• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

A study on stochastic models for the interaction between random drift and selection in population genetics

Research Project

Project/Area Number 12640139
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General mathematics (including Probability theory/Statistical mathematics)
Research InstitutionKyushu Dental College

Principal Investigator

IIZUKA Masaru  Kyushu Dental College, Faculty of Dentistry, Associate Professor, 歯学部, 助教授 (20202830)

Project Period (FY) 2000 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2002: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 2001: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2000: ¥600,000 (Direct Cost: ¥600,000)
Keywordspopulation genetics / stochastic processes / diffusion model / Wright-Fisher model / genealogy / fluctuation of population size / effective size of population / compensatory evolution / 集団遺伝子 / 環境変動 / 古人類学 / 弥生人 / ヘテロ接合度 / Kアレルモデル / 互助的中立突然変異 / 環境変動モデル / 自然淘汰 / 無限対立遺伝子モデル
Research Abstract

In this study, the effects of the stochastic fluctuation of population size on the effective size of population are investigated. For this end, three models (Wright-Fisher mode, diffusion mode, coalescent model) with the fluctuation of population size are formulated and their properties are studied. In the literature, it is said that the effective size is equal to the harmonic mean of fluctuating population size when population size is not constant. J. H. Gillespie (University of California at Davis) found, however, some examples where the effective size is not equal to the harmonic mean when the population size fluctuates stochastically. In the case where population size fluctuates stochastically, it is important to know how the effective size is related to the harmonic mean and the arithmetic mean and the condition under which the effective size is equal to the harmonic mean. It is shown that the effective size is larger than the harmonic mean but it is smaller than the arithmetic mean for the diffusion model and the coalescent model. For the Wright-Fisher model, the effective size is larger (resp. smaller) than the harmonic mean if the fluctuation of population size is positively (resp. negatively) autocorrelated. The effective size is equal to the harmonic mean if and only if the fluctuation of population size is independent from generation to generation. The conditions on the parameters of the models under which the effective size is asymptotically equal to the harmonic mean or the arithmetic mean are obtained.

Report

(4 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • Research Products

    (19 results)

All Other

All Publications (19 results)

  • [Publications] Masaru Iizuka: "Compesatory neutral mutation model with dominance"京都大学数理解析研究所講究録. 1193. 54-63 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka: "The effective size of fluctuating populations"Theoretical Population Biology. 59. 281-286 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 飯塚 勝: "集団遺伝学と確率過程"九州歯科大学一般教育研究紀要. 7. 1-25 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka: "A neutral model with fluctuating population size and its effective size"Genetics. 161. 381-388 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka: "A population genetic study on the transition from Jomon people to Yayoi people"Genes & Genetic Systems. 77. 287-300 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masashi Yokota: "Genetic drift in a hatchery and the maintenance of genetic diversity in hatchery-wild systems"Fisheries Science. 69. 101-109 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka and Tomoyuki Kado: "Compensatory neutral mutation model with dominance"RIMS Kokyuroku (Kyoto University). 1193. 54-63 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka: "The effective size of fluctuating populations"Theoretical Population Biology. 59. 281-286 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka: "Population Genetics and Stochastic Processes"Bulletin of Kyushu Dental College (Liberal Arts and Sciences). 7. 1-25 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka, Hidenori Tachida and Hirotsugu Matsuda: "A neutral model with fluctuating population size and its effective size"Genetics. 161. 381-388 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka and Takahiro Nakahashi: "A population genetic study on the transition from Jomon people to Yayoi people"Genes & Genetic Systems. 77. 287-300 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masashi Yokota, Yasushi Harada and Masaru Iizuka: "Genetic drift in a hatchery and the maintenance of genetic diversity in hatchery-wild systems"Fisheries Science. 69. 101-109 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Masaru Iizuka: "A neutral model with fluctuating population site and its effective size"Genetics. 161. 381-388 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Masaru Iizuka: "A population genetic study on the transition from Jomon people to Yayoi people"Genes & Genetic Systems. 77. 287-300 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Masashi Yokota: "Genetic drift in a hatchery, and the maintenance of genetic diversity in hatchery-wild system"Fisheries Science. 69. 101-109 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Masaru Iizuka: "The Effective Size of Fluctuating Populations"Theoretical Population Biology. 59. 281-286 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 飯塚 勝: "集団遺伝学と確率過程"九州歯科大学一般教育研究紀要. (印刷中).

    • Related Report
      2001 Annual Research Report
  • [Publications] 飯塚勝: "Compensatory Neutral Mutation Model with Dominance"京都大学数理解析研究所講究録. (掲載予定).

    • Related Report
      2000 Annual Research Report
  • [Publications] 飯塚勝: "Infinite Allele Model with Fluctuating Population Size and the Effective Size of Population"京都大学数理解析研究所講究録. (掲載予定).

    • Related Report
      2000 Annual Research Report

URL: 

Published: 2000-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi