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Effects of the use of cloning technique on breeding structure of domestic animal populations

Research Project

Project/Area Number 12660260
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied animal science
Research InstitutionKyoto Sangyou University

Principal Investigator

NOMURA Tetsuro  Kyoto Sangyou University, Faculty of Engineering, Professor, 工学部, 教授 (50189437)

Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2001: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2000: ¥1,000,000 (Direct Cost: ¥1,000,000)
KeywordsCloning / Breeding structure / Statistical genetics / Beef cattle / Genetic diversity / Effective population size / Inbreeding / クローン / 家畜育種 / 遺伝的多様体 / 遺伝的改良
Research Abstract

The efficiencies of the use of cloning technique were evaluated under three typical situations of beef cattle breeding, by means of statistical genetics methods.
1. Use of clones as commercial stock
The intuitive merit of the use of clones as commercial stock is the increase in uniformity of final products. This expectation was evaluated in terms of the coefficient of correlation and the standard error of difference between clones. It was shown that clones would be somewhat more uniform than other pairs of relatives, but would not be as uniform as most people would expect.
2. Clone testing
The efficiency of clone testing as an alternative to the conventional progeny testing was evaluated in terms of the accuracy of selection. It was found that there are situations under which the conventional progeny testing is preferable to the clone testing, depending on the amount of dominance variation and the number of tested animals.
3. Use of cloned sires
(1) Probability of finding a "super" sire
A "super" sire is defined as a bull who has a prominent performance enough to justify to make his clones. Using a deterministic model, the probability that we can find a "super" sire was calculated. The results showed that in a population with a moderate genetic gain, the probability would be quite low.
(2) Effect of the use of cloned sires on genetic diversity
Applying a stochastic simulation technique to pedigree records of Japanese Black cattle, the effect of the use of cloned sires on genetic diversity was examined. In a population in which the donor sire had been intensively used, the use of his clones would lead to a drastic reduction of genetic diversity.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (22 results)

All Other

All Publications (22 results)

  • [Publications] 野村哲郎: "クローン技術と和牛の育種"(発表予定). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tetsuro Nomura: "Inbreeding and effective population size of Japanese Black cattle"Journal of Animal Science. 78. 366-370 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Takeshi Honda: "Genetic diversity of a closed population of Japanese Black cattle in Hyogo prefecture"Animal Science Journal. 72. 378-385 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tetsuro Nomura: "Comparison of selection schemes for achieving desired genetic gains in closed broiler lines"Animal Science Journal. 72. 386-394 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Takeshi Honda: "Gene dropping analysis of founder contributions in a closed Japanese Black cattle population"Animal Science Journal. (印刷中). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 野村哲郎: "ハプロタイプが不確定な集団における配偶子関係行列の近似計算"計量生物学. 21. 65-76 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tetsuro Nomura: "The doning technique and breeding of Wagyu"(in preparation).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tetsuro Nomura, Takeshi Honda and Fumio Mukai: "Inbreeding and effective population size of Japanese Black cattle"Journal of Animal Science. 78. 366-370 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Takeshi Honda, Tetsuro Nomura, Moriyuki Fukushima and Fumio Mukai: "Genetic diversity of a closed population of Japanese Black cattle in Hyogo prefecture"Animal Science Journal. 72. 378-385 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tetsuro Nomura, Fumio Mukai and Aya Yamamoto: "Comparison of selection schemes for achieving desired genetic gains in closed broiler lines"Animal Science Journal. 72. 386-385 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Takeshi Honda, Tetsuro Nomura, Moriyuki Fukushima and Fumio Mukai: "Gene dropping analysis of founder contributions in a closed Japanese Black cattle population"Animal Science Journal. 73 (in press). (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tetsuro Nomura: "An approximation of gametic relationship matrix in a population with uncertainty of haplotypes"Japanese Journal of Biometrics. 21. 65-76 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 野村哲郎: "クローン技術と和牛の育種"(発表予定). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Tetsuro Nomura: "Inbreeding and effective population size ofJapanese Black cattle"Journal of Animal Science. 78. 366-370 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Takeshi Honda: "Genetic diversity of a closed population of Japanese Black cattle in Hyogo prefecture"Animal Science Journal. 72. 378-385 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Tetsuro Nomura: "Comparison of selection schemes for achieving desired genetic gains in closed broiler lines"Animal Science Journal. 72. 386-394 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Takeshi Honda: "Gene dropping analysis of founder contributions in a closed Japanese Black cattle population"Animal Science Journal. (印刷中). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 野村哲郎: "ハプロタイプが不確定な集団における配偶子関係行列の近似計算"計量生物学. 21. 65-76 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 野村哲郎: "ハプロタイプが不確定な集団における配偶子関係行列の近似計算"計量生物学. 21,1. 65-76 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Tetsuro Nomura: "Effective Population Size under Marker-Assisted Selection"Japanese Journal of Biometrics. 21,1. 1-12 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 野村哲郎: "黒毛和種の集団構造に関する遺伝学的分析"動物遺伝育種研究. 28,1. 59-67 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Tetsuro Nomura: "Inbreeding and effective population size of Japanese Black Cattle"Journal of Animal Science. 79,2. 366-370 (2001)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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