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EVAUATION OF CROSS-SECTIONAL AREA OF CORONARY ARTERIES BY CONDUCTANCE CATHETER : TOWORD ITS APPLICATION TO PTCA

Research Project

Project/Area Number 12680832
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionOKAYAMA UNIVERSITY

Principal Investigator

ARAKI Junichl  OKAYAMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE AND DENTISTRY, ASSOCIATE PROFESSOR, 大学院・医歯学総合研究科, 助教授 (80271055)

Co-Investigator(Kenkyū-buntansha) IRIBE Gentaro  OKAYAMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE AND DENTISTRY, ASSISTANT, 大学院・医歯学総合研究科, 助手 (90284885)
SHIMIZU Juichiro  OKAYAMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE AND DENTISTRY, ASSISTANT, 大学院・医歯学総合研究科, 助手 (80294403)
KAJIYA Fumihiko  OKAYAMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE AND DENTISTRY, PROFESSOR, 大学院・医歯学総合研究科, 教授 (70029114)
ITO Haruo  S-I MEDICO-TECH CO., LTD, DIRECTOR, RESEARCH POSITION, 代表取締役(研究職)
Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2001: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2000: ¥2,100,000 (Direct Cost: ¥2,100,000)
KeywordsCONDUCTANCE CATHETER / CORONARY STENOSIS / INTRAVASCULAR ULTRASOUND / CORONARY ANGIOGRAPHY / PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOGRAPHY
Research Abstract

Objectives
The purpose of this study was to evaluate the feasibility of the conductance catheter (CC) method in measuring cross-sectional area (CSA) of small vessels like human coronary arteries.
Methods
Lumen CSA (A) of phantom tubes (2-10 mm in diameter) and excised canine arteries (n = 10, 2.3-4.5 mm in diameter) were measured with 3-F CC (Acc) and intravascular ultrasound (Aus). To investigate the influence of parallel conductance in accuracy of Ace, solution with various resistivities was applied to the surrounding of the arteries (n = 4).
Results
Acc showed an excellent agreement with phantom model CSA. In the excised arteries, Acc and Aus highly correlated (R2 = 0.906) with each other. When the resistivities of the solution surrounding the vessels was changed, Acc-Aus regression lines were similar regardless of different resistivities.
Conclusions
The conductance method is feasible to measure CSA of small vessels like human coronary arteries.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (9 results)

All Other

All Publications (9 results)

  • [Publications] T.Imaoka: "Evaluation of cross-sectional area of small vessels by a miniature conductance catheter : Toward its application to coronary stenosis"Cardiovascular Engineering : An International Journal. (in press). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] J.Araki: "Assessment of total Ca^<2+> handling for excitation-contraction coupling in beating left ventricle"Journal of Mechanics in Medicine and Biology. 1・2. 123-138 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] G.Iribe: "New calculation of internal Ca^<2+> recirculation fraction from alternans decay of postextrasystolic potentiation"Japanese Journal of Physiology. 51・2. 143-149 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T. IMAOKA: "EVALUATION OF CROSS-SECTIONAL AREA OF SMALL VESSELS BY A MINIATURE CONDUCTANCE CATHETER : TOWARD ITS APPLICATION TO CORONARY STENOSIS"CARDIOVASCULAR ENGINEERING : AN INTERNATIONAL JOURNAL. (in press). (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] J. ARAKI: "ASSESSMENT OF TOTAL CA2+ HANDLING FOR EXCITATION CONTRACTION COUPLING IN BEATING LEFT VENTRICLE"JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY. 1-2. 123-138 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] G. IRIBE: "NEW CALCULATION OF INTERNAL CA2+ RECIRCULATION FRACTION FROM ALTERNANS DECAY OF POSTEXTRASYSTOLIC POTENTIATION"JAPANESE JOURNAL OF PHYSIOLOGY. 51-2. 143-149 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T.Imaoka: "Evaluation of cross-sectional area of small vessels by a miature conductance catheter : Toward its application to coronary stenosis"Cardiovascular Engineering : An International Journal. (in press). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] J.Araki: "Assessment of total Ca^<2+> handling for excitation-contraction coupling in beating left ventricle"Journal of Mechanics in Medicine and Biology. 1・2. 123-138 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] G.Iribe: "New calculation of internal Ca^<2+> recirculation fraction from alternans decay of postextrasystolic potentiation"Japanese Journal of Physiology. 51・2. 143-149 (2001)

    • Related Report
      2001 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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