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A new progress of physical therapy for the purpose of prevention of cerebrovascular and infeetious diseases

Research Project

Project/Area Number 12832011
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research InstitutionGunma University

Principal Investigator

KUBOTA Kazuo  School of Medicine, Gunma University Associate Professor, 医学部, 助教授 (00102244)

Co-Investigator(Kenkyū-buntansha) KURABAYASHI Hitoshi  School of Medicine, Gunma University Associate Professor, 医学部, 講師 (70192036)
Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,900,000)
Fiscal Year 2001: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2000: ¥2,700,000 (Direct Cost: ¥2,700,000)
Keywordsrehabilitation / cerebrovascular disease / physical therapy / chronic obstructive pulmonary disease / breathing exercise / suppressor / inducer T cell / helper / inducer T ceil / immune function / 凝固・線溶系 / 温浴 / tPA / PAI-I / 血小板の活性化
Research Abstract

We investigated the change in immune function during rehabilitative physical therapy in patients with cerebrovascular and chronic obstructive pulmonary diseases.
The effect of a 2-month period of physical therapy on immune function was examined in 11 patients with cerebrovascular disease. Compared with the similar patients who did not receive physical therapy, the ratio of CD4/CD8 cells, response of lymphocytes to mitogens suppressor/inducer T cells, and helper/inducer T cells were increased significantly. Although antibody-dependent cellular cytotoxicity and interleukin-2 receptor were also increased significantly, natural killer cell activity and serum levels of interleukin-2 and inerleukin-6 were not changed
The effect of a 2-month period of physical therapy using breathing pxercise in a pool on immune function was examined in 10 patients with chronic obstructive pulmonary disease. Compared with the similar patients who did not receive physical therapy, CD4-positive cells, the ratio of CD4/CD8 cells, and response of lymphocytes to mitogens were increased significantly. However, serum levels of immunoglobulin were not changed.
These findings suggest that physical therapy may increase the immune function in patients with cerebrovascular and chronic obstructive pulmonary diseases.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] Kurabayashi H: "The effects of hydraulic pressure on atrial natriuretic peptide during rehabilitative head-out water immersion"Life Sciences. 69. 1017-1021 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 田村耕成: "温泉浴の凝固調節因子に及ぼす影響"日本温泉気候物理医学会雑誌. 64. 141-144 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 倉林 均: "温泉地における旅行者の急性疾患発症とeconomy class syndrome"日本温泉気候物理医学会雑誌. 64. 164-165 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 倉林 均: "静水圧による胸囲、腹囲、大腿周径及び下腿周径の変化"日本温泉気候物理医学会雑誌. 64. 199-202 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 久保田一雄: "高齢者の入浴"臨牀と研究. 78. 2129-2131 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kurabayashi H, et al: "The effects of hydraulic pressure on atrial natriuretic peptide during rehabilitative head-out water immersion"Life Sci. 69. 1017-1021 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Tamura K, et al: "Effect of hot-spring bathing on the control factors of coagulation"J Jpn Assoc Phys Med Balneol Climatol. 64. 141-144 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kurabayashi H, et al: "Acute diseases of travelers in spa-resorts associated with economy class syndrome"J Jpn Assoc Phys Med Balneol Climatol. 64. 164-165 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kurabayashi H, et al: "Analysis of the circumferences of chest, abdomen, thigh and calf during head-out water immersion"J Jpn Assoc Phys Med Balneol Climatol. 64. 199-202 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kurabayashi H.: "The effects of hydraulic pressure on atrial natriuvetic peptide during rehabilitative head-out water immersion"Life Sciences. 69. 1017-1021 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 田村耕成: "温泉浴の凝固調節因子に及ぼす影響"日本温泉気候物理医学会雑誌. 64. 141-144 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 倉林 均: "温泉地における旅行者の急性疾患発症とeconomy class syndrome"日本温泉気候物理医学会雑誌. 64. 164-165 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 倉林 均: "静水圧による胸囲、腹囲、大腿周径及び下腿周径の変化"日本温泉気候物理医学会雑誌. 64. 199-202 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 久保田一雄: "高齢者の入浴"臨牀と研究. 78. 2129-2131 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 田村耕成: "水治療における水温の血小板および凝固線溶系に及ぼす影響"リハビリテーション医学. 38(1). 34-37 (2001)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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