| Project/Area Number |
12671153
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | NIPPON MEDICAL SCHOOL (2002)
Kyoto University (2000-2001) |
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Principal Investigator |
MIYAMOTO Masaaki Nippon Medical School, First Dept. of Internal Medical, Associate Professor, 医学部, 助教授 (50229895)
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| Co-Investigator(Kenkyū-buntansha) |
高橋 玲 京都大学, 医学研究所, 助教授 (60144565)
岩田 博夫 京都大学, 再生医科学研究所, 教授 (30160120)
井上 一知 京都大学, 再生医科学研究所, 教授 (90168435)
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| Project Period (FY) |
2000 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,900,000)
Fiscal Year 2002: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2001: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2000: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Keywords | islets / isolation procedure / cry a preservation of islets / islet transplantation / two-step isolation procedure of islets / islets / 膵島凍結保有法 / バイオ人工膵 / 異種移植 / ブタ膵島幹細胞 / 膵島皮下移植 / 膵島筋肉内移植 / 異種膵島移植 / 膵幹細胞 / 細胞移植 / 糖尿病 / PGP9.5 |
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| Research Abstract |
(1) Development of isolation procedure of pancreatic islets for large animals. We developed 2-step automated isolation procedure of pancreatic islets for miniature swine and dogs.
This procedure is possible to use human pancreatic islets for human islets transplantation.
(2) Development of automated cry a preservation procedure for pancreatic islets. We developed cry a preservation procedure employing a freezer bag for pancreatic islets using a newly developed cry a protectant.
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