最適な糖尿病スクリーニング法の開発とその県レベルコホートにおける実証

• Project/Area Number: 12J00046
• Research Category: Grant-in-Aid for JSPS Fellows
• Allocation Type: Single-year Grants
• Section: 国内
• Research Field: Metabolomics
• Research Institution: University of Tsukuba
• Principal Investigator: 平安座 依子 筑波大学, 大学院人間総合科学研究科, 特別研究員(DC1)
• Project Period (FY): 2012 – 2014-03-31
• Project Status: Declined (Fiscal Year 2013)
• Budget Amount: ¥1,800,000 (Direct Cost: ¥1,800,000); Fiscal Year 2013: ¥900,000 (Direct Cost: ¥900,000); Fiscal Year 2012: ¥900,000 (Direct Cost: ¥900,000)
• Keywords: 糖尿病 / スクリーニング / リスクスコア / 追跡調査 / 臨床疫学 / 血糖 / Glycosylated Hemoglobin A / リスク評価 / 危険因子

Research Abstract

未診断糖尿病発見リスクスコアを当てはめるべき集団を特定すべく、糖尿病関連因子についての検討をさらに発展させた。生活状況と糖尿病との関連を検討した結果、単身生活の日本人男性では、未診断糖尿病を有する可能性が高いことを認めた(Heianza Y, Diabet Med 2013 ; 30 : 1355-1359)。また、特に過体重、喫煙者や運動習慣の無い者において、単身生活は糖尿病と有意に関連しており、単身生活と未診断の糖尿病との関連は、部分的に、改善可能な他の生活習慣に影響されている可能性が示唆された。さらに、日本人女性では特に閉経後に加齢とは独立して糖尿病を有する可能性が高まる可能性を見出した(Heianza Y, et al. Diabetes Care 2013 ; 36 : 4007-4014)。閉経前女性と比較して、閉経後女性では、加齢、体格指標(BMI)や生活習慣因子とは独立して、糖尿病を有する可能性が有意に高かった。男性の有する糖尿病保有リスクには匹敵しないものの、閉経後女性では加齢とは独立して高血糖状態と関連する可能性が認められた。以上の結果より、単身生活の男性や閉経後女性などに対する糖尿病スクリーニングの働きかけが有効であると思われた。前年度に開発した糖尿病リスクスコアの妥当性を検証するため、新潟県の健康診査・人間ドック受診者のデータを活用したvalidation研究を今年度下旬より取り組み始めたところである。来年度中には研究結果が得られると思われる。
一方、糖尿病を指摘されても、多くの者が通院治療を開始せずに糖尿病を放置していることが世界的に問題となっている。申請者らがレセプトデータを活用した糖尿病スクリーニング勧果の検証を実施した結果において、糖尿病を未治療・放置することと比較して、高血糖を指摘された後すぐに通院治療を開始・継続することは、良好な血糖コントロールに寄与することが科学的に証明された。

Strategy for Future Research Activity

(抄録なし)

Research Products

• [Journal Article] Association of living alone with the presence of undiagnosed diabetes in Japanese men : the role of modifiable risk factors for diabetes : Toranom on Hospital Health Management Center Study 13 (TOPICS 13) (2013)
  • Author(s): Heianza Y, Arase Y, Kodama S, Hsieh SD, Tsuji H, Saito K, Shimano H, Hara S, Sone H.
  • Journal Title: Diabetic medicine Volume: 30 Issue: 11 Pages: 1355-1359
  • DOI: 10.1111/dme.12255
  • Peer Reviewed
• [Journal Article] Effect of Postmenopausal Status and Age at Menopause on Type 2 Diabetes and Prediabetes in Japanese Individuals : Toranomon Hospital HealthManagement Center Study 17 (TOPICS17) (2013)
  • Author(s): Heianza Y, Arase Y, Kodama S, Hsieh SD, Tsuji H, Saito K, Shimano H, Hara S, Sone H.
  • Journal Title: Diabetes Care Volume: 36 Issue: 12 Pages: 4007-4014
  • DOI: 10.2337/dc13-1048
  • Peer Reviewed
• [Journal Article] Quality and accuracy of Internet information concerning a healthy diet (2013)
  • Author(s): Hirasawa R, Yachi Y, Yoshizawa S, Horikawa C, Heianza Y, Sugawara A, Sone Y, Kondo K, Shimano H, Saito K, Kodama S, Sone H.
  • Journal Title: Int J Food Sci Nutr Volume: 64 Issue: 8 Pages: 1007-1013
  • DOI: 10.3109/09637486.2013.812620
  • Peer Reviewed
• [Journal Article] Development of a Screening Score for Undiagnosed Diabetes and Its Application in Estimating Absolute Risk of Future Type 2 Diabetes in Japan: Toranomon Hospital Health Management Center Study 10 (TOPICS10) (2013)
  • Author(s): Heianza Y, Arase y ; Saito K, Hsieh SD, Tsuji H, Kodama S, Tanaka S, Ohashi Y, Shimano H, Yamada N, Hara S, Sone H
  • Journal Title: The Journal of clinical endocrinology and metabolism Volume: 98 Issue: 3 Pages: 1051-1060
  • DOI: 10.1210/jc.2012-3092
  • Peer Reviewed
• [Journal Article] Role of alcohol drinking pattern in type 2 diabetes 1n Japanese men : the Toranomon Hospital Health Management Center Study 11 (TOPICS 11) (2013)
  • Author(s): Heianza Y, Arase Y; Saito K, Tsuji H, Fujihara K, Hsieh SD, Kodama S, Shimano H, YamadaN, Hara S, Sone H
  • Journal Title: The American journal of clinical nutrition Volume: 97 Issue: 3 Pages: 561-568
  • DOI: 10.3945/ajcn.112.043364
  • Peer Reviewed
• [Journal Article] Association Between Physical Activity and Risk of All-Cause Mortality and Cardiovascular Disease in Patients With Diabetes : A meta-analysis (2013)
  • Author(s): Kodama S, Tanaka S, HeianzaY, Fujihara K, Horikawa C, Shimano H, Saito K, Yamada N, Ohashi Y, Sone H
  • Journal Title: Diabetes Care Volume: 36 Issue: 2 Pages: 471-479
  • DOI: 10.2337/dc12-0783
  • Peer Reviewed
• [Journal Article] Longitudinal trajectories of HbAlc and fasting plasma glucose levels during the development of type 2 diabetes : the Toranomon Hospital Health Management Center Study 7 (TOPICS 7) (2012)
  • Author(s): Heianza Y, Arase Y, Fujihara K, Hsieh SD, Saito K, Tsuji H, Kodama S, Yahagi N, Shimano H, Yamada N, Hara S, Sone H.
  • Journal Title: Diabetes Care Volume: 35 Issue: 5 Pages: 1050-1052
  • DOI: 10.2337/dc11-1793
  • Peer Reviewed
• [Journal Article] High normal HbA(1c) levels were associated with impaired insulin secretion without escalating insulin resistance in Japanese individuals : the Toranomon Hospital Health Management Center Study 8 (TOPICS 8) (2012)
  • Author(s): Heianza Y, Arase y Fujihara K, Tsuji H, Saito K, Hsieh SD, Kodama S, Shimano H, YamadaN, Hara S, Sone H
  • Journal Title: Diabetic medicine Volume: 29 Pages: 1285-1290
  • Peer Reviewed
• [Journal Article] Screening for pre-diabetes to predict future diabetes using various cut-off points for HbA(1c) and impaired fasting glucose : the Toranomon Hospital Health Management Center Study 4 (TOPICS 4) (2012)
  • Author(s): Heianza Y, Arase y Fujihara K, Tsuji H, Saito K, Hsieh SD, Kodama S, Shimano H, YamadaN, Hara S, Sone H
  • Journal Title: Diabetic medicine Volume: 29
  • Peer Reviewed
• [Journal Article] Development of a new scoring system for predicting the 5 year incidence of type 2 diabetes 1n Japan : the Toranomon Hospital Health Management Center Study 6 (TOPICS 6) (2012)
  • Author(s): Heianza Y, Arase Y, Hsieh SD, Saito K, Tsuji H, Kodama S, Tanaka S, Ohashi Y, Shimano H, Yamada N, Hara S, Sone H,
  • Journal Title: Diabetologia Volume: 55 Pages: 3213-3223
  • Peer Reviewed
• [Journal Article] Low lung function and risk of type 2 diabetes in Japanese men : the Toranomon Hospital Health Management Center Study 9 (TOPICS 9) (2012)
  • Author(s): Heianza YI Arase y Tsuji H, Saito K, Amakawa K, Hsieh SD, Kodama S, Shimano H, YamadaN, Hara S, Sone H
  • Journal Title: Mayo Clinic proceedings. Mayo Clinic Volume: 87 Issue: 9 Pages: 853-861
  • DOI: 10.1016/j.mayocp.2012.04.016
  • Peer Reviewed
• [Journal Article] Impact of introducing HbAlc into the diagnostic criteria on prevalence and cardiovascular risk profiles of individuals with newly diagnosed diabetes in Japan : the Toranomon Hospital Health Management Center Study 2 (TOPICS 2) (2012)
  • Author(s): Heianza Y, Hara S, Arase y Saito K, Tsuji H, Kodama S, Hsieh SD, Mori Y, Okubo M, Yamada N, Kosaka K, Sone H
  • Journal Title: Diabetes research and clinical practice Volume: 95 Issue: 2 Pages: 283-290
  • DOI: 10.1016/j.diabres.2011.10.024
  • Peer Reviewed
• [Journal Article] Quality of Internet information related to the Mediterranean diet (2012)
  • Author(s): Hirasawa R, Saito K, Yachi y lbe Y, Kodama S, Asumi M, Horikawa C, Saito A, Heianza Y, Kondo K, Shimano H, Sone H.
  • Journal Title: Public health nutrition Volume: 15 Issue: 5 Pages: 885-893
  • DOI: 10.1017/s1368980011002345
  • Peer Reviewed
• [Journal Article] Comparisons of the Strength of Associations With Future Type 2 Diabetes Risk Among Anthropometric Obesity Indicators, Including Waist-to-Height Ratio : A Meta-Analysis (2012)
  • Author(s): Kodama S, Horikawa C, Fujihara K, Heianza Y, Hirasawa R, Yachi y Sugawara A, Tanaka S, Shimano H, Iida KT, Saito K, Sone H
  • Journal Title: American journal of epidemiology Volume: 176 Issue: 11 Pages: 959-969
  • DOI: 10.1093/aje/kws172
  • Peer Reviewed
• [Journal Article] Impact of psychological stress caused by the great east japan earthquake on glycemic control in patients with diabetes (2012)
  • Author(s): Fujihara K, Saito A, Heianza Y, Gibo H, Suzuki H, Shimano H, Saito K, Kodama S, Yamada N, Sone H
  • Journal Title: Experimental and clinical endocrinology & diabetes Volume: 120 Issue: 09 Pages: 560-563
  • DOI: 10.1055/s-0032-1314873
  • Peer Reviewed
• [Presentation] 現在BMIと20歳時や生涯最大BMIを組み合わせた高血圧発症予測の縦断的検討. (2014)
  • Author(s): 平安座 依子, 児玉 暁, 齋藤 和美, 島野 仁, 田中 司朗, 荒瀬 康司, 原 茂子, 曽根 博仁. (仙台), 2014年1月23日～1月25日(ポスター)
  • Organizer: 第24回日本疫学会学術総会
  • Place of Presentation: 日立システムズホール仙台(仙台市青年文化センター)(仙台)
• [Presentation] ヘモグロビンAlc検査による糖尿病スクリーニングとその後の通院治療開始が血糖コントロールに与える影響. (2014)
  • Author(s): 平安座 依子, 羽入 修, 鈴木 亜希子, 児玉 暁, 島野 仁, 曽根 博仁.
  • Organizer: 第24回日本疫学会学術総会
  • Place of Presentation: 日立システムズホール仙台(仙台市青年文化センター)(仙台)
• [Presentation] 糖尿病と閉塞性睡眠時無呼吸症候群の関連性及び方向性のメタ解析 (2013)
  • Author(s): 藤原和哉,児玉暁,堀川千嘉,平安座 依子,由澤咲子,菅原歩美,平澤玲子,谷内洋子,斎藤和美,島野仁,山田信博,曽根博仁
  • Organizer: 第23回日本疫学会学術総会
  • Place of Presentation: 大阪大学(大阪)
  • Year and Date: 2013-01-26
• [Presentation] 2型糖尿病発症に至るまでのBMIの長期変化に関する大規模縦断的検討:TOPICS (2013)
  • Author(s): 平安座 依子,原 茂子,謝 勲東,斎藤 和美,辻 裕之,羽入 修,児玉 暁,島野 仁,山田 信博,荒瀬 康司,曽根 博仁
  • Organizer: 第23回日本疫学会学術総会
  • Place of Presentation: 大阪大学(大阪)
  • Year and Date: 2013-01-25
• [Presentation] ウェスト周囲長・身長比による2型糖尿病予測スクリーニング精度の検討:TOPICS (2013)
  • Author(s): 平安座 依子,謝 勲東,児玉 暁,辻 裕之,斎藤 和美,島野 仁,荒瀬 康司,原 茂子,曽根 博仁
  • Organizer: 第23回日本疫学会学術総会
  • Place of Presentation: 大阪大学(大阪)
  • Year and Date: 2013-01-25
• [Presentation] 飲酒パターンと2型糖尿病発症リスク-10年間の縦断調査 : TOPICS (2013)
  • Author(s): 平安座 依子,原 茂子,謝 勲東,斎藤 和美,辻 裕之,児玉 暁,荒瀬 康司,島野 仁,山田 信博,曽根 博仁
  • Organizer: 第16回日本病態栄養学会年次学術集会
  • Place of Presentation: 国立京都国際会館(京都)
  • Year and Date: 2013-01-13
• [Presentation] 糖尿病スクリーニングスコアの開発とその後の発症リスク予測可能性の検討:TOPICS (2013)
  • Author(s): 平安座 依子,原 茂子,謝 勲東,斎藤 和美,辻 裕之,児玉 暁,荒瀬 康司,島野 仁,山田 信博,曽根 博仁
  • Organizer: 第16回日本病態栄養学会年次学術集会
  • Place of Presentation: 国立京都国際会館(京都)
  • Year and Date: 2013-01-13
• [Presentation] 単身生活や他の生活習慣と2型糖尿病に関する大規模検討 : The Toranomon Hospital Health Management Center Study (2013)
  • Author(s): 平安座 依子, 原 茂子, 謝 勲東, 齋藤 和美, 辻 裕之, 児玉 暁, 荒瀬 康司, 島野 仁, 山田 信博, 曽根 博仁.
  • Organizer: 第67回日本栄養・食糧学会大会
  • Place of Presentation: 名古屋大学(名古屋)
• [Presentation] 特定健診による要受診判定後の医療機関受診率とその推移. (2013)
  • Author(s): 羽入修, 平安座依子, 古川和郎, 川田亮, 大澤妙子, 山本正彦, 皆川真一, 鈴木裕美, 山田絢子, 山田貴穂, 鈴木亜希子, 曽根博仁.
  • Organizer: 第56回日本糖尿病学会年次学術集会
  • Place of Presentation: ホテル日航熊本他(熊本)
• [Presentation] 単身生活と実診断2型糖尿病に関する大規模検討 : The Toranomon Hospital Health Management Center Study. (2013)
  • Author(s): 平安座 依子, 原 茂子, 児玉 暁, 謝 勲東, 辻 裕之, 齋藤 和美, 島野 仁, 荒瀬 康司, 曽根 博仁.
  • Organizer: 第56回日本糖尿病学会年次学術集会
  • Place of Presentation: ホテル日航熊本 他(熊本)
• [Presentation] Prediction of the development of hypertension by body mass index history in Japan : Toranomon Hospital Health Management Center Study (TOPICS). (2013)
  • Author(s): Heianza Y, Arase Y, Kodama S, Suzuki A, Saito K, Hsieh SD, Shimano H, Hara S, Sone H.
  • Organizer: Asia-Pacific Diabetes and Obesity Study Group symposium
  • Place of Presentation: Tokyo International Forum (Tokyo)
• [Presentation] Comparison of Various Body Mass Index Histories to Identify Undiagnosed Diabetes in Japanese Men and Women : Toranomon Hospital Heaith. (2013)
  • Author(s): Yoshizawa S, Heianza Y, Arase Y, Saito K, Hsieh SD, Tsuji H, Hanyu O, Suzuki A, Tanaka S, Kodama S, Shimano H, Hara S, Sone H.
  • Organizer: Asia-Pacific Diabetes and Obesity Study Group symposium
  • Place of Presentation: Tokyo International Forum (Tokyo)
• [Presentation] Trajectory of body mass index before the development of type 2 diabetes in Japanese men : Toranomon hospital health management center study (TOPICS). (2013)
  • Author(s): Heianza Y, Arase Y, Hara S, Fujihara K, Hsieh SD, Sugawara A, Suzuki A, Hanyu O, Saito K, Kodama S, Shimano H, Sone H.
  • Organizer: 49th European Association for the Study of Diabetes (EASD) Annual Meeting
  • Place of Presentation: The Fira de Barcelona's Gran Via exhibition centre (Barcelone, Spain)
• [Presentation] Predictive ability of simple clinical information without blood tests for future incident diabetes : a meta-allalysis. (2013)
  • Author(s): Yoshizawa S, Kodama S, Fujihara K, Horikawa C, Sugawara A, Heianza Y, Yachi Y, Tanaka S, Minagawa S, Yamada T, Suzuki A, Hanyu O, Kodama S, Shimano H, Sone H.
  • Organizer: 49th European Association for the Study of Diabetes (EASD) Annual Meeting
  • Place of Presentation: The Fira de Barcelona's Gran Via exhibition centre (Barcelone, Spain)
• [Presentation] Simple self-reported anger and memory loss as risk factors for the development of type2 diabetes in Japanese individuals (2013)
  • Author(s): Suzuki A, Heianza Y, Arase Y, Hara S, Hsieh S, Yamada T, Fujihara K, Saito K, Kodama S, Hanyu O, Sone H.
  • Organizer: 49th European Association for the Study of Diabetes (EASD) Annual Meeting
  • Place of Presentation: The Fira de Barcelona's Gran Via exhibition centre (Barcelone, Spain)
• [Presentation] Normal fasting glucose and HbAlc levels and the development of hypertension in Japanese individuals. (2013)
  • Author(s): Yamada T, Heianza Y, Kodama S, Arase Y, Saito K, Suzuki K, Hara S, Hanyu O, Sone H.
  • Organizer: 49th European Association for the Study of Diabetes (EASD) Annual Meeting
  • Place of Presentation: The Fira de Barcelona's Gran Via exhibition centre (Barcelone, Spain)
• [Presentation] Utility of Elevated 1-h Glucose Values for Assessment of Pathogenesis of Type 2 Diabetes in Japanese Individuals. (2013)
  • Author(s): Heianza Y, Arase Y, Kodama S, Hsieh SD, Fujihara K, Tanaka S, Suzuki A, Hanyu O, Saito K, Shimano H, Hara S, Sone H.
  • Organizer: 73rd American Diabetes Association Scientific Sessions
  • Place of Presentation: McCormick Place Convention Center (Chicago, USA)
• [Presentation] Relationship of Living Alone with Undiagnosed Diabetes in Japan : Toranomon Hospital Health Management Center Study (2013)
  • Author(s): Heianza Y, Arase Y, Kodama S, Hsieh SD, Sugawara A, Tanaka S, Suzuki A, Saito K, Hanyu O, Saito K, Shimano H, Hara S, Sone H.
  • Organizer: 73rd American Diabetes Association Scientific Sessions
  • Place of Presentation: McCormick Place Convention Center (Chicago, USA)
• [Presentation] HbA1C in theFirst Trimester Predicts Gestational Diabetes Independent of Fasting Glucose in Japanese Pregnant Women : TWC Study. (2013)
  • Author(s): Yachi Y, Tanaka Y, Sugawara A, Nishibata I, Horikawa C, Heianza Y, Fujihara K, Kodama S, Hanyu O, Sone H.
  • Organizer: 73rd American Diabets Association Scientific Sessions.
  • Place of Presentation: McCormick Place Convention Center (Chicago, USA)
• [Presentation] Effects of Recommendation Notices for Clinic Visits by Nationwide Health Screening System in Japan. (2013)
  • Author(s): Hanyu O, Heianza Y, Furukawa K, Kawada R, Yamamoto M, Osawa T, Suzuki H, Minagawa S, Yamada T, Yamada A, Suzuki A, Sone H.
  • Organizer: 73rd American Diabetes Association Scientific Sessions
  • Place of Presentation: McCormick Place Convention Center (Chicago, USA)
• [Presentation] Relationship between Body Weight (BW) Gain from Early Adultbood and Incident Type 2 Diabetes (T2DM)-A Meta-Analysis. (2013)
  • Author(s): Kodama S, Horikawa C, Fujihara K, Tajima R, Heianza Y, Hirasawa R, Yachi Y, Iida KT, Shimano H, Hanyu O, Sone H.
  • Organizer: 73rd American Diabetes Association Scientific Sessions
  • Place of Presentation: McCormick Place Convention Center (Chicago, USA)
• [Presentation] Relationship between Diabetic Neuropathy and Sleep Apnea Syndrome-A Meta-Analysis. (2013)
  • Author(s): Fujihara K, Kodama S, Horikawa C, Sugawara A, Heianza Y, Yachi Y, Saito K, Shimano H, Hanyu O, Sone H.
  • Organizer: 73rd American Diabetes Association Scientific Sessions
  • Place of Presentation: McCormick Place Convention Center (Chicago, USA)
• [Presentation] Cross-sectional and longitudinal relationships between dairy consumption and metabolic syndrome (2012)
  • Author(s): Horikawa C, Kodama S, Heianza Y. Yoshizawa S, Sugawara A, Hirasawa R, Yachi Y, Saito K, Sone H
  • Organizer: 9th IDF-WPR Congress and 4th AASD Scientific Meeting
  • Place of Presentation: 国立京都国際会館(京都)
  • Year and Date: 2012-11-26
• [Presentation] Development and Validation of Screening Score for Detecting Undiagnosed Diabetes and Estimating Risk of Future Diabetes (2012)
  • Author(s): Heianza Y, Yasuji Y , Saito K, Tsuji H, Fujihara K, Hsieh S.D, Kodama S, Shimano H, Yamada N, Hara S, Sone H
  • Organizer: 9th IDF-WPR Congress and 4th AASD Scientific Meeting
  • Place of Presentation: 国立京都国際会館(京都)
  • Year and Date: 2012-11-25
• [Presentation] Roles of Alcohol Drinking Pattern in Type 2 Diabetes in Japanese Men : Toranomon Hospital Health Management Center Study (2012)
  • Author(s): Heianza Y, Yasuji Y, Saito K, Tsuji H, Fujihara K, Hsieh Sd, Kodama S, Shimano H, YamadaN, Hara S, Sone H
  • Organizer: 9th IDF-WPR Congress and 4th AASD Scientific Meeting
  • Place of Presentation: 国立京都国際会館(京都)
  • Year and Date: 2012-11-25
• [Presentation] Comparison of current BMI and BMI histories to screen for undiagnosed diabetes in Japanese men : Tbranomon Hospital Health Management Center Study (2012)
  • Author(s): Yoshizawa S, Heianza Y, Horikawa C, Hara S, Saito K, Kodama S, S.D. Hsieh, Tsuji H, Yamada N, Arase Y, Sone H
  • Organizer: 48th EASD Annual Meeting
  • Place of Presentation: Berlin, Germany
  • Year and Date: 2012-10-04
• [Presentation] Comparison of Framingham risk score, UKPDS risk engine, maximum-IMT, and LDL-C/HDL-C ratio for predicting coronary plaque in asymptomatic patients with type 2 diabetes (2012)
  • Author(s): Fujihara K, Suzuki H, Sato A, Kodama S, Heianza Y, Ishizu T, Saito K, Iwasaki H, KobayashiK, Yatoh S, Takahashi A, Yamada N, Sone H, Shimano H
  • Organizer: 48th EASD Annual Meeting
  • Place of Presentation: Berlin, Germany
  • Year and Date: 2012-10-04
• [Presentation] Development and evaluation of screening score for detecting undiagnosed diabetes and estimating absolute risk of future type 2 diabetes: TOPICS (2012)
  • Author(s): Heianza Y, Hara S, Yoshizawa S, Kodama S, Saito K, Hsieh S, Horikawa C, Tsuji H, Yamada N, Arase Y, Sone H
  • Organizer: 48th EASD Annual Meeting
  • Place of Presentation: Berlin, Germany
  • Year and Date: 2012-10-03
• [Presentation] Association between pulse pressure and cardiovascular risk in diabetesmellitus: a meta-analysis (2012)
  • Author(s): Horikawa C, Kodama S, Heianza Y, Yoshizawa S, Fujihara K, Tanaka S, Iida T. K, Yachi Y, Ohashi Y, Sone H
  • Organizer: 48th EASD Annual Meeting
  • Place of Presentation: Berlin, Germany
  • Year and Date: 2012-10-02
• [Presentation] 未診断糖尿病の検出には現在の体重より過去の最大体重の方が有効である (2012)
  • Author(s): 児玉 暁,由澤 咲子,平安座 依子,斎藤 和美,辻 裕之,謝 勲東,荒瀬 康司,原 茂子,曽根 博仁
  • Organizer: 第53回日本人間ドック学会学術大会
  • Place of Presentation: 東京国際フォーラム(東京)
  • Year and Date: 2012-09-01
• [Presentation] New Risk Score for Predicting 5-year Incidence of Type 2 Diabetes in Japan: the Toranomon Hospital Health Management Center Study (2012)
  • Author(s): Heianza Y, Arase Y, Tsuji H, Yoshizawa S, Saito K, Hsieh Sd, Kodama S, Yamada N, Hara S, Sone H
  • Organizer: 72nd American Diabetes Association Scientific Sessions
  • Place of Presentation: Philadelphia, USA
  • Year and Date: 2012-06-11
• [Presentation] Quality and accuracy of Internet information concerning a healthy diet (2012)
  • Author(s): Hirasawa R, Sugawara A, SaitoK, Kodama S, Yachi Y, Yoshizawa S, Horikawa Chika, Heianza Y, Ibe Y, Sone H
  • Organizer: 72nd American Diabetes Association Scientific Sessions
  • Place of Presentation: Philadelphia, USA
  • Year and Date: 2012-06-11
• [Presentation] Low Lung Function and Risk of Type 2 Diabetes in Japanese men: the Toranomon Hospital Health Management Center Study (2012)
  • Author(s): Heianza Y, Arase Y, Tsuji H, Sugawara A, Saito K, Hsieh SD, Amakawa K, Kodama S, Yamada N, Hara S, H. Sone.
  • Organizer: 72nd American Diabetes Association Scientific Sessions
  • Place of Presentation: Philadelphia, USA
  • Year and Date: 2012-06-10
• [Presentation] Determining Optimal Combined Thresholds of HbAlc and Fasting Plasma Glucose as Predictors of Type 2 Diabetes: the Toranomon Hospital Health Management Center Study (2012)
  • Author(s): Sugawara A, Heianza Y, AraseY, Fujihara K, Tsuji H, Saito K, Hsieh SD, Kodama S, Yamada N, Hara S, Sone H
  • Organizer: 72nd American Diabetes Association Scientific Sessions
  • Place of Presentation: Philadelphia.USA
  • Year and Date: 2012-06-10
• [Presentation] Both lifetime maximum BMI and BMI change since age 20 years to maximum were strongly associated with having undiagnosed diabetes in Japanese women: Toranomon Hospital Health Management Center Study (2012)
  • Author(s): Yoshizawa S, Heianza Y, Arase Y, Tsuji H, Saito K, Hsieh SD, Kodama S, Yamada N, Hara S, Sone H
  • Organizer: 72nd American Diabetes Association Scientific Sessions
  • Place of Presentation: Philadelphia, USA
  • Year and Date: 2012-06-10
• [Presentation] Relationship between dairy intake and risk of metabolic syndrome: A-meta-analysis (2012)
  • Author(s): Horikawa C, Kodama S, Heianza Y, Hirasawa R, Sugawara A, Maki M, Yoshizawa S, Yachi Y, Saito K, Sone H
  • Organizer: 72nd American Diabetes Association Scientific Sessions
  • Place of Presentation: Philadelphia, USA
  • Year and Date: 2012-06-10
• [Presentation] Physical activity and lower risk of all-cause death and cardiovascular disease in diabetes : a meta-analysis (2012)
  • Author(s): Kodama S, Horikawa C, Tajima R, Heianza Y, Sugawara A, Maki M, Yachi Y, Iida TK, Saito K, Sone H
  • Organizer: 72nd American Diabetes Association Scientific Sessions
  • Place of Presentation: Philadelphia USA
  • Year and Date: 2012-06-08
• [Presentation] 糖尿病と難聴の関連性についてのメタ解析 (2012)
  • Author(s): 堀川 千嘉, 児玉 暁, 藤原 和哉, 平安座 依子, 菅原 歩美, 平澤 玲子, 谷内 洋子, 斎藤 和美, 曽根 博仁
  • Organizer: 第55回日本糖尿病学会年次学術集会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2012-05-19
• [Presentation] 生涯最大BMIならびに20歳から生涯最大までのBMI変化はいずれも2型糖尿病と強く関連する (2012)
  • Author(s): 由澤 咲子,平安座 依子,荒瀬 康司,斎藤 和美,辻 裕之,児玉 暁,謝 勲東,島野 仁,山田 信博,原 茂子,曽根 博仁
  • Organizer: 第55回日本糖尿病学会年次学術集会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2012-05-19
• [Presentation] HbAlcを導入した新しい2型糖尿病リスクスコアの開発 The Toranomon Hospital Health Management Center Study(TOPICS) (2012)
  • Author(s): 平安座 依子,原 茂子,斎藤 和美,藤原 和哉,辻 裕之,児玉 暁,謝 勲東,島野 仁,荒瀬 康司,山田 信博,曽根 博仁
  • Organizer: 第55回日本糖尿病学会年次学術集会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2012-05-18
• [Presentation] 2型糖尿病発症に至るまでのHbAlc値と空腹時血糖値の長期変化に関する検討TOPICS (2012)
  • Author(s): 原 茂子,平安座 依子,斎藤 和美,藤原 和哉,辻 裕之,児玉 暁,謝 勲東,島野 仁,荒瀬 康司,山田 信博,曽根 博仁
  • Organizer: 第55回日本糖尿病学会年次学術集会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2012-05-18
• [Presentation] 高脂肪食と糖尿病発症リスクの関連性についてのメタ解析 (2012)
  • Author(s): 田島 諒子,児玉 暁,藤原 和哉,平安座 依子,菅原 歩美,平澤 玲子,谷内 洋子,斎藤 和美,飯田 薫子,曽根 博仁
  • Organizer: 第55回日本糖尿病学会年次学術集会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2012-05-18
• [Presentation] フラミンガムリスクスコア、UKPDSリスクエンジン、max-IMT、LDL/HDL比による冠動脈病変予測能に関する検討 (2012)
  • Author(s): 藤原 和哉,鈴木 浩明,佐藤 明,大崎 芳典,尾本 美代子,豊島 晶子,平安座 依子,児玉 暁,斎藤 和美,小林 和人,矢藤 繁,高橋 昭光,山田 信博,曽根 博仁,島野 仁
  • Organizer: 第55回日本糖尿病学会年次学術集会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2012-05-18
• [Presentation] Relationship between obstructive sleep apnea and diabetes risk-A metaanalysis- (2012)
  • Author(s): Fujihara K, Kodama S, Horikawa C, Heianza Y, Sugawara A, Maki M, Yachi Y, Shimano H, Saito K, Sone H
  • Organizer: 72nd American Diabetes Association Scientific Sessions
  • Place of Presentation: Philadelphia, USA