• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Search for New Natural Products from Unutilized North Line Plant Biomass

Research Project

Project/Area Number 12672045
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Chemical pharmacy
Research InstitutionHokkaido University

Principal Investigator

MORITA Hiroshi  Hokkaido Univ., Grad. School of Pharm. Sci., Associate Prof., 大学院・薬学研究科, 助教授 (70220069)

Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2001: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2000: ¥2,200,000 (Direct Cost: ¥2,200,000)
KeywordsDaphniphyllum humile / Celosia argentea / Cephalotaxus harringtonia var. nana / Lycopodium serratum var. serratum / Lycopodium complanatum / Lycopodium chinense / alkaloid / cyclic peptide / 北方系未利用植物資源 / 医薬リード化合物 / 寒冷地 / リコポジウム
Research Abstract

During our search for new natural products from unutilized north line plant biomass, unique alkaloids and peptides have been isolated from Daphniphyllum humile, Cephalotaxus harringtonia var. nana, Lycopodium serratum var. serratum, L complanatum, L. chinense, and Celosia argentea. These nitrogen-containing compounds possessed unique chemical structures and some of them exhibited unique biological activities such as antimitotic, antitumor, and antimalaria activities. From biogenetic points of view, these alkaloids were interesting and we proposed plausible biogenetic paths.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (18 results)

All Other

All Publications (18 results)

  • [Publications] H.Morita: "Senepodine A, A Novel C_<32>N_2 Alkaloid from Lycopodium chinense"Tetrahedron Lett.. 42. 4199-4201 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kobayashi, J.: "Lyconadin A, A Novel Alkaloid from Lycopodium complanatum"J. Org. Chem.. 66. 5901-5904 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kobayashi, J.: "Daphnicyclidins A-H, Novel Hexa-or Penta-Cyclic Alkaloids from Two Species of Daphniphyllum"J. Am. Chem. Soc.. 123. 11402-11408 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kobayashi, J.: "Celogentins A-C, New Antimitotic Cyclic Peptides from the Seeds of Celosia argentea"J. Org. Chem.. 66. 6626-6633 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Morita: "Senepodine A, A Novel C_<22>N_2 Alkaloid from Lycopodiunm chinense"Tetrahedron Lett.. 42. 4199-4201 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] J. Kobayashi: "Lyconadin A, A Novel Alkaloid from Lycopodium complanatum"J. Org. Chem.. 66. 5901-5904 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] J. Kobayashi: "Daphnicyclidins A - H, Novel Hexa - or Penta-Cyclic Alkaloids from Two Species of Daphniphyllum"J. Am. Chem. Soc.. 123. 11402-11408 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] J. Kobayashi: "Celogentins A - C, New Antimitotic Cyclic Peptides from the Seeds of Celosia argentea"J. Org. Chem.. 66. 6626-6633 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Morita: "Senepodine A, A Novel C_<22>N_2 Alkaloid from Lycopodiunm chinense"Tetrahedron Lett.. 42. 4199-4201 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kobayashi, J.: "Lyconadin A, A Novel Alkaloid from Lycopodium complanatum"J. Org. Chem.. 66. 5901-5904 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kobayashi, J.: "Daphnicyclidins A - H, Novel Hexa- or Penta-Cyclic Alkaloids from Two Species of Daphniphyllum"J. Am. Chem. Soc.. 123. 11402-11408 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kobayashi, J.: "Celogentins A - C, New Antimitotic Cyclic Peptides from the Seeds of Celosia argentea"J. Org. Chem.. 66. 6626-6633 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Hiroshi Morita: "Cephalezomines A 〜 F, Potent Cytotoxic Alkaloids from Cephalotaxus harringtonia var.nana"Tetrahedron. 56. 2929-2934 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hiroshi Morita: "Dephnezomines F and G, Novel Alkaloids with 1-Azabicyclo [5.2.2] undecane Moiety from Daphniphyllum humile"J.Org.Chem.. 65. 3558-3562 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hiroshi Morita: "Daphnezomines H, I, J, and K, New Daphnilactone-type and Yuzurimine-type Alkaloids from Daphniphyllum humile"Tetrahedron. 56. 2641-2646 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hiroshi Morita: "Serratezomines A, B, and C, New Alkaloids from Lycopodium serratum var.serratum"J.Org.Chem.. 65. 6241-6245 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Jun'ichi Kobayashi: "Complanadine A, A New Dimeric Alkaloid from Lycopodium complanatum"Tetrahedron Lett.. 41. 9069-9073 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hiroshi Morita: "Picrotoxinin-type and Dendrobine-type Sesquiterpenoids from Dendrobium Snowflake R ed Star"Tetrahedron. 56. 5801-5805 (2000)

    • Related Report
      2000 Annual Research Report

URL: 

Published: 2000-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi