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Study of preventive and early treatment for periodontitis and pulaiti s on person of advanced years

Research Project

Project/Area Number 13307055
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Conservative dentistry
Research InstitutionAsahi University

Principal Investigator

YAMAMOTO Koji  Asahi UNV., school of dentistry, Professer, 歯学部, 教授 (60182622)

Co-Investigator(Kenkyū-buntansha) TURUMATI Tamotu  Nihon UNV., School of Dentistry, Assistant Professer, 歯学部, 講師 (60139201)
SHOUJI Sigeru  Tohoku UNV., Graduate School of Dentistry, Assistant Professer, 歯学部付属病院, 講師 (10142986)
KATO Yosiro  The Nippon Dental UNV., School of Dentistry Niigata, professer, 新潟歯学部, 教授 (20060452)
NISIMURA Hideki  Okayama UNV., Graduate School Medicine and Dentistry, Assistant Professer, 歯学部付属病院, 講師 (80208222)
KITAMURA Masahiro  Osaka UNV., Graduate School of Dentistry, Asslstant Professer, 歯学部付属病院, 講師 (10243247)
Project Period (FY) 2001 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥33,150,000 (Direct Cost: ¥25,500,000、Indirect Cost: ¥7,650,000)
Fiscal Year 2003: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2002: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2001: ¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Keywordselder / ealy dental treatment / canes / periodontal / pulp capping / Er : YAGlaser / auti-plaque / root caries
Research Abstract

Study of preventive and early treatment for periodontitis and pulaitis on person of advanced years weve exaimed and the results weve as follows :
1.Auti-microbial periodontal treatwent decrease c-reactive protein level in patieuts who aer at high risk for coronany huart disese.
2.The usefulness of supportive periodoutal therapy (SPT) weve evaluated on maitenance of peridontal patieuts.SPT on maintenance of preiodontal patients was useful for the conservation of residual teeth.
3.There is a relationship between of the tubules at specifie areas of tooth and age grope, but the correlation was not precise.
4.Histopathological study on the periapical tissue reaction of tooth canal enlarged using Er : YAGleaser ware examined tested tips could abrade and vaporize pulp tissue, predentin and dentin.
5.Microscopie observation of dentiu-pulp complex weve examined in elderiy.The change of Dentin-pulp complex was depended on age.
6.A fluoride-releasing composite reins and bonding agents atowed a high calcification to dentin.
7.Composite resin including autiacterial zeolite showed no cytotoxicity.
8.Plaque accumulation on S-PRG (surface reaction type Pre-Reactecl Glass lonomer)resin was significautly inhibited and thin layer-like interfacs substance observed on these surface.
These results plays an important role in dental treateut for a person of advanced years.

Report

(4 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • Research Products

    (35 results)

All Other

All Publications (35 results)

  • [Publications] Nishimura F: "Porphyromonas gingivalis infection is associated with elevated C-reactive protein in nonobese Japanese type 2 diabetic subjects."Diabetes Care. 25. 1888 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Nishimura F: "Periodontal disease and diabetes mellitus : the role of tumor necrosis factor-alpha in a 2-way relationship"J Periodontol. 74. 97-102 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Iwamoto Y: "Anti-microbial periodontal treatment decreases serum c-reactive protein, tumor necrosis factor-alpha, but not adiponectin levels in patients with chronic adult periodontitis."J Periodontol. 74. 1231-1236 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Soga Y: "Tumor necrosis factor-alpha gene (TNF-a)-1031/863, -857 single nucleotide polymorphisms (SNPs) are associated with severe adult periodontitis in Japanese."J Clin Periodontol. 30. 524-531 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Naruishi K: "C-jun N-terminal kinase(JNK)inhibitor, SP600125, blocks interleukin (IL)-6-induced vascular endothelial growth factor(VEGF) production."Transplantation. 76. 1380-1382 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 北村正博: "歯周炎患者のメインテナンスにおけるSupportive periodontal therapyの効果"日本歯科保存学雑誌. 46. 613-618 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 庄司 茂: "Er : YAGレーザを用いた抜髄後に、即時根管充填を行った歯の根尖部歯周組織反応に関する病理組織学的研究"日本歯内療法学会雑誌. 3. (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 加藤喜朗: "歯髄保護と接着-レーザーと新規接着性レジンによる象牙質・歯髄複合体の保護ならびに接着修復の要点"接着歯学. 21. 243-245 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Takahashi A: "In vivo long-term durability of the bond to dentin using two adhesive systems."Journal of Adhesive Dentistry. 4. 151-159 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 山本宏治: "S-PRGフィラー配合レジン界面に形成されるフィルム様構造物"日歯保存誌. 47. 391-402 (2004)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Nishimura P, Taniguchi A, Iwamoto Y, Soga Y, Fukushima M, Nagasaka S, Nakai Y, Murayama Y.: "Porphyromonas gingivalis infection is associated with elevated C-reactive. protein in nonobase Japanese type 2 diabetic subjects."Diabetes Care. 25. 1888 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Nishimura F, Iwamoto Y, Mineshiba J, Shimizu A, Soga Y, Murayama Y.: "Periodontal disease and diabetes mellitus : the role of tumor necrosis factor-alpha in a 2-way relationshi"J Periodortol.. 74. 97-102 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Iwamoto Y, Nishimura F, Soga Y, Takeuchi K, Kurihara M, Takashiba S, Murayama Y.: "Anti-microbial periodontal treatment decreases serum c-reactive protein, tumor necrosis factor-alpha, but not adiponectin level in patients with chronic adult periodontitis"J Periodontol. 74. 1231-1236 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Soga Y, Nishimura F, Ohyama H, Maeda H, Takashiba S, Murayama Y.: "Tumor necrosis factor-alpha gene (TNF-a)-1031/-863, -857 single nucleotide polymorphisms (SNPs) are associated with severe adult periodontitis in Jananese."J Clin Periodontol.. 30. 524-531 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Naruishi K, Nishimura F, Yamada-Naruishi H, Omori K, Yamaguchi M, Takashiba S.: "C-jun N-terminal kinase (JNK) inhibitor, SP600125, blocks interleukin (IL)-6-induced vascular endothelial growth factor (VEGF) production : cyclosporine A partially mimics this inhibitory effect."Transplantation. 76. 1380-1382 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kitamura M. et al.: "The Longitudinal Effects of Supportive Periodontal Therapy on Maintenance of"Periodontal Patient Japan J. Conservb. Dent.. 46(5). 613-618 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Shiji S. et al.: "Histopathological study on the periapical tissue reaction of tooth canal enlarged using Er : YAG laser and filled Immediately."JJEA. 226(2). 101-105 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Katoh Y. et al.: "Microscopic Observation of Dentin-Pulp Complex in Ederly."Adhes Dent. 21(3). 243-245 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Takahashi A., Inoue S., Kawamoto C., Ominato R., Tanaka T., Sato Y., Pereira N.R., Sano H: "In vivo long-term durability of the bond to dentin using two adhesive systems."Journal of Adhesive Dentistry. 4. 151-159 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yamamoto.K.et al.: "Study on the Film Layer Produced from S-PRG Filler"Japan J. Conserv. Dent.. 47(3). 391-402 (2004)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 山本 宏治: "高齢者根面う蝕の抗菌修復材の検討"第200回日本歯科保存学会. (発表予定).

    • Related Report
      2003 Annual Research Report
  • [Publications] 堀田 正人: "高齢者根面う蝕の抗菌修復材の検討"第200回日本歯科保存学会. (発表予定).

    • Related Report
      2003 Annual Research Report
  • [Publications] 西村 英紀: "高齢者が歯周治療にとって受ける生体応答の実体"第200回日本歯科保存学会. (発表予定).

    • Related Report
      2003 Annual Research Report
  • [Publications] 庄司 茂: "レーザー照射による歯周ポケット内細菌叢の改善"第200回日本歯科保存学会. (発表予定).

    • Related Report
      2003 Annual Research Report
  • [Publications] 加藤 喜郎: "高齢者歯髄組織像の光顕的観察"第200回日本歯科保存学会. (発表予定).

    • Related Report
      2003 Annual Research Report
  • [Publications] 鶴町 保: "加齢に伴う歯髄腔壁の微細形態学的研究"第200回日本歯科保存学会. (発表予定).

    • Related Report
      2003 Annual Research Report
  • [Publications] 北村 正博: "高齢者の歯周組織の臨床的評価と全身疾患の有無の判定"第200回日本歯科保存学会. (発表予定).

    • Related Report
      2003 Annual Research Report
  • [Publications] 山本 宏治: "高齢者根面う蝕の抗菌修復材の検討"第118回〜119回日本歯科保存学会. (発表予定).

    • Related Report
      2002 Annual Research Report
  • [Publications] 堀田 正人: "高齢者根面う蝕の抗菌修復材の検討"第118回〜119回日本歯科保存学会. (発表予定).

    • Related Report
      2002 Annual Research Report
  • [Publications] 川本 千春: "歯頚部根面う蝕の進行制御法に関する研究"第118回〜119回日本歯科保存学会. (発表予定).

    • Related Report
      2002 Annual Research Report
  • [Publications] 庄司 茂: "レーザー照射による歯周ポケット内細菌叢の改善"第118回〜119回日本歯科保存学会. (発表予定).

    • Related Report
      2002 Annual Research Report
  • [Publications] 加藤 喜郎: "高齢者歯髄組織像の光顕的観察"第118回〜119回日本歯科保存学会. (発表予定).

    • Related Report
      2002 Annual Research Report
  • [Publications] 鶴町 保: "加齢に伴う歯髄腔壁の微細形態学的研究"第118回〜119回日本歯科保存学会. (発表予定).

    • Related Report
      2002 Annual Research Report
  • [Publications] 北村 正博: "高齢者の歯周組織の臨床的評価と全身疾患の有無の判定"第118回〜119回日本歯科保存学会. (発表予定).

    • Related Report
      2002 Annual Research Report
  • [Publications] 西村 英紀: "高齢者が歯周治療にとって受ける生体応答の実体"第118回〜119回日本歯科保存学会. (発表予定).

    • Related Report
      2002 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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