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Functional and morphological analysis of the striatal region which relates to control of jaw-, tongue-, and facial movements in the rat

Research Project

Project/Area Number 12671811
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Functional basic dentistry
Research InstitutionKyushu Dental College

Principal Investigator

AMANO Niichiro  Faculty of Dentistry, professor, 歯学部, 教授 (60076015)

Co-Investigator(Kenkyū-buntansha) SATODA Takahiro  Hiroshima University, Graduate School of Biomedical Sciences, Assistant professor, 大学院・医歯薬学総合研究科, 助教授 (80170801)
Project Period (FY) 2000 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2002: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 2001: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 2000: ¥2,900,000 (Direct Cost: ¥2,900,000)
KeywordsBasal ganglia / Striatum / Cerebral cortex / Jaw movement / Retrograde labeling / Microstimulation / Electromyograph / Rat / Cerebral cortex / 線条体 / ラット / 開口筋 / 電気微小刺激 / 化学微小刺激 / カイニン酸 / 舌突出筋
Research Abstract

We found that electrical microstimulation of the jaw region of the rat striatum (SJR) activates the jaw-opening and tongue-protruder muscles, but not the jaw-closing, tongue-retractor, or facial muscles (Neurosci. Lett. 253 : 79-82, 1998 ; Brain Res., 893 : 282-286, 2001). Such effect can be induced even after removal of the cerebral cortex, but not after destruction of striatal neurons by injecting kainic acid into the SJR. Therefore, the effect of the stimulation of the SJR is considered to be produced by the stimulation of striatal neurons in the SJR ; it is not the effect of stimulation of corticofugal fibers through the SJR. In the present study, we examined the sites of origin of cortico-SJR fibers by the retrograde labeling. The SJR, identified by electrical microstimulation, was injected electrophoretically with cholera toxin B subunit. Retrogradely labeled neuronal cell bodies were detected mainly in the following regions : 1) Cerebral cortex : frontal cortical regions, includ … More ing the motor and somatosensory areas, and insural cortical regions. Labeled cell bodies were distributed to layers II, III, V and VI of these cerebral cortical regions ; 2) Thalamus : central medial nucleus, paracentral nucleus, parafascicular nucleus ; 3) Amygdala : basolateral nucleus ; 4) Substantia nigra pars compacta ; 5) Dorsal raphe nucleus. Termial labeling was also seen in the globus pallidus, entopeduncular nucleus and substantia nigra pars reticulata. In the cerebral cortex ipsitateral to the injection, there existed two foci of retrograde labeling : One focus was centered on the lateral part of the sensorimotor area, while the other on the insular cortical area around the middle cerebral artery. These foci appeared to correspond to the reported two cortical areas, where two different types of rhythmical jaw movements were induced by repetitive electrical stimulation (Jap. J. Oral Biol., 32 : 57-68, 1990). It is also well known that the stimulation of the basolateral amygdaloid nucleus induces jaw-movements. Less

Report

(4 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] K.Yoshino, et al.: "Functional properties of the primary motor cortex and ventral premotor cortex in the monkey during a visually guided jaw-movement task with a delay period"Brain Research. 852. 414-423 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Y.Yanase, et al.: "Neostriartal stimulation activates tongue-protruder muscle, but not tongue-retractor of facial muscles : an electrical and chemical microstimulation・・・"Brain Research. 893. 282-286 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] T.E.Jones, et al.: "The central termination of trigeminal mesencephalic nucleus in the rat"J.Kyusyu Dental Society. 55. 364-384 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] T.Satoda, et al.: "The sites of origin of projection fibers from the cerebral cortex to the jaw region of the striatum of the rat"Neuroscience Letters. 332. 9-12 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K.Yoshino, S.Kawagishi, Y.Takatsuki, N.Amano: "Functional properties of the primary motor cortex and ventral premotor cortex in the monkey during a visually guided jaw-movement task with a delay period"Brain Res.. 852. 414-423 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Y.Yanase, N.Amano, T.Satoda, Y.Masuda, S.Kawagishi, K.Yoshino: "Neostriatal stimulation activates tongue-protruder muscle, but not tongue-retractor or facial muscles : an electrical and chemical microstimutation study in rats"Brain Res.. 893. 282-286 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] T.E.Jones, K.Yoshino, S.Kawagishi, M.Iwamoto, N.Amano: "The central termination of trigeminal mesencephalic neurons in the rat"J.Kyushu Dent.Soc.. 55. 364-384 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] T.Satoda, N.Amano, Y.Masuda, T.Uchida, Y.Yasui, N.Mizuno: "The sites of origin of projection fibers from the cerebral cortex to the jaw region of the striatum of the rat"Neurosci.Lett.. 332. 9-12 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Y.Yanase, N.Amano, T.Satoda, et al.: "Neostriatal stimulation activates tongue-protruder muscle, but not tongue-retractor or facial muscles : an electrical microstimulation・・・"Brain Research. 893. 282-286 (2001)

    • Related Report
      2002 Annual Research Report
  • [Publications] T.Satoda, N.Amano, et al.: "The sites of origin of projection fibers from the cerebral cortex to the jaw region of the striatum of the rat"Neuroscience Letters. 332. 9-12 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Y.Yanase, et al.: "Neostriatal stimulation activates tongue-protruder muscle, but not tongue-retractor or facial muscles : an electrical and chemical‥‥"Brain Research. 893. 282-286 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Y.Yanase, et al.: "Neostriatal stimulation activates tongue-protruder muscle, but not tongue-retractor or facial muscles : an electrioal"Brain Research. 893・1-2. 282-286 (2001)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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