ultrasound image, which is a relatively new modality with several potent advantages over conventional two-dimensional one, because it is based on accurate positional information. However, as this method requires long time to examine, it has been difficult to get real-time image. In this investigation, we developed the high-speed scanning probe and observed the fetal real-time movement.
The General Movement (GM), whose elegance and continuity is known to reflect central nervous system function in neonates, can be observed since 8-9 weeks of gestation in human fetuses. Hepper et al. reported that abnormal GM relates miscarriage in the first trimester. Visser et al. reported that fetal GM is similar to those of neonates. However, these observations were done using B-mode scan, thus it has been impossible to evaluate quantitatively.
We adopted this high-speed scanning probe to observe fetal GM and investigate on the relationship among the movements in each limbs. As a result, we found significant similarity between fetal GM and that of neonates in the relationship among the movements in each limbs. Although it was also expected to enable tissue characterization using this probe, it is still hard to detect fine structures in fetal hippocampus. It seemed to be required further technical improvement especially in hardware.
In summary, 1) we developed a new device which can observe fetal real-time movement, and found that 2) fetal GM in the first trimester is similar to that of neonates. 3) Fine tissue characterization in fetal brain is remained as a further assignment to be addressed.
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