| Co-Investigator(Kenkyū-buntansha) |
NAKAO Reiko Nagasaki University, Health Sciences assistant, 医学部・保健学科, 助手 (80315267)
TASHIRO Takayoshi Nagasaki University, Health Sciences professor, 医学部・保健学科, 教授 (40163456)
松本 麻里 長崎大学, 医療技術短期大学部, 助手 (30295109)
|
|---|
| Budget Amount *help |
¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2001: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2000: ¥2,400,000 (Direct Cost: ¥2,400,000)
|
|---|
| Research Abstract |
The nutritional status, respiratory function and activities of daily living(ADL) were examined in 78 patients with chronic pulmonary emphysema by anthropometric measures, body composition and biochemical examinations. %ideal body weight (%IBW), Body Mass Index (BMl) , fat free mass (FFM) were significantly correlated with FEV_<1.0> and FEV_<1.0 %>. The value of blood serum proteins, prealbumin (PA), retinal-binding protein (RBP) were significantly correlated with FEV_<1.0> and FEV_<1.0 %>. The value of VC, %VC, FEV_<1.0> and FEV_<1.0 %> were significantly lower in the malnourished patients than in the normonoutrished patients. %IBW, BMI, FFM were significantly correlated with the value of ADL. The value of ADL were significantly lower in the malnourished patients than in the normonoutrished patients. In 36 patients, caloric intake was considerably low as compared with that of the same-age man. Carbohydrate were 73.4 %, protein 61.0 %, lipids 61.4 % and total caloric intake 65.1 %, respectively.
The respiratory muscle strength, leg muscle strength, and nutritional status were examined in 16 patients with chronic pulmonary emphysema. The respiratory muscle strength decreased, and the integral expiratory pressure (PEinteg) and the average expiratory pressure (PEave) were significantly correlated with body weight, fat free mass (FFM). Expiratory pressures, PEinteg, PEave and PEmax, were significantly lower in the malnourished patients than in the normonoutrished patients. Inspiratory pressures, PImax and PIave, were significantly lower in the group of decreased leg strength than non-decreased groups.
These results suggested that the nutritional care and the leg muscle strength training may effective to improve the respiratory function, respiratory muscle strength and ADL of the patients with chronic pulmonary emphysema.
|
