| Project/Area Number |
12671850
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | OKAYAMA UNIVERSITY |
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Principal Investigator |
TATATSUKA Tomomasa Okayama University, Graduate School of Medicine and Dentistry, Assistant, 大学院・医歯学総合研究科, 助手 (20314700)
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| Co-Investigator(Kenkyū-buntansha) |
KONISHI Norifumi Okayama University, Graduate School of Medicine and Dentistry, Lecturer, 歯学部・附属病院, 講師 (60243466)
TORII Yasuhiro Okayama University, Graduate School of Medicine and Dentistry, Associate Professor, 大学院・医歯学総合研究科, 助教授 (10188831)
橋本 武 岡山大学, 歯学部・附属病院, 助手 (30314701)
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| Project Period (FY) |
2000 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2001: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2000: ¥2,600,000 (Direct Cost: ¥2,600,000)
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| Keywords | Dental Plaque / Biofilm / Oral streptococci / Initial Adherence / Surface-Free Energy / Restorative Material / Confocal Laser Microscopy / Early Colonizer / 界面科学的解析 / PCR-RFLP |
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| Research Abstract |
The purpose of this study is to investigate the initial biofilm formation on the restorative material and human enamel from the viewpoint of thermodynamics. I investigate the initial bacterial flora initially formed on restorative materials in vivo, and initial streptococcal adhesion in vitro. In addition, I investigate the biofilm formed on the restorative material and enamel.
The findings were as follows:
1. There was a different tendency in its proportion of the bacterial flora between resin composite and amalgam, but Oral streptococci was dominant.
2. The bacterial adhesion to dental materials could be explained partially by a thermodynamic approach, but there was a possibility that different mechanism in the initial bacterial adhesion.
3. The growth of the dental biofilm was observed in proportion to time course, but the biofilm of enamel and resin composite were different.
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