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Development of implant biomaterials for human body by a new method using two excimer lasers

Research Project

Project/Area Number 13450301
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Material processing/treatments
Research InstitutionKinki University

Principal Investigator

NAKAYAMA Takeyoshi  Kinki University, Dep.of Electric and Electronic Eng., Professor, 理工学部, 教授 (60023313)

Co-Investigator(Kenkyū-buntansha) HASHISHIN Yuichi  Kinki University, Dep.of Electric and Electronic Eng., Associate Professor, 理工学部, 助教授 (90156266)
NAKATA Junichi  Kinki University, Dep.of Electric and Electronic Eng., Associate Professor, 理工学部, 助教授 (80122076)
甲藤 正人  近畿大学, 理工学部, 講師 (80268466)
Project Period (FY) 2001 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥4,800,000 (Direct Cost: ¥4,800,000)
Fiscal Year 2003: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2002: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2001: ¥1,800,000 (Direct Cost: ¥1,800,000)
KeywordsLaser ablation / LALA method / Surface modification / Biocompatible materials / Hydroxyapatite / Titanium / Ceramics / Alumina / レーザー照射
Research Abstract

The aim of this project is the development of a biocompatible material that is implanted in living human body by using excimer laser irradiation method.
The results obtained in this project are as follows ;
A.Development of biocompatible material
(1)Formation of hydroxyapatite(HAp) layer on Al_2O_3 substrate by excimer laser irradiation method was achieved.
(2)Formation of a new bone on the surface of the above-mentioned sample was observed when the sample was immersed in stimulated body fluid(SBF) for 2 weeks.
B.Effect of crystalline condition of HAp target on coating layer
Growth of HAp coating layer in SBF has been observed only when the slab crystal target was used.
C.Development of a new method for HAp coating on biocompatible materials
(1)The laser assisted-laser ablation(LALA) method was developed by using KrF and ArF excimer lasers.
(2)High quality hydroxyapatite coating was obtained by control the irradiation timing of assist laser.
These results were reported in the international conference of APLS'2000(invited), FSE2001,IMLAS'03,COLA'03 and many domestic conferences.

Report

(4 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • Research Products

    (27 results)

All Other

All Publications (27 results)

  • [Publications] T.Nakayama, T.Tanaka, Y.Tsumoto, H.Katayama, M.Kato: "High quality hydroxyapatite coating on biocompatible materials by laser-assisted laser ablation method"Applied Physics. A(in print). (2004)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Katto, M.Nakamura, T.Tanaka, T.Matsutani, M.Kuwata: "Hydroxyapatite coatings using novel pulsed laser ablation methods"Surface and Coatings Technology. 169/170. 712-715 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Katto, M.Nakamura, T.Tanaka, T.Nakayama: "Hydroxyapatite coatings deposited by laser-assisted laser ablation method"Applied Surface Science. 197/198. 768-771 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] T.Nakayama, M.Kuwata, T.Matsutani: "New hydroxyapatite coating method for biocompatible material"Chinese Journal of Lasers. B10 Suppl.. VI1-VI6 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 甲藤正人, 黒沢宏, 中山斌義, 塚本雅裕, 瀧川靖雄, 高橋健治: "パルスレーザー堆積法による機能性材料皮膜の形成-構造制御と基礎課程の解明に向けて-"レーザー学会第317回研究会報告. RTM-03-44. 37-42 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 甲藤正人, 中村昌弘, 田中俊治, 中山斌義: "レーザーアブレーション法によるHApコーティング層のターゲット材料効果"レーザー学会第289回研究会報告. RTM-01-29. 86-90 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 中山 斌義 他9名: "レーザー血行再建術(「循環器科」特別増刊号、第3章分担執筆)"科学評論社. 170(25) (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] T.Nakayama, T.Tanaka, Y.Tsumoto, H.Katayama, M.Katto: "High quality hydroxyapatite coating on biocompatible materials by laser-assisted laser ablation method"Applied Physics A. (in print). (2004)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Katto, M.Nakamura, T.Tanaka, T.Matsutani, M.Kuwata, T.Nakayama: "Hydroxyapatite coatings using novel pulsed laser ablation methods"Surface and Coatings Technology. 169/170. 712-715 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Katto, M.Nakamura, T.Tanaka, T.Nakayama: "Hydroxyapatite coatings deposited by laser-assisted laser ablation method"Applied Surface Science. 197/198. 768-771 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] T.Nakayama, M.Kuwata, T.Matsutani: "New hydroxyapatite coating method for biocompatible material"Chinese Journal of Lasers. B10 Suppl.. VI1-VI6 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Katto, H.Kurosawa, T.Nakayama, M.Tsukamoto, Y.Takikawa, K.Takahashi: "Films and coatings of functional materials made by pulsed laser deposition, towards crystalline-controlled deposition and observation of its initial state(in Japanese)"Report on the 317^<th> Topical Meeting of the Laser Society of Japan. RTM-03-44. 37-42 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Katto, H.Kurosawa, T.Nakayama, M.Tsukamoto, Y.Takikawa, K.Takahashi: "Hydroxyapatite coatings formed by pulsed laser ablation methods with target of different crystallinity(in Japanese)"Report on the 2897^<th> Topical Meeting of the Laser Society of Japan. RTM-01-29. 86-90 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] T.Nakayama, T.Tanaka, Y.Tsumoto, H.Katayama, M.Katto: "High quality hydroxyapatite coating on biocompatible materials by laser-assisted laser ablation method"Applied Physics. A(in print). (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] M Katto, M.Nakamura, T.Tanaka, T.Matsutani, M.Kuwata, T.Nakayama: "Hydroxyapatite coatings using novel pulsed laser ablation methods"Surface and Coatings Technology. 169/1970. 712-715 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Katto, M.Nakamura, T.Tanaka, T.Nakayama: "Hydroxyapatite coatings deposited by laser-assisted laser ablation method"Applied Surface Science. 197/198. 768-771 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] T.Nakayama, M.Kuwata, T.Matsutani: "New hydroxyapatite coating method for biocompatible material"Chinese Journal of Lasers. B10 Suppl.. VI1-VI6 (2001)

    • Related Report
      2003 Annual Research Report
  • [Publications] 甲藤正人, 黒沢宏, 中山斌義, 塚本雅裕, 瀧川靖雄, 高橋健治: "パルスレーザー堆積法による機能性材料皮膜の形成-構造制御と基礎課程の解明に向けて-"レーザー学会第317回研究会報告. RTM-03-44. 37-42 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 甲藤正人, 中村昌弘, 田中俊治, 中山斌義: "レーザーアブレーション法によるHApコーティング層のターゲット材料効果"レーザー学会第289回研究会報告. RTM-01-29. 86-90 (2001)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中山 斌義 他9名: "レーザー血行再建術(「循環器科」特別増刊号、第3章 分担執筆)"科学評論杜. 170(25) (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Katto, M.Nakamura, T.Tanaka, T.Nakayama: "Hydroxyapatite coatings deposited by laser-assisted laser ablation method"Applied Surface Science. 197/198. 768-771 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] T.Nakayama, M.Kuwata, T.Matsutani: "New hydroxyapatite coating method for biocompatible material"Chinese Journal of Lasers. B10 Suppl.. VI1-VI6 (2001)

    • Related Report
      2002 Annual Research Report
  • [Publications] 甲藤正人, 中村昌弘, 田中俊治, 中山斌義: "レーザーアブレーション法によるHApコーティング層のターゲット材料効果"レーザー学会第289回研究会報告. RTM-01-29. 86-90 (2001)

    • Related Report
      2002 Annual Research Report
  • [Publications] 福見俊夫(監修), 中山斌義(分担): "新編 光学材料ハンドブック (第1章5節分担執筆)"リアライズ社. 715 (2000)

    • Related Report
      2002 Annual Research Report
  • [Publications] T.Nakayama, M.Kuwata, T.Matsutani: "New hydroxyapatite coating method for biocompatible material"Chinese Journal of Lasers. B10Suppl.. VI1-VI6 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 甲藤正人, 中村昌弘, 田中俊治, 中山斌義: "レーザーアブレーション法によるHApコーティング層のターゲット材料効果"レーザー学会第289回研究会報告. RTM-01-29. 86-90 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 福見 俊夫(監修): "新編 光学材料ハンドブック(第1章5節分担執筆)"リアライズ社. 715(11) (2000)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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