Project/Area Number |
12671248
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Digestive surgery
|
Research Institution | Kyoto Prefectural University of Medicine |
Principal Investigator |
KITAMURA Kazuya Kyoto Prefectural University of Medicine, Surgery, Assistant Professor, 医学部, 助手 (10224966)
|
Project Period (FY) |
2000 – 2002
|
Project Status |
Completed (Fiscal Year 2002)
|
Budget Amount *help |
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2002: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2001: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2000: ¥1,800,000 (Direct Cost: ¥1,800,000)
|
Keywords | Gastric cancer / Surgery / Monoclonal antibody / モノクローナル抗体 |
Research Abstract |
I have investigated in a development of a novel monoclonal antibody conjugated with Polyethylene glycol (PEG) and applied in a navigation surgery using the radiolabeled PEG-monoclonal antibody. In animal experiment using rabbit, the PEG-monoclonal antibody accumulated in various regional lymph nodes surrounding the stomach. This result indicates that PEG-monoclonal antibody can be promising for navigation surgery for gastric cancer
|