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EVALUATION OF BLOOD FLOW IN THE BONE BY DYNAMIC MRI

Research Project

Project/Area Number 12671390
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionASAHIKAWA MEDICAL COLLEGE

Principal Investigator

GOTOH Eiji  ASAHIKAWA MEDICAL COLLEGE, DEPT. OF ORTHOPAEDICS, ASSISTANT PROFESSOR, 医学部, 講師 (50142807)

Co-Investigator(Kenkyū-buntansha) MATSUNO Takeo  ASAHIKAWA MEDICAL COLLEGE, DEPT. OF ORTHOPAEDICS, PROFESSOR, 医学部, 教授 (10165847)
TOGIYA Satoshi  ASAHIKAWA MEDICAL COLLEGE, DEPT. OF ORTHOPAEDICS, RESEARCH ASSISTANT, 医学部, 助手 (80322907)
Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2001: ¥900,000 (Direct Cost: ¥900,000)
KeywordsMRI / BONE MARROW / FEMORAL HEAD / BLOOD FLOW / NECROSIS / FEMORAL NECK FRACTURE / 犬
Research Abstract

We evaluated the blood flow in the bone by using dynamic MRI in experimental study.
Experiment 1: We made a femoral neck fracture surgically in dogs and analyzed the changes of signal intensity in the femoral head by dynamic MRI. Although the significant decrease of signal intensity was observed immediately after injection of Gd in the control side, no change of signal intensity was detected in the experimental side. In the prostata which has rich blood flow, same pattern of changes of signal intensity was observed. This phenomenon was thought to be so called suceptibility effects which mean the presence of blood flow in MRI findings of brain. From these results, acute decrease of signal intensity after Gd injection thought to be the proof of blood flow in the bone.
Experiment 2: We made dynamic MRI in normal adults without disease of hip joint. The signal intensity decreased in 20 〜 30 seconds after injection of Gd. This pattern of changes of intensity was same as that of animal experiment. We indicated the possibility of measurement of blood flow in the bone by using MRI in clical study.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (19 results)

All Other

All Publications (19 results)

  • [Publications] E.Gotoh, M.Tsuji, T.Matsuno, M.Ando: "Acetabular development after reduction in developmental dislocation of the hip"Clinical Orthopaedics and Related Research. 378. 174-182 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 寺西 正, 後藤英司, 稲尾茂則, 研谷 智, 高桑昌幸, 松野丈夫: "大腿骨頭回転骨切り術における新しい内固定金属-Adjustable Angle Hip System-"Hip Joint. 26. 86-88 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 高桑昌幸, 後藤英司, 稲尾茂則, 研谷 智, 寺西 正, 松野丈夫: "Triple osteotomyの術後長期成績"Hip Joint. 26. 309-312 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 寺西 正, 後藤英司, 稲尾茂則, 松野丈夫, 安藤御史, 岡本哲軌: "Charnley型人工股関節置換術-15年以上経過例の成績-"骨・関節・靭帯. 13(1). 35-39 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 前田龍智, 後藤英司, 寺西 正, 松野丈夫: "大腿骨頭血流評価はdynamic MRIを用いて本当に可能か"別冊整形外科. 38. 19-23 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 後藤英司, 寺西 正: "Charnly式人工股関節置換術の術後20年におけるX線成績"整形外科. 53巻3号. 249-254 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] E. GOTOH, M. TSUJI, T. MATSUNO, M. ANDO: "Acetabular development after reduction in developmental dislocation of the hip."Clinical Orthopaedics and Related Research. 378. 174-182 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T. TERANISHI, E. GOTOH, S. INAO: "New fixation device for trans trochanteric rotation osteotomy for osteonecrosis of the femoral head - Adjustable Angle Hip System -"Hip Joint. 26. 86-88 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M. TAKAKUWA, E. GOTOH, S. INAO: "Long term results of triple osteotomy for dysplastic hip"Hip Joint. 26. 309-312 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T. TERANISHI, E. GOTOH, S. INAO: "Clinical results of Charnley Low Friction Arthroplasty at 15 years after surgery"Bone Joint and Tendon. 1335-1339 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T. MAAEDA, E. GOTOH, T. TERANISHI, T. MATSUNO: "Can we evluate the blood flow in the bone by using dynamic MRI?"SEIKEIGEKA. 38. 19-23 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] E. GOTOH, T.TERANISHI, T. MATSUNO, M. ANDO: "Radiologic results of Charnley Low Friction Arthroplasty at 20 years after surgery"SEIKEIGEKA. 53. 249-254 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] E.Gotoh, M.Tsuji, T.Matsuno, M.Ando: "Acetabular development after reduction in developmental dislocation of the hip"Clinical Orthopaedics and Related Research. 378. 174-182 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 寺西 正, 後藤英司, 稲尾茂則, 研谷 智, 高桑昌幸, 松野丈夫: "大腿骨頭回転骨切り術における新しい内固定金属-Adjustable Angle Hip System-"Hip Joint. 26. 86-88 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 高桑昌幸, 後藤英司, 稲尾茂則, 研谷 智, 寺西 正, 松野丈夫: "Triple osteotomyの術後長期成績"Hip Joint. 26. 309-312 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 寺西 正, 後藤英司, 稲尾茂則, 松野丈夫, 安藤御史, 岡本哲軌: "Charnley型人工股関節置換術-15年以上経過例の成績-"骨・関節・靭帯. 13(1). 35-39 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 前田 龍智, 後藤 英司, 寺西 正, 松野丈夫: "大腿骨頭血流評価はdynamic MRIを用いて本当に可能か"別冊整形外科. 38. 19-23 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 後藤 英司, 寺西 正: "Chanly式人工股関節置換術の術後20年におけるX線成績"整形外科. 53巻3号. 249-254 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 前田龍智 他: "大腿骨頭血流評価はdynamic MRIを用いて本当に可能か"別冊整形外科. No.38. 19-23 (2000)

    • Related Report
      2000 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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