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Development of phase sensitive radiography for human imaging by means of synchrotron radiation

Research Project

Project/Area Number 12670895
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionIBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES

Principal Investigator

MORI Koichi  IBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES ・ DEPT. OF RADIOLOGICAL SCIENCES, PROFESSOR, 保健医療学部, 教授 (90274977)

Co-Investigator(Kenkyū-buntansha) HYODO Kazuyuki  HIGH ENERGY ACCELERATOR RESEARCH ORGANIZATION INSTITUTE OF MATERIAL STRUCTURE SCIENCES, ASSISTANT, 物質構造科学研究所, 助手 (60201729)
SATO Hitoshi  IBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES ・ DEPT. OF RADIOLOGICAL SCIENCES, ASSISTANT, 保健医療学部, 助手 (90285057)
SHIKANO Noto  IBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES ・ DEPT. OF RADIOLOGICAL SCIENCES, ASSISTANT, 保健医療学部, 助手 (80295435)
ANDO Masami  HIGH ENERGY ACCELERATOR RESEARCH ORGANIZATION INSTITUTE OF MATERIAL STRUCTURE SCIENCES, PROFESSOR, 物質構造科学研究所, 教授 (30013501)
Project Period (FY) 2000 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2002: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2001: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2000: ¥2,400,000 (Direct Cost: ¥2,400,000)
KeywordsSynchrotron Radiation / Radiography / Refraction Contrast / Wooden Foreign Body / Small Fracture / Calcification / Spatial Coherence / Reduction of Exposure Dose / 被曝線量の軽減 / 位相コントラスト / 骨画像 / フレネル回折 / 干渉性
Research Abstract

Refraction contrast imaging of the fine structures of the ribs of a pig and a specimen of human osteosarcoma utilizing the spatial coherence of synchrotron X-rays was successfully performed with an incident X-ray energy of 30 keV at KEK.PF and SPring-8. The image contrast appearing at the periphery of trabecular bone, small calcification and small fractures is caused by the phase shift of the X-rays at the boundary of these objects that have different X-ray refractive indices. The image was recorded on mammography film without an intensifying screen. Comparison of the image contrast using different sample-to-film distances, Z, such as Z=5 m and Z=0 m, showed that the former images were always more informative, i.e. better in resolution and /or image contrast when imaging of trabecular bone, bone marrow and small fractures in compact bone, and for imaging of cartilage.
Refraction contrast imaging of a pig head with penetration of wooden foreign body in his oral cavity utilizing the spatial coherence of synchrotron X-rays was successfully performed with an incident X-ray energy of 35 keV at BL20B2 of SPring-8. The image was recorded on mammography film with an intensifying screen. Comparison of the image contrast using different sample-to-film distances such as Z=5 m and Z=0 m, showed that the former images were always more informative, i.e. the wooden foreign body could be detected only by the refraction contrast imaging.
Radiography using synchrotron X-rays for phase objects should be a powerful tool for diagnosis in orthopedics and wooden foreign body imaging.

Report

(4 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • Research Products

    (28 results)

All Other

All Publications (28 results)

  • [Publications] K.Mori, H.Sato, et al.: "Development of Phase Contrast Radiography for Bone imaging Using Synchrotron Radiation"Analytical Sciences. 17. i1427-i1430 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K.Mori, et al.: "Application of Synchrotron X-ray Imaging to Phase Objects in Orthopedics"J.Synchrotron Rad.. 9・5. 143-147 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K.Mori, et al.: "First Observation of a Wooden Foreign Body in Soft Palate by Means of Synchrotron X-ray Refraction Contrast"Jpn.J.Appl.Phys.. 41・8. 5490-5491 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] H.Sato, K.Mori, et al.: "Phase Contrast Imaging for Mammography Using Synchrotron X-rays"M.J.Ibaraki P.H.. 20・2. 73-82 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 森 浩一, 関根紀夫, 佐藤斉 他: "放射光X線を用いた屈折コントラストによる骨画像"放射光X線を用いた屈折コントラストによる骨画像. 22・1. 13-20 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K.Mori, et al.: "Development of Radiological Osteometry by Means of Synchrotron X-ray Phase Contrast"SPring-8 User Experiment Report. 9(2002A). 125 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] "Development of a Novel Bone Radiography by Means of Synchrotron X-ray Phase Contrast"Mediral Imaging Technology. 18-4. 441-442 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koichi Mori: "Development of Phase Contrast Radiography for Bone Imaging Using Synchrotron Radiation"Analytical Sciences. 17. i1427-i1430 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koichi Mori: "Application of Synchrotron X-ray Imaging to Phase Objects in Orthopedics"J.Synchrotron Rad.. 9-5. 143-147 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koichi Mori: "First Observation of a Wooden Foreign Body in Soft Palate by Means of Synchrotron X-ray Refraction Contrast"Jpn.J.Appl.Phys.. 41-8. 5490-5491 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Hitoshi Sato: "Phase Contrast Imaging for Mammography Using Synchrotron X-rays"M.J.Ibaraki P.H.. 20-2. 73-82 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koichi Mori: "Refraction-contrast Imaging Using Synchrotron Radiation"Jpn.J.Med.Phys.. 22-1. 13-20 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koichi Mori: "Development of Radiological Osteometry by Means of Synchrotron X-ray Phase Contrast"SPring-8 User Experiment Report. 9. 125 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K.Mori, H.Sato, et al.: "Development of Phase Contrast Radiography for Bone Imaging Using Synchrotron Radiation"Analytical Sciences. 18・4. i1427-i1430 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] K.Mori, et al.: "Application of Synchrotron X-ray Imaging to Phase Objects in Orthopedics"J. Synchrotron Rad.. 9・5. 143-147 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] K.Mori, et al.: "First Observation of a Wooden Foreign Body in Soft Palate by Means of Synchrotron X-ray Refraction Contrast"Jpn. J. Appl. Phys.. 41・8. 5490-5491 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] H.Sato, K.Mori, et al.: "Phase Contrast Imaging for Mammography Using Synchrotron X-rays"M. J. Ibaraki P. H.. 20・2. 73-82 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 森 浩一, 関根紀夫, 佐藤斉 他: "放射光X線を用いた屈折コントラストによる骨画像"医学物理. 22・1. 13-20 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] K.Mori, et al.: "Development of Radiological Osteometry by Means of Synchrotron X-ray Phase Contrast"SPring-8 User Experiment Report. 9(2002A). 125 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] K.Mori, et al.: "Development of Phase Contrast Radiography and its Application to the Diagnosis of Orthopedic Diseases"Photon Factory Activity Report. 18・part A. 45-46 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] K.Mori, et al.: "Development of Human Imaging on Orthopedics by means of Synchrotron X-ray Phase Contrast"SPring-8 User Experiment Report. 7・2001A. 110 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] K.Mori, et al.: "Development of Phase contrast radiography for Bone Imaging Using Synchrotron Radiation"Analytical Sciences. (特別号)(未定(編集中)). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] K.Mori,N.Shikano,K.Hyodo,M.Ando et al.: "Development of a novel bone radiography by means of x-ray phase contrast"Spring-8 User Experiment Report. 5・2000A. 178 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 森浩一,佐藤斉,鹿野直人,兵藤一行,安藤正海 他: "放射光を用いたX線位相敏感画像法の開発と整形外科領域への適用"Photon Factory News. 18・2. 21-24 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 森浩一,鹿野直人,佐藤斉,兵藤一行,安藤正海 他: "放射光X線位相コントラストによる骨折線描写のための新しい撮影法"茨城県立病院医学雑誌. 18・1. 33-37 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] K.Mori,N.Shikano,H.Soto,K.Hyodo,M.Ando et al.: "Development of a novel bone radiography by means of synchrotron x-ray phase contrast"Medical imaging technology. 18・4. 441-442 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 森浩一,鹿野直人,佐藤斉,兵藤一行,安藤正海 他: "X線位相コントラスト法による骨画像と放射光X線撮影システム"コニカXレイ写真研究. 51・3. 17-21 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] K.Mori,N.Shikano,H.Soto,K.Hyodo,M.Ando et al.: "Development of a novel radiography for visualization of fracture line by means of synchrotron x-ray phase contrast"Book of abstracts of the 7 th international conference on synchrotron radiation instrumentation. Pos2-219 (2000)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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