Transfer of egg probeins into breast milk
| Project/Area Number |
12660125
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
食品科学・栄養科学
|
|---|
| Research Institution | Junior College of Kyoto Women's University |
|---|
Principal Investigator |
NARITA Hiroshi Dept. of Life Science, Junior College of Kyoto Women's University, Professor, 短期大学部・生活科学科, 教授 (30155999)
|
|---|
| Project Period (FY) |
2000 – 2001
|
| Project Status |
Completed (Fiscal Year 2001)
|
| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2001: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2000: ¥2,200,000 (Direct Cost: ¥2,200,000)
|
|---|
| Keywords | food allergy / allergen / egg / ovomucoid / breast milk / monoclonal antibody / immune complex / secretory IgA |
|---|
| Research Abstract |
On gel-filtration, the major food allergen, ovomucoid (28 kDa) in human breast milk was eluted only at the fractions corresponding to a molecular weight of about 450 kDa. Almost same elution profile as that for ovomucoid was obtained for its immune complex with sIgA. Similar results, suggesting the occurrence of food allergens as immune complexes with sIgAs have been also observed for other food allergens in breast milk. Relationship between the presence of allergens in mother's milk and allergic symptoms of their babies should be discussed hereafter in consideration of not only the level but also the molecular feature of allergens.
|
Report
(3 results)
Research Products
(6 results)
