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Do electromagnetic fields including cellular phone make brain tumor? -Epidemiological study-

Research Project

Project/Area Number 13470098
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionJikei University School of Medicine

Principal Investigator

SHIMIZU Hidesuke  JIKEL UNIVERSITY, School of Medicine, Professor, 医学部, 教授 (80056879)

Co-Investigator(Kenkyū-buntansha) NARUSE Shoji  Kyoto Pref University, School of Medicine, Associate Professor, 医学部, 助教授 (50106407)
AGATA Toshihiko  JIKEL UNIVERSITY, School of Medicine, Associate Professor, 医学部, 助教授 (50147576)
SUZUKI Yuji  JIKEL UNIVERSITY, School of Medicine, Associate Professor, 医学部, 助教授 (30163017)
NAKAMURA Yoshiyuki  Tokyo Inst of Technology, Chemical R Lab, Research Assistant, 資源化学研究所, 助手 (90155870)
豊島 裕子  東京慈恵会医科大学, 医学部, 助手 (70328342)
Project Period (FY) 2001 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥14,100,000 (Direct Cost: ¥14,100,000)
Fiscal Year 2003: ¥3,800,000 (Direct Cost: ¥3,800,000)
Fiscal Year 2002: ¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2001: ¥6,700,000 (Direct Cost: ¥6,700,000)
Keywordselectromagnetic fields (EMFs) / infantile leukemia / epidemioloaical study / health / Ames test / questionnaire survey / cellular phone / Magnetic Resonance in Medicine
Research Abstract

It is supported by some epiderniological studies that the incidence of infantile leukemia increased by exposure to electromagnetic fields (EMFs). We investigate whether the chromosome aberration can be induced by exposure to EMFs. New born rats and their astrocytes were exposed to 10mT (50Hz) of EMFs for 7 days. The frequency of micronuclei in newborn rats of exposure group increased significantly. But there is no difference by Ames tests.
In order to make clear the influence of the workers in EMFs we made epidemiological studies. We did questionnaire survey to the workers(members of J S of Magnetic Resonance in Medicine) and controls. Response rates of the workers and controls were 28 % (864/3076) and 14% (172/1213). For sex distributions males were 705(88%) for the workers and 100(61%) for controls. Mean age and SD of the workers were 42.0 +/-7.9 for male and 38.3 +/-8.2 for female. And those of controls were 42.5 +/-11.8, 28.4+/-5.9 as follows. We surveyed 104 medical and 128 engineering students to know influences of cellular phone. Ownership rates of that were 98% for medical and 91% for engineering students. We surveyed if effects of cellular phone to health were shoulder discomfort, nausea, headache or auditory sense.
And we surveyed components of blood and urine, time tables of daily life, monitoring of EMFs level of individuals in 5 days and EMFs level of work space of the main 8 workers. Sex of 8 workers was male only. Mean age and SD of the 8 workers were 34.8 +/-14.2. Main items of blood and urine tests were 17-KS, 17-OHCS, cortisol, melatonin, LDH, LDH-isozyme and so on.

Report

(4 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • Research Products

    (25 results)

All Other

All Publications (25 results)

  • [Publications] T Suzuki, M Kurozume, Y Nakamura, Francesco Pomati, Brett A.Neilan: "Variations in Intracellular Phosphorous and Growth of the Halotolerant Alga Dunaliella parva as Influenced by Environmental Conditions."Journal of Toyo University, Natural Science. 47. 1-16 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] T Yamamoto, Y Fujiwara, H Fukumoto, Y Nakamura, S Koshihara, Tadahiko Ishikawa: "Preparation of a new poly(p-phenylene)type polymer, poly(pyrazine-2,5-diyl),with a coplanar structure."Polymer. 44. 4487-4490 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M Fukushima, E Yasuda, Y Nakamura, Y Tanabe: "Pyrolysis Behavior of Organic-Inorganic Hybrids withSi-O-Nb/Si-O-Ta Oxygen Bridgen Heterometallic Bonds."J.Ceram.Soc.Jpn.. 111. 857-859 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 宮越雄一, 鈴木勇司, 清水英佑: "電磁場の変異原性の検討(第1報)-In vivoラット・アストロサイト染色体異常試験を用いて-"日本衛生学雑誌. 58・1. 138 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 宮越雄一, 鈴木勇司, 清水英佑: "電磁場曝露の脳腫瘍誘発生の検討(第2報In vivoラットアストロサイト小核試験を用いて-"産業衛生学雑誌 第76回日本産業衛生学会講演集(山口). 45・臨時増刊号. 532 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Suzuki Y, Ikehata M, Nakamura K, Nishioka M, AsanumaK, Koana T, Shimizu H.: "Induction of micronuclei in mice exposed to static magnetic fields."Mutagenesis. 427. 499-501 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Ikehata M, Takashima Y, Suzuki Y, Shimizu H, Miyakoshi J, Koana T.: "Exposure to a power frequency magnetic field (50 Hz, 40 mT) did not cause point mutation in bacteria"Environ Mutagen Res. 23. 215-222 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Guan-Yeow Yeap, Whui-Shan Ooi, Y Nakamura, Zhang Cheng: "Synthesis and Mesomorphic Properties of Schiff Base Esters p-n-Octa-Decanoyloxybenzyldene-p-Cyano-, p-Hydroxy-, p-Nitro-and p-Carboxyanilines"Molecular Crystals and Liquid Crystals. 382. 169-178 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Manabu Fukushima, Eiichi Yasuda, Larit M.Manocha, Satish M.Manocha, Yoshiyuki Nakamura, Takashi Akatsu, Yasuhiro Tanabe: "Synthesis via Pyrolysis and Characterization of Si-C-O Ceramics from 1,4-Butane-diol and Methyl-triethoxysilane"J.Ceram.Soc.Japan. 110,12. 1044-1047 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yoshikuni Uchida, Hideaki Baba, Yoshiyuki Nakamura, Kazunori Matsui: "Spectrscopic Characterization of Sol-gel Silica Derived from 3-Aminopropyl-Triethoxysilane"Transactions of the Materials Research Society of Japan. 27,4. 771-774 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Takahiro Suzuki, Masahiro Kurozume, Yoshiyuki Nakamura, Francesco Pomati, Brett A.Neilan: "Variations in Intracellular Phosphorous and Growth of the Halotolerant Alga Dunaliella parva as Influenced by Environmental Conditions"Journal of Toyo University, Natural Science. No47. 1-16 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Takakazu Yamamoto, Yoshiki Fujiwara, Hiroki Fukumoto, Yoshiyuki Nakamura, Shinya Koshihara, Tadahiko Ishikawa: "Preparation of a new poly(p-phenylene)type polymer, poly (pyrazine-2,5-diyl), with a coplanar structure."Polymer. 44. 4487-4490 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Manabu Fukushima, Eiichi Yasuda, Yoshiyuki Nakamura, Yasuhiro Tanabe: "Pyrolysis Behavior of Organic-Inorganic Hybrids with Si-O-Nb/Si-O-Ta Oxygen Bridgen Heterometallic Bonds."J.Ceram.Soc.Jpn.. 111,11. 857-859 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Takahiro Suzuki, Masahiro Kurozume, Yoshiyuki Nakamura, Francesco Pomati, Brett A.Neilan: "Variations in Intracellular Phosphorous and Growth of the Halotolerant Alga Dunaliella parva as Influenced by Environmental Conditions."Journal of Tokyo University, Natural Science. 47・3. 1-16 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Takakazu Yamamoto, Yoshiki Fujiwara, Hiroki Fukumoto, Yoshiyuki Nakamura, Shin-ya Koshihara, Tadahiko Ishikawa: "Preparation of a new poly(p-phenylene)type polymer, poly (pyrazine-2,5-diyl), with a coplanar structure."Polymer. 44. 4487-4490 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Manabu Fukushima, Eiichi Yasuda, Yoshiyuki Nakamura, Yasuhiro Tanabe: "Pyrolysis Behavior of Organic-Inorganic Hydrids with Si-O-Nb/Si-O-Ta Oxygen Bridgen Heterometallic Bonds."J.Ceram.Soc.Jpn.. 111・11. 857-859 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 宮越雄一, 鈴木勇司, 清水英佑: "電磁場の変異原性の検討(第1報)-In vivoラット・アストロサイト染色体異常試験を用いて-"日本衛生学雑誌. 58・1. 138 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 宮越雄一, 鈴木勇司, 清水英佑: "電磁場曝露の脳腫瘍誘発性の検討(第2報)-In vivo新生仔ラットアストロサイト小核試験を用いて-"産業衛生学雑誌 第76回日本産業衛生学会講演集(山口). 45・臨時増刊号. 532 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Yoshiyuki Nakamura: "Introduction of Various Research using NMR Technique : Contribution of NMR Technique to Various Research Works"15th National Symposium on Analytical Chemistry. 54 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Yuichi Miyakoshi, Yuji Suzuki, Hidesuke Shimizu: "Enhancement of mutagenic activity of cisplatin by co-exposure to 50 Hz electromagnetic fields"10th International Conference on the Combined Effects of Environmental Factors (ICCEF). 88 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Guan-Yeow Yeap, Whui-Shan Ooi, Yoshiyuki Nakamura, Zhang Cheng: "Synthesis and Mesomorphic Properties of Schiff Base Esters p-n-Octa-Decanoyloxybenzyldene-p-Cyano-, p-Hydroxy-, p-Nitro-and p-Carboxyanilines"Molecular Crystals and Liquid Crystals. 382. 169-178 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Manabu Fukushima, Eiichi Yasuda, Larit M.Manocha, Satishi M.Manocha, Yshiyuki Nakamura, Takashi Akatsu, Yashuhiro Tanabe: "Synthesis via Pyrolysis and Characterization of Si-C-O Ceram ics from 1, 4-Butane-diol and Methyl-triethoxysilane"J. Ceram. Soc. Japan. 110・12. 1044-1047 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Yoshikuni Uchida, Hideaki Baba, Yoshiyuki Nakamura, Kazunori Matsui: "Spectrscopic Characterization of Sol-gel Silica Derived from 3-Aminopropyl-Triethoxysilane"Transactions of the Materials Research Society of Japan. 27・4. 771-774 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Y Suzuki, H Shimizu (他5名): "Induction of micronuclei in mice by exposure to static magne tic fields"Mutagenesis. 16・6. 499-501 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] M Ikehata, Y Suzuki, H Shimizu (他3名): "Exposure to a power frequency mqgnetic field(50Hz,40mT)did not cause point mutation in bacteria"Environ.Mutagen Res.. 23. 215-22 (2001)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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