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Effect of occlusal interferences on dopamine release of prefrontal cortex in rats

Research Project

Project/Area Number 12671916
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 補綴理工系歯学
Research InstitutionOsaka Dental University

Principal Investigator

MAEDA Teruta  Osaka Dental University, Dentistry, Associate Professor, 歯学部, 助教授 (10103110)

Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 2001: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2000: ¥2,300,000 (Direct Cost: ¥2,300,000)
Keywordsocclusion / autonomic nerve response / stress / SDA
Research Abstract

We investigated the relationship between the change of occlusion and the autonomic nerve response. Seven healthy adult subjects without symptoms of oral function were measured blood pressure (tonometory), heart rate, body temperature, fingertip blood flow, oxygen saturation. All subjects rested in an upright position on the dental chair. A 21 gauge intravenous catheter was inserted, and blood samples at rest were collected. Hemodynamics and plasma catecholamine were used as indication of stress. They wore the stabilization sprint on the maxilla which was divided into three parts (anterior than the first premolar and posterior than the second premolar).
Immediately after wearing every combination of the sprints, the heart rate increased (p=0.053) compared with that in the resting condition, but blood pressure and fingertip blood flow did not change significantly. Five minutes after insertion of only an anterior part of sprint or an anterior and unilateral posterior parts of sprint, the plasma catecholamine were increased (p=0.1). The CV of R-R interval were changed during insertion of sprint, however, the large individual differences were statistically shown (p<0.000001).
The present data suggest that experimental shortened dental arch influenced the autonomic nerve response, but it was not impossible to demonstrate statistically. We continue the experiment with additional conditions for overcoming a fault in the experiment.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (4 results)

All Other

All Publications (4 results)

  • [Publications] 上り口晃成, 呉本晃一, 前田照太, 井上 宏: "各種疼痛刺激が唾液中コルチゾール濃度に及ぼす影響"第11回日本全身咬合学会学術大会プログラム・抄録集. 51 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 前田照太: "バイトプレート(スプリント)の治療効果-歯科補綴学的視点から-"第15回日本顎関節学会総会並・学術大会プログラム・抄録集. 54 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Agariguchi, A., Kuremoto, K., Maeda, T. and Inoue, H.: "Effect of the stress of pains on the salivary cortisol"The abstract of 11^<th> annual meeting of Japanese academy of occlusion and health. 51 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Maeda, T.: "Effect of Bite-plate (Sprint) Therapy -From Prosthetic Point of View"The Abstract of 15^<th> Annual Meeting of Japanese Society for Temporomandibular Joint. 54 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary

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Published: 2000-04-01   Modified: 2016-04-21  

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