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Measurements of acoustic properties of biomacromolecules using bio-ultrasonic micro-spectroscopy

Research Project

Project/Area Number 12680855
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionIchinoseki National College of Technology

Principal Investigator

AKASHI Naoyuki  Ichinoseki National College of Technology Associate Professor, 電気工学科, 助教授 (50250692)

Project Period (FY) 2000 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2002: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2001: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2000: ¥2,000,000 (Direct Cost: ¥2,000,000)
Keywordsbio-ultrasonic micro-spectroscopy / biomacromolecules / bioultrasonic spectroscopy system / acoustic property / frequency dependence / a aqueous solution of glucose / polyester film / VHF / UHF range / VHF帯 / べき乗 / 超音波スペクトロスコピーシステム / ポリエステルフィルム / 温度依存性 / 糖類水溶液 / デキストラン
Research Abstract

The acoustic parameters of velocity, attenuation, impedance, and density of polyester film as a model for biomacromolecules were measured in the frequency range 60 to 220 MHz using the bioultrasonic spectroscopy system. Frequency dependences of velocity and attenuation in the frequency range were observed. The temperature dependence of the acoustic parameters of polyester film is also measured in the temperature range 20-26℃. Attenuation increases and velocity decreases as temperature increases.
In order to measure the frequency characteristics of velocity for a sample with velocity dispersion, velocity measurement using a complex mode was introduced. Water as liquid material and polyester film as solid material were taken and velocity measurements using the complex mode were performed in the frequency range 100 to 200 MHz. Velocity dispersion was not observed for water and the dispersion of 0.02(m/s)/MHz was measured for polyester film.
We proposed using the exponent on frequency of the attenuation coefficient as a characterizing parameter. The relation between the exponent on frequency and the relaxation parameters was investigated. In order to carry out numerical calculations, a model for a single relaxation process was employed. For example, from the measured attenuation coefficients of a 25% aqueous solution of glucose in the frequency range 20 to 700 MHz, the relaxation time and the parameter were determined.

Report

(4 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] 明石尚之, 櫛引淳一, Floyd Dunn: "生体超音波スペクトロスコピー・システムによる生体物質の音響特性の周波数依存性解析法"日本音響学会講演論文集(2003.3). 1205-1206 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 櫛引淳一, 荒川元孝, 明石尚之, Floyd Dunn: "VHF/UHF帯における線形・非線形生体超音波スペクトロスコピー・システムの開発"日本音響学会講演論文集(2003.3). 1207-1208 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Zhang Dong, Jun-ichi Kushibiki, Naoyuki Akashi, Floyd Dunn: "Sound diffraction effects in the measurement of the nonlinearity parameter for liquid specimens at very high frequencies"日本音響学会講演論文集(2002.3). 1065-1066 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 猪熊洋輔, 櫛引淳一, 西野秀郎, 明石尚之: "生体超音波スペクトロスコピー・システムによるグルコース溶液の音響特性測定"日本音響学会講演論文集(2002.3). 961-962 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 明石尚之, 吉田隆廣, 櫛引淳一: "VHF帯におけるポリエステルフィルムの縦波音響特性の温度依存性"日本音響学会講演論文集(2002.3). 967-968 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 明石尚之, 櫛引淳一: "VHF帯におけるポリエステルフィルムの縦波音響特性測定"日本音響学会講演論文集(2001.3). 929-930 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] N. Akashi, J. Kushibiki, and F. Dunn: "A method of analysis for frequency dependence of acoustic properties of biological tissues by the bioultrasonic spectroscopy system"Reports of Spring Meeting Acoust. Soc. Japan. 1205-1206 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] J. Kushibiki, M. Arakawa, N. Akashi, and F. Dunn: "Development of a linear and nonlinear bioultrasonic spectroscopy system in the VHF/UHF range"Reports of Spring Meeting Acoust. Soc. Japan. 1207-1208 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Z. Dong, J. Kushibiki, N. Akashi, and F. Dunn: "Sound diffraction effects in the measurement of the nonlinearity parameter for liquid specimens at very high frequencies"Reports of Spring Meeting Acoust. Soc. Japan. 1065-1066 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Y. Inokuma, J. Kushibiki, H. Nishino, and N. Akashi: "Frequency and temperature dependences of acoustic properties of polyester film in the VHF range"Reports of Spring Meeting Acoust. Soc. Japan. 967-968 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] N. Akashi, T. Yoshida, and J. Kushibiki: "Frequency and temperature dependences of acoustic properties of polyester film in the VHF range"Reports of Spring Meeting Acoust. Soc. Japan. 967-968 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] N. Akashi and J. Kushibiki: "Measurements of acoustic properties of polyester film by using VHF range longitudinal waves"Reports of Spring Meeting Acoust. Soc. Japan. 929-930 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 明石尚之, 櫛弓淳一, Floyd Dunn: "生体超音波スペクトロスコピー・システムによる生体物質の音響特性の周波数依存性解析法"日本音響学会講演論文集(2003.3). 1205-1206 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 櫛引淳一, 荒川元孝, 明石尚之, Floyd Dunn: "VHF/UHF帯における線形・非線形生体超音波スペクトロスコピー・システムの開発"日本音響学会講演論文集(2003.3). 1207-1208 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 明石尚之, 吉田隆廣, 櫛引淳一: "VHF帯におけるポリエステルフィルムの縦波音響特性の温度依存性"日本音響学会講演論文集(2002.3). 967-968 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 明石尚之,櫛引淳一: "VHF帯におけるポリエステルフィルムの縦波音響特性測定"日本音響学会講演論文集(2001.3). 929-930. (2001)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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