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Efficient Mixing or Liquid/Liquid-Extraction in Zigzag-Shaped Microchannel

Research Project

Project/Area Number 12640578
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 分離・精製・検出法
Research InstitutionThe University of Tokyo

Principal Investigator

KIM Haeng-boo  School of Enginnering, The University of Tokyo Assoc. Prof, 工学部・附属総合試験所, 助教授 (40186367)

Co-Investigator(Kenkyū-buntansha) HIBARA Akihide  School of Enginnering, The University of Tokyo Res. Assc, 工学部・附属総合試験所, 助手 (30312995)
KITAMORI Takehiko  School of Enginnering, The University of Tokyo Prof, 大学院・工学系研究科, 教授 (60214821)
Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2001: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2000: ¥2,200,000 (Direct Cost: ¥2,200,000)
Keywordsmicrochannel / shape effect / mixing / liquid / liquid extraction / microspectrosco / flow profile
Research Abstract

The Flow characteristics in a microchannel, operated by pressure-driven flow, are described by a low Reynolds-number flow : laminar flow. In laminar flow, the flow line runs parallel with the cannel-wall, so that the inertial effects on molecular motions and the turbulent mixing of solution do not occur. Owing to such flow characteristics, even when two solutions are introduced separately into a microchannel chip, the two folutions in the single channel can flow witout any mutual mixing. On the other hand, molecular diffusion along the channel-width direction take place, thus, solute molecules dissolved in one solution phase can cdistributed to the other phase : diffusional mixing, while the efficiency is insufficient. It is supposed that the flow characteristics might be influenced by the shape of the channel. In this study, therfore, shape effects of microchannel on a mixing of two miscible solutions and liquid/liquid extraction of two immiscible solutions were explored by usin spatially-resolved microspectroscopy. Polymer-substrate chips having a flat-side-walled channel (symmetrical and unsymmetrical zigzag side walled) were fabricated. In the unsymmetrical zigzag-side walled channel, the interface was sinusoidal reflecting on the shape, while it was flat in flat-or symmetrical-side-walled channel. Since the interface shape affects on contact time of the two solutions, the unsymmetrical zigzag-side walled channel syowed the most efficient mixing or extraction efficiency. In the symmetrical zigzag channel. the efficiency become worse than in flat-shape channel because of retention flow. These results were also supported fro, flow analysis by mathematical calculation.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] Osamu Kogi: "Auto-Oscillated Vibration of Single Micrometer-Sized Oil Droplets in Aqueous Surfactant Solution"Langmuir. 24. 7456-7458 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yuki Tanaka: "Acceleration of an Enzymatic Reaction in a Microchip"Anal. Sci.. 17. 809-810 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Satoshi Habuchi: "Water Structure in Ion-Exchange Resin Particles : Solvation Dynamics of Nile Blue A"Anal. Chem.. 73. 366-372 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kohsei Ueno: "Fabrication and Characteristic Responses of Integrated Microelectrodes in Polymer Channel Chip"Chem. Lett.. (8). 858-859 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Osamu Kogi: "Microinjection-Microspectroscopy of Single Oil Droplets in Water : An Application to Liquid/Liquid Extraction under Solution-Flow Conditions"Anal. Chim. Acta. 418. 129-135 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Haeng-Boo Kim: "A Spatially-Resolved Fluorescence Spectroscopic Study on Liquid/Liquid Extraction-Processes in Polymer Microchannels"Anal. Sci.. 16. 871-876 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] O. Kogi: "Auto-Pscillated Vibration of Single Micrometer-Sized Oil Droplets in Aqueous Surfactant Solution"Langmuir. 24 (17). 7456-7458 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Y. Tanaka: "Acceleration of an Enzymatic Reaction in a Microchip"Anal. Sci. 17 (7). 809-810 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Habuchi: "Water Structure in Ion -Exchange Resin Particles : Sovation Dynamics of Nile Bule A"Anal. Chem. 73 (2). 366-372 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] K. Ueno: "Fabrication and Characteristic Responses of Integrated Microelectrodes in Polymer Channel Chip"Chem. Lett. (8). 858-859 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] O. Kogi: "Microinjection-Microspectroscopy of Single Oil Droplets in Water. An Application to Liquid/Liquid Extraction under Solution-Flow Conditions"Anal. Chim. Acta. 418. 129-135 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H.-B. Kim: "A Spatially -Resolved Fluorescence Spectroscopic Study on Liquid/Liquid Extraction Processes in Polymer Microchannels"Anal. Sc i. 16 (8). 871-876 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 喜多村 昇: "ポリマーマイクロチャンネルチップの創製とその化学的応用"電気学会誌E(センサ・マイクロマシン). 121E(4). 169-174 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Osamu Kogi: "Auto-Oscillated Vibration of a Micrometer-Sized Oil-Droplet in Aqueous Surfactant Solution"Langmuir. 24(17). 7456-7458 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Haeng-Boo.Kim: "Microinjection-Microspectroscopy of Single Oil Droplets in Water : An Application to Liquis/Liquid Extraction under Solution-Flow Conditions."Anal.Chim.Acta..

    • Related Report
      2000 Annual Research Report
  • [Publications] Kousei Ueno: "Fabrication and Characteristic Responses of Integrated Microelectrodes in Polymer Channel Chip."Chem.Lett.. ・8. 858-859 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kiyoshi Sato: "Molecular Transport between Two Phases in a Microchannel"Anal.Sci.. 16・5. 455-456 (2000)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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