ESTABALISHMENY OF AUTOTRANSPLANTATION OF TEETHAND BANK FOR CONSIDERING FUNCTION OF PERIODONTAL LIGAMENT
| Project/Area Number |
12672013
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
矯正・小児・社会系歯学
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| Research Institution | SHOWA UNIVERSITY |
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Principal Investigator |
SAITO Shigeru SHOWA UNIV SCHOOL DENISTRY, LECTURERER, 歯学部, 講師 (20195986)
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| Co-Investigator(Kenkyū-buntansha) |
KURABAYASI Hitomi SHOWA UNIV. SCHOOLOF DENTISTRY, ASSISTANT PROF., 歯学部, 助手 (20255889)
SEKI Kenji SHOWA UNITV SCHOOL OF DENTISTRY, LECTURER, 歯学部, 講師 (00245820)
MOROHASI Tomomi SHOWA UNITV SCHOOL OF DENTISTRY LECTURER, 歯学部, 講師 (10146871)
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| Project Period (FY) |
2000 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2001: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2000: ¥2,500,000 (Direct Cost: ¥2,500,000)
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| Keywords | autotransplanation of teeth / intentional replantation / orthodontic jiggling / quantity of periodontium / root resorption / freeze preserved / enamel matrix derivative / cultured PDL celles |
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| Research Abstract |
The objectives of the present study were to determine whether pre-extraction orthodontic jiggling or enamel matrix derivative could affect the function of periodontium and subsequent root resorption after replantation or autotransplantation of teeth.
In 6 adult male beagle dogs, a labio-lingual jiggling force was applied to the incisors for 4 weeks in maxilla and mandible before extraction. Maxillary incisors in one side were transplanted to the other side, and the mandibular incisors were replanted. Bimaxillarly P1 in one side were transplanted to the other side with or without enamel matrix derivative. All animals were sacrificed 6 to 7 weeks after the autotransplantation and replantation, and the dissected specimen. were prepared for histological study and fluorescence study.
Jjiggling force significantly increased tooth mobility, significantly decreased extraction time and root resorption of transplanted and replanted teeth. In addition, enamel matrix derivative significantly decreased tooth mobility and root resorption after autotransplanation and replantation.
These results suggest that orthodontic jiggling and enamel matrix derivative would be effective tools for clinical autotransplantation of teeth.
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Report
(2 results)
Research Products
(18 results)
