| Project/Area Number |
12670873
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Shimane Medical University |
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Principal Investigator |
UCHIDA Nobue (2001) Shimane Medical University, Department of Radiology, Associate Professor, 医学部, 助教授 (80304260)
元原 智文 (2000) 島根医科大学, 医学部, 助手 (90322221)
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| Co-Investigator(Kenkyū-buntansha) |
KATO Hirokazu Okayama University, School of Medicine, Department of Health Science, Professor, 医学部, 教授 (60127511)
YOSHIKAWA Takeshi Shimane Medical University, Department of Radiology, Instructor, 医学部, 助手 (40332788)
KITAGAKI Hajime Shimane Medical University, Department of Radiology, Professor, 医学部, 教授 (10234238)
SUGIMURA Kazuro Kobe University, School of Medicine, Department of Radiology, Professor, 医学部, 教授 (00136384)
KURODA Kagayaki Tokai University, Faculty of Engineering, Professor, 工学部, 教授 (70205243)
内田 伸恵 島根医科大学, 医学部, 助教授 (80304260)
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| Project Period (FY) |
2000 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2001: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2000: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Keywords | Hyperthermia / Interstitial heating / Ultrasound heating / Remote After Loading System (RALS) / MRI / Proton chemical shift / Temperature measurement / Remote After Loading System(RALS) |
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| Research Abstract |
1. Development of agar phantom suitable for Magnetic Resonance Imaging : For the purpose of three-dimensional temperature measurement by MRI, it was necessary to develop a new phantom compatible to MRI and interstitial heating. For this purpose, nickel sulfate was added to a muscle-equivalent agar phantom. The feasibility of this new phantom was evaluated using a MR temperature measuring technique previously developed and supported by MEXT Grant-in-Aid (09557070).
2. Development of gate circuit : To operate MR equipment and ultrasound generator simultaneously, a mutual gate circuit of the signal is required. The basic design of the gate circuit was developed, and the prototype of the gate circuit was produced.
3. Development of the three-dimensional temperature distribution measurement software : As a basic study for the high-speed temperature measurement software development, the monitoring interval and the stability of the measurement result were examined. There was a stabilizing tendency with the longer measurement intervals. The instability of the magnetic field was suspected to affect this result. For the shortening of the measurement interval and for three-dimensional temperature monitoring, it is necessary to develop a temperature monitoring sequence which is not significantly affected by magnetic field fluctuation.
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